Production Method 1

6120-95-2

87328-17-4

Reaction Conditions

Reference

Lactonization of phenylcyclopropanecarboxylic acids

Sychkova, L. D.; et al, Zhurnal Organicheskoi Khimii, 1983, 19(7), 1445-8

Production Method 2

22286-82-4

31270-13-0

87328-17-4

Reaction Conditions

1.1 Catalysts: Iridium(1+), [4,4′-bis(1,1-dimethylethyl)-2,2′-bipyridine-κN1,κN1′]bis[3,5-diflu… Solvents: Dimethyl sulfoxide ;  12 h, rt
1.2 Reagents: Sodium carbonate Solvents: Water ;  rt
1.3 Reagents: Potassium tert-butoxide Solvents: Dimethyl sulfoxide ;  15 - 18 h, rt

Reference

Visible-Light-Promoted Redox-Neutral Cyclopropanation Reactions of α-Substituted Vinylphosphonates and Other Michael Acceptors with Chloromethyl Silicate as Methylene Transfer Reagent

Guo, Ting; et al, Advanced Synthesis & Catalysis, 2018, 360(23), 4459-4463

Production Method 3

22286-82-4

2230030-44-9

31270-13-0

87328-17-4

Reaction Conditions

1.1 Catalysts: Iridium(1+), [4,4′-bis(1,1-dimethylethyl)-2,2′-bipyridine-κN1,κN1′]bis[3,5-diflu… Solvents: Dimethyl sulfoxide ;  24 h, rt

Reference

Bromomethyl Silicate: A Robust Methylene Transfer Reagent for Radical-Polar Crossover Cyclopropanation of Alkenes

Luo, Wenping; et al, European Journal of Organic Chemistry, 2020, 2020(11), 1778-1781

Production Method 4

22286-82-4

87328-17-4

Reaction Conditions

1.1 Catalysts: 2,4,5,6-Tetra(9H-carbazol-9-yl)isophthalonitrile Solvents: Dimethyl sulfoxide ;  3 h, 35 °C

Reference

Redox-Neutral Photocatalytic Cyclopropanation via Radical/Polar Crossover

Phelan, James P.; et al, Journal of the American Chemical Society, 2018, 140(25), 8037-8047

Production Method 5

87328-17-4

Reaction Conditions

1.1 Reagents: Potassium tert-butoxide Solvents: Dimethyl sulfoxide ;  15 - 18 h, rt

Reference

Visible-Light-Promoted Redox-Neutral Cyclopropanation Reactions of α-Substituted Vinylphosphonates and Other Michael Acceptors with Chloromethyl Silicate as Methylene Transfer Reagent

Guo, Ting; et al, Advanced Synthesis & Catalysis, 2018, 360(23), 4459-4463

Production Method 6

65655-78-9

87328-17-4

Reaction Conditions

1.1 Reagents: Tributylstannane Solvents: Diethyl ether

Reference

Deamination reactions. 45. Decomposition of 1-arylcyclopropanediazonium ions

Kirmse, Wolfgang; et al, Chemische Berichte, 1986, 119(12), 3694-703

Production Method 7

6120-95-2

87328-17-4

Reaction Conditions

Reference

Polybromoaromatic compounds. II. Reactions of pentabromochlorobenzene with sodium alcoholates in pyridine

Shishkin, V. N.; et al, Zhurnal Organicheskoi Khimii, 1983, 19(7), 1449-56

Production Method 8

53696-78-9

87328-17-4

Reaction Conditions

1.1 40 °C; 30 min, 40 °C
2.1 Catalysts: 2,4,5,6-Tetra(9H-carbazol-9-yl)isophthalonitrile Solvents: Dimethyl sulfoxide ;  3 h, 35 °C

Reference

Redox-Neutral Photocatalytic Cyclopropanation via Radical/Polar Crossover

Phelan, James P.; et al, Journal of the American Chemical Society, 2018, 140(25), 8037-8047

Production Method 9

17455-13-9

52741-67-0

87328-17-4

Reaction Conditions

1.1 Reagents: Potassium methoxide Solvents: Methanol ;  3 h, rt
2.1 Catalysts: Iridium(1+), [4,4′-bis(1,1-dimethylethyl)-2,2′-bipyridine-κN1,κN1′]bis[3,5-diflu… Solvents: Dimethyl sulfoxide ;  24 h, rt

Reference

Bromomethyl Silicate: A Robust Methylene Transfer Reagent for Radical-Polar Crossover Cyclopropanation of Alkenes

Luo, Wenping; et al, European Journal of Organic Chemistry, 2020, 2020(11), 1778-1781

Production Method 10

22286-82-4

87328-17-4

Reaction Conditions

1.1 Reagents: Benzyltriethylammonium chloride ,  Sodium hydroxide Solvents: Dichloromethane ,  Water
2.1 Reagents: Tributylstannane Solvents: Diethyl ether

Reference

Deamination reactions. 45. Decomposition of 1-arylcyclopropanediazonium ions

Kirmse, Wolfgang; et al, Chemische Berichte, 1986, 119(12), 3694-703

Production Method 11

5926-26-1

87328-17-4

Reaction Conditions

1.1 Reagents: Sodium iodide Solvents: Acetonitrile ;  24 h, 60 °C
2.1 40 °C; 30 min, 40 °C
3.1 Catalysts: 2,4,5,6-Tetra(9H-carbazol-9-yl)isophthalonitrile Solvents: Dimethyl sulfoxide ;  3 h, 35 °C

Reference

Redox-Neutral Photocatalytic Cyclopropanation via Radical/Polar Crossover

Phelan, James P.; et al, Journal of the American Chemical Society, 2018, 140(25), 8037-8047

Production Method 12

22286-82-4

31270-13-0

87328-17-4

Reaction Conditions

1.1 Catalysts: Iridium(1+), [4,4′-bis(1,1-dimethylethyl)-2,2′-bipyridine-κN1,κN1′]bis[3,5-diflu… Solvents: Dimethyl sulfoxide ;  12 h, rt
1.2 Reagents: Sodium carbonate Solvents: Water ;  rt

Reference

Visible-Light-Promoted Redox-Neutral Cyclopropanation Reactions of α-Substituted Vinylphosphonates and Other Michael Acceptors with Chloromethyl Silicate as Methylene Transfer Reagent

Guo, Ting; et al, Advanced Synthesis & Catalysis, 2018, 360(23), 4459-4463

ethyl 1-phenylcyclopropanecarboxylate Raw materials

• (Chloromethyl)trimethoxysilane
• Ethyl Atropate
• 18-Crown-6
• INDEX NAME NOT YET ASSIGNED
• Silane, (bromomethyl)trimethoxy-
• 1-phenylcyclopropane-1-carboxylic acid
• Silane, (iodomethyl)trimethoxy-
• ethyl 2,2-dibromo-1-phenylcyclopropane-1-carboxylate
• Potassium(1+), (1,4,7,10,13,16-hexaoxacyclooctadecane-κO1,κO4,κO7,κO10,κO13,κO16)-, (OC-6-11)-

ethyl 1-phenylcyclopropanecarboxylate Preparation Products

• ethyl 1-phenylcyclopropanecarboxylate (87328-17-4)

• 1. An aquatic host–guest complex between a supramolecular G-quadruplex and the anticancer drug doxorubicin?
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• 3. Acenaphthenic hopanoids, a novel series of aromatised
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• 2901-23-7(Benzenebutanoic acid, a-butyl-a-phenyl-, ethyl ester)
• 2902-59-2(Benzenepropanoic acid, a,a-diphenyl-, ethyl ester)
• 15301-67-4(Benzeneacetic acid, a-ethyl-,2,2-bis[(1-oxo-2-phenylbutoxy)methyl]-1,3-propanediyl ester (9CI))
• 152590-27-7(Butanedioic acid,2-phenyl-, 4-butyl ester)
• 89407-94-3(Cyclopropanecarboxylic acid, 2-ethyl-1-phenyl-, ethyl ester)
• 105166-31-2(Hexanedioic acid, 2-methyl-2-phenyl-, 1-ethyl ester)
• 103384-88-9(Cyclopropaneacetic acid, 2-(ethoxycarbonyl)-2-phenyl-,3-hydroxypropyl ester, trans-)
• 34861-81-9(Butanedioic acid,2-phenyl-, 1,4-diethyl ester)
• 2901-17-9(Propionic acid,2-benzyl-2,3-diphenyl-, ethyl ester (7CI,8CI))
• 2901-15-7(Benzeneacetic acid, a,a-dibutyl-, ethyl ester)