Production Method 1

90-01-7

90-02-8

Reaction Conditions

1.1 Reagents: Hydrogen peroxide Catalysts: Manganese oxide (Mn3O4) ,  Poly(vinyl alcohol) ,  4-[(9-Acridinylimino)methyl]-2-methoxyphenol (Cu complex) Solvents: Water ;  4 h, 80 °C

Reference

High catalytic performance of the first electrospun nano-biohybrid, Mn3O4/copper complex/polyvinyl alcohol, from Amaranthus spinosus plant for biomimetic oxidation reactions

Naeimi, Atena ; Ekrami-Kakhki, Mehri-Saddat, Applied Organometallic Chemistry, 2020, 34(4),

Production Method 2

90-02-8

Reaction Conditions

1.1 Reagents: Sodium dodecyl sulfate ,  Hydrogen peroxide Catalysts: Ammonium iodide Solvents: Water ;  rt; 20 min, rt
1.2 Reagents: Sodium thiosulfate Solvents: Water ;  rt

Reference

Mild, efficient, and greener dethioacetalization protocol using 30% hydrogen peroxide in catalytic combination with ammonium iodide

Ganguly, Nemai C.; Mondal, Pallab, Synthetic Communications, 2011, 41(16), 2374-2384

Production Method 3

119-36-8

90-02-8

Reaction Conditions

1.1 Reagents: Hydrogen Catalysts: Alumina ,  Manganese oxide (MnO)

Reference

Preparation of aromatic aldehydes by continuous catalytic hydrogenation of aromatic acids or aromatic esters

, China, , ,

Production Method 4

90-01-7

90-02-8

Reaction Conditions

1.1 Catalysts: Tempo ,  2286259-65-0 Solvents: Acetonitrile ;  2 h, 30 °C

Reference

Base-Free Aerobic Oxidation of Alcohols over Copper-Based Complex under Ambient Condition

Mei, Qingqing ; Liu, Huizhen; Yang, Youdi; Liu, Hangyu; Li, Shaopeng; et al, ACS Sustainable Chemistry & Engineering, 2018, 6(2), 2362-2369

Production Method 5

90-01-7

90-02-8

Reaction Conditions

1.1 Reagents: Oxygen Catalysts: Tempo ,  Palladium ,  Copper Solvents: Toluene ;  overnight, 1 atm, 110 °C

Reference

Bimetallic Cu-Pd Nanoparticles Supported on Bio-silica as an Efficient Catalyst for Selective Aerobic Oxidation of Benzylic Alcohols

Buxaderas, Eduardo; Graziano-Mayer, Marilyn; Volpe, Maria Alicia; Radivoy, Gabriel, Synthesis, 2017, 49(6), 1387-1393

Production Method 6

90-01-7

90-02-8

Reaction Conditions

1.1 Reagents: Oxygen Catalysts: Titania Solvents: (Trifluoromethyl)benzene ;  30 min, 1 atm, 303 K; 6 h, 1 atm, 303 K

Reference

Visible light induced Efficient Selective Oxidation of Non-Activated Alcohols over {001} Faceted TiO2 with Molecular Oxygen

Ghosh, Subhash Chandra; Vadakkekara, Raji; Biswas, Abulkalam; Sahoo, Tapan; Pal, Provas; et al, Chemistry - An Asian Journal, 2016, 11(21), 3084-3089

Production Method 7

90-01-7

90-02-8

Reaction Conditions

1.1 Catalysts: Tempo ,  Copper(4+), bis(acetonitrile)tetraaqua[μ-[5-phenyl-2,8-di(2-pyridinyl-κN)anthyri… Solvents: Toluene ;  12 h, 100 °C

Reference

Dicopper Complexes with Anthyridine-Based Ligands: Coordination and Catalytic Activity

Huang, Da-wei; Liu, Yi-Hung; Peng, Shie-Ming; Liu, Shiuh-Tzung, Organometallics, 2016, 35(2), 151-158

Production Method 8

9005-53-2

90-02-8

488-17-5

496-16-2

876-02-8

90-00-6

93-51-6

496-78-6

527-55-9

134-96-3

121-33-5

Reaction Conditions

1.1 Catalysts: Choline chloride ,  Imidazole ;  150 °C

Reference

Insights into alkaline choline chloride-based deep eutectic solvents pretreatment for Populus deltoides: Lignin structural features and modification mechanism

Li, Haichao; et al, International Journal of Biological Macromolecules, 2021, 193, 319-327

Production Method 9

90-02-8

611-20-1

Reaction Conditions

Reference

Reactions of 1-(2-alkoxyphenyl)alkaniminyl radicals

Leardini, Rino; McNab, Hamish; Minozzi, Matteo; Nanni, Daniele; Reed, David; et al, Journal of the Chemical Society, 2001, (20), 2704-2710

Production Method 10

90-02-8

Reaction Conditions

1.1 Reagents: tert-Butyllithium ;  5 min, -78 °C
1.2 18 h, 0 °C

Reference

Total Synthesis of Palodesangren B Trimethyl Ether and D Dimethyl Ether via a Late-Stage Formation of 2H-Pyran-2-one of the Tetrahydrobenzo[c]pyranochromenone Core

Tangdenpaisal, Kassrin; Songthammawat, Poramate; Akkarasereenon, Kornkamon; Chuayboonsong, Kanokpish; Ruchirawat, Somsak; et al, Journal of Organic Chemistry, 2019, 84(21), 13410-13429

Production Method 11

90-01-7

90-02-8

Reaction Conditions

1.1 Reagents: Hydrogen peroxide Catalysts: Molybdenum (silica-coated iron oxide/PVA supported) ;  7 h, 80 °C

Reference

First electrospun immobilized molybdenum complex on bio iron oxide nanofiber for green oxidation of alcohols

Noghi, Sedighe Abbaspour; Naeimi, Atena ; Hamidian, Hooshang, Polymer, 2018, 149, 229-237

Production Method 12

84761-77-3

90-02-8

Reaction Conditions

1.1 Reagents: Cesium carbonate Solvents: Toluene ;  15 h, 80 °C
1.2 Reagents: Ethyl acetate ,  Ammonium chloride Solvents: Water

Reference

Cesium carbonate mediated aryl triflate esters' deprotection

Green, Alice E.; Agouridas, Vangelis; Deniau, Eric, Tetrahedron Letters, 2013, 54(51), 7078-7079

Production Method 13

90-01-7

90-02-8

Reaction Conditions

1.1 Reagents: Hydrogen peroxide Catalysts: 1H-Imidazolium, 3-butyl-1-methyl-, tetracosa-μ-oxoundecaoxo[μ12-[phosphato(3-)-κ… Solvents: Acetonitrile ,  Water ;  2.5 h, reflux

Reference

Selective oxidation of alcohols to aldehydes using inorganic-organic hybrid catalyst based on zinc substituted polyoxometalate and ionic liquid

Nadealian, Zahra; Mirkhani, Valiollah; Yadollahi, Bahram; Moghadam, Majid; Tangestaninejad, Shahram; et al, Journal of Coordination Chemistry, 2012, 65(6), 1071-1081

Production Method 14

90-01-7

90-02-8

Reaction Conditions

1.1 Reagents: Hydrogen peroxide Catalysts: Iron oxide (Fe3O4) ,  Ruthenium (complex with salen-modified polymer) ,  2-Propenoic acid, 2-methyl-, methyl ester, polymer with diethenylbenzene and 2-o… (salen-modified, metal complex) Solvents: Methanol ;  60 °C; 60 °C; 2.5 h, 60 °C

Reference

Synthesis and catalytic study of magnetic separable catalyst: M(Salen)-functionalized Fe3O4 polymer composite materials (M = Ru(III), Cu(II), Fe(III))

Shen, Hao-Yu; Pan, Sheng-Dong; Fang, Fang; Shi, Jia, Advanced Materials Research (Zuerich, 2011, 197, 197-198

Production Method 15

94-67-7

90-02-8

Reaction Conditions

1.1 Reagents: Sulfuric acid ,  Thallium nitrate Solvents: Methanol ,  Water ;  > 1 min, rt

Reference

Activation of iron(III) and bismuth(III) nitrates by tungstophosphoric acid. Solvent-free oxidative deprotection of oximes to carbonyl compounds

Firouzabadi, Habib; Iranpoor, Nasser; Amani, Kamal, Synthetic Communications, 2004, 34(19), 3587-3593

Production Method 16

90-01-7

90-02-8

Reaction Conditions

1.1 Reagents: Oxygen Catalysts: Ruthenium, chloronitrosyl[[2,2′-[(1,1,2,2-tetramethyl-1,2-ethanediyl)bis[(nitril… Solvents: Ethyl acetate ;  11 h, rt

Reference

(NO)Ru(salen)-catalyzed aerobic oxidation of o-hydroxybenzyl alcohol derivatives

Tashiro, Aya; Mitsuishi, Akimasa; Irie, Ryo; Katsuki, Tsutomu, Synlett, 2003, (12), 1868-1870

Production Method 17

116585-12-7

90-02-8

Reaction Conditions

1.1 Reagents: Potassium carbonate Solvents: Ethanol ,  Water

Reference

Mild base mediated desilylation of various phenolic silyl ethers

Wilson, Noel S.; Keay, Brian A., Tetrahedron Letters, 1997, 38(2), 187-190

Production Method 18

94-67-7

90-02-8

Reaction Conditions

Reference

Bis(2,2'-bipyridyl)copper(II) permanganate (BBCP): a mild and versatile oxidant in organic synthesis

Firouzabadi, H.; Sardarian, A. R.; Naderi, M.; Vessal, B., Tetrahedron, 1984, 40(23), 5001-4

Production Method 19

6630-33-7

90-02-8

Reaction Conditions

1.1 Reagents: Diisopropylethylamine ,  Water Catalysts: Nickel sulfate (NiSO4) (reaction products with bipyridine modified PSP cysteine mutants) Solvents: Dimethylformamide ;  12 h, pH 8.8, rt

Reference

Biocatalytic Cross-Coupling of Aryl Halides with a Genetically Engineered Photosensitizer Artificial Dehalogenase

Fu, Yu; Huang, Jian; Wu, Yuzhou ; Liu, Xiaohong; Zhong, Fangrui ; et al, Journal of the American Chemical Society, 2021, 143(2), 617-622

Production Method 20

5663-67-2

90-02-8

Reaction Conditions

1.1 Catalysts: Ytterbium chloride ;  1 min, 70 °C; 1 min, 70 °C → 120 °C

Reference

A Green, Solvent-Free, Microwave-Assisted, High-Yielding YbCl3 Catalyzed Deprotection of THP/MOM/Ac/Ts Ethers of Chalcone Epoxide and 2'-Aminochalcone and Their Sequel Cyclization

Kumar, Sumit; Verma, Nishant; Parveen, Iram; Ahmed, Naseem, Journal of Heterocyclic Chemistry, 2016, 53(6), 2111-2122

Production Method 21

5533-04-0

90-02-8

Reaction Conditions

1.1 Catalysts: β-Cyclodextrin Solvents: Water ;  1 min, rt; 8 min, 60 °C

Reference

β-Cyclodextrin in water: highly facile biomimetic one pot deprotection of phenolic THP/MOM/Ac/Ts ethers and concomitant regioselective cyclization of chalcone epoxides and 2'-aminochalcones

Kumar, Sumit; Verma, Nishant; Ahmed, Naseem, RSC Advances, 2015, 5(103), 85128-85138

Production Method 22

90-01-7

90-02-8

Reaction Conditions

1.1 Reagents: Oxygen Catalysts: Alumina ,  Ruthenium hydroxide Solvents: Acetonitrile ,  Toluene ;  30 min, rt; rt → 80 °C; 1 h, 11 bar, 80 °C

Reference

Continuous Flow Aerobic Alcohol Oxidation Reactions Using a Heterogeneous Ru(OH)x/Al2O3 Catalyst

Mannel, David S.; Stahl, Shannon S.; Root, Thatcher W., Organic Process Research & Development, 2014, 18(11), 1503-1508

2-Hydroxybenzaldehyde Raw materials

• Benzaldehyde, 2-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-
• 2-(Methoxymethoxy)-benzaldehyde
• Methyl salicylate
• Salicyl alcohol
• Methanesulfonic acid, trifluoro-, 2-formylphenyl ester
• Lignin
• 2-Bromobenzaldehyde
• Salicylaldoxime
• 2-Formylphenyl Acetate

2-Hydroxybenzaldehyde Preparation Products

• 3-Methylcatechol (488-17-5)
• Coumaran (496-16-2)
• 4'-Hydroxy-3'-methylacetophenone (876-02-8)
• 2-Ethylphenol (90-00-6)
• 2-Methoxy-4-methylphenol (93-51-6)
• 2,4,5-trimethylphenol (496-78-6)
• 4,5-Dimethylbenzene-1,3-diol (527-55-9)
• Syringaldehyde (134-96-3)
• Vanillin (121-33-5)
• 2-Hydroxybenzaldehyde (90-02-8)
• 2-Hydroxybenzonitrile (611-20-1)

• 1. An integrated droplet-digital microfluidic system for on-demand droplet creation, mixing, incubation, and sorting?
  Lab Chip, 2019,19, 524-535
• 2. An investigation of the electrochemical delithiation process of carbon coated α-Fe2O3nanoparticles
  Adrian Brandt,Florian Winter,Sebastian Klamor,Frank Berkemeier,Jatinkumar Rana,Rainer P?ttgen,Andrea Balducci J. Mater. Chem. A, 2013,1, 11229-11236
• 3. An approach to 7-aza-1-phosphanorbornane complexes: strain promoted rearrangement of 1-iminylphosphirane complexes and cycloaddition with olefins?
  Yang Xu,Min Wang,Donghui Wei,Rongqiang Tian,Zheng Duan,Fran?ois Mathey Dalton Trans., 2019,48, 5523-5526
• 4. An inter-tangled network of redox-active and conducting polymers as a cathode for ultrafast rechargeable batteries
  Jieun Kim,Han-Saem Park,Tae-Hee Kim,Sung Yeol Kim,Hyun-Kon Song Phys. Chem. Chem. Phys., 2014,16, 5295-5300
• 5. An approach to C–N activation: coupling of arenesulfonyl hydrazides and arenesulfonyl chlorides with tert-amines via a metal-, oxidant- and halogen-free anodic oxidation??
  M. Sheykhan,S. Khani,S. Shaabanzadeh,M. Joafshan Green Chem., 2017,19, 5940-5948

• Solvents and Organic Chemicals Organic Compounds Organic oxygen compounds Organooxygen compounds Hydroxybenzaldehydes
• Natural Products and Extracts Plant Extracts Plant based Decalepis hamiltonii
• Pesticide Chemicals Pesticide Active Ingredients Standard Substances
• Solvents and Organic Chemicals Organic Compounds Aldehyde/Ketone

• 81502-74-1(TFP)
• 27761-48-4(Benzaldehyde,2-hydroxy-, lithium salt (1:1))
• 3328-71-0(2,4-Dihydroxyisophthalaldehyde)
• 3328-70-9(4-Hydroxyisophthalaldehyde)
• 14695-06-8(Chromium,tris(2-hydroxybenzaldehydato-O,O')- (9CI))
• 22304-67-2(4,6-Dihydroxy-5-methyl-1,3-diformyl Benzene)
• 22578-24-1(Nickel,diaquabis[2-(hydroxy-kO)benzaldehydato-kO]- (9CI))
• 613-84-3(2-Hydroxy-5-methylbenzaldehyde)
• 3328-69-6(2,6-Diformylphenol)
• 28777-87-9(Benzaldehyde, hydroxy-)