Hydroxybenzaldehydes
Hydroxybenzaldehydes, also known as hydroxybenzaldehyde or benzaldehyde derivatives with a hydroxyl group, are a class of aromatic compounds that play significant roles in various industries including pharmaceuticals, food additives, and fragrances. These compounds feature a benzene ring bonded to an aldehyde group (-CHO) at the para position, often accompanied by a hydroxyl group (-OH). The presence of these functional groups endows them with unique chemical properties such as reduced toxicity compared to their aldehyde counterparts due to the formation of less reactive complexes.
In pharmaceutical applications, hydroxybenzaldehydes can act as precursors for drug synthesis or serve as intermediates in the development of new medications. Their ability to interact with biological targets makes them valuable tools in medicinal chemistry. In the food and beverage industry, these compounds are utilized as flavoring agents due to their characteristic almond-like aroma, which is reminiscent of benzaldehyde but modified by the hydroxyl group.
Moreover, they find use in the fragrance sector where their aromatic qualities contribute to creating complex and appealing scent profiles. The structural variations among different hydroxybenzaldehydes allow for a wide range of applications tailored to specific industrial needs, making them versatile components in modern chemistry.
| Structure | Chemical Name | CAS | MF |
|---|---|---|---|
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Benzaldehyde, 2,4-dihydroxy-6-(1E,3E)-1,3-pentadien-1-yl- | 918639-45-9 | C12H12O3 |
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3,5-Dibromo-4-hydroxybenzaldehyde | 2973-77-5 | C7H4Br2O2 |
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3-Bromo-4-hydroxybenzaldehyde | 2973-78-6 | C7H5BrO2 |
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Protocatechualdehyde | 139-85-5 | C7H6O3 |
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2,5-Dihydroxybenzaldehyde | 1194-98-5 | C7H6O3 |
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3-Chloro-2,6-dihydroxy-4-methylbenzaldehyde | 57074-21-2 | C8H7ClO3 |
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Benzaldehyde,3-[(2E,4E)-5-[(1S,2S,3S,6R)-3-(acetyloxy)-1,2,6-trimethyl-5-oxocyclohexyl]-3-methyl-2,4-pentadien-1-yl]-2,4-dihydroxy-6-methyl- | 165187-15-5 | C25H32O6 |
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Penicipyran E | 2231279-98-2 | C15H16O4 |
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Lycifuranone B | 868165-94-0 | C15H18O5 |
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2-Brom-4,5-dihydroxy-benzaldehyd | 4815-99-0 | C7H5BrO3 |
Related Literature
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Yi Cao,Yujiao Xiahou,Lixiang Xing,Xiang Zhang,Hong Li,ChenShou Wu,Haibing Xia Nanoscale, 2020,12, 20456-20466
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Ji-Ping Wei Nanoscale, 2015,7, 11815-11832
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A. B. F. da Silva,K. Capelle Phys. Chem. Chem. Phys., 2009,11, 4564-4569
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Maomao Hou,Fenglin Zhong,Qiu Jin,Enjiang Liu,Jie Feng,Tengyun Wang,Yue Gao RSC Adv., 2017,7, 34392-34400
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Abdelaziz Houmam,Emad M. Hamed Chem. Commun., 2012,48, 11328-11330
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