Production Method 1

823-94-9

Reaction Conditions

1.1 Catalysts: Carbon nitride (C3N4) ;  80 h, 180 °C

Reference

Mesoporous graphitic carbon nitride as a versatile, metal-free catalyst for the cyclisation of functional nitriles and alkynes

Goettmann, Frederic; et al, New Journal of Chemistry, 2007, 31(8), 1455-1460

Production Method 2

823-94-9

Reaction Conditions

1.1 Reagents: Trifluoromethanesulfonic anhydride Solvents: Dichloromethane ;  12 h, rt
1.2 Reagents: Sodium bicarbonate Solvents: Water ;  rt

Reference

A practical and easy synthesis of 2,4,6-trisubstituted-s-triazines

Herrera, Antonio; et al, Synthesis, 2004, (4), 503-505

Production Method 3

2208-07-3

823-94-9

Reaction Conditions

1.1 Reagents: Potassium carbonate Solvents: Dichloromethane ,  Water ;  10 min, rt
1.2 Reagents: Acetic acid ;  12 h

Reference

Synthesis and characterization of novel blue light-conversion agents: 2-pentylene-4,6-bis((1-phenyl)-1, 3-butadiene)-1,3,5-s-triazine

Luo, Guilin; et al, Guizhou Shifan Daxue Xuebao, 2010, 28(3), 93-95

Production Method 4

1000-84-6

823-94-9

Reaction Conditions

1.1 Reagents: Acetic acid ;  25 - 30 °C; 24 h, 25 - 30 °C

Reference

Synthesis and characterisation of 2,6-di(2-hydroxy-styryl) 4-dimethyl-1,3,5-triazine

Zhou, Zi-yan; et al, Fenzi Kexue Xuebao, 2013, 29(3), 232-236

Production Method 5

1000-84-6

823-94-9

Reaction Conditions

Reference

Synthesis of the s-triazine system. III. Trimerization of imidates

Schaefer, Fred C.; et al, Journal of Organic Chemistry, 1961, 26, 2778-84

Production Method 6

823-94-9

Reaction Conditions

1.1 Reagents: Hydrochloric acid
1.2 Reagents: Potassium carbonate
2.1 Reagents: Acetic acid

Reference

Synthesis, characterization and properties of a new octupolar molecule

Qi, Xiaoyun; et al, Hubei Daxue Xuebao, 2012, 34(2), 176-179

Production Method 7

823-94-9

461-98-3

Reaction Conditions

1.1 Reagents: Ammonia Catalysts: Methanesulfonic acid, 1,1,1-trifluoro-, yttrium(3+) salt (3:1)

Reference

Lanthanide(III) ion-catalyzed reaction of ammonia and nitriles. Synthesis of 2,4,6-trisubstituted-s-triazines

Forsberg, John H.; et al, Journal of Heterocyclic Chemistry, 1988, 25(3), 767-70

Production Method 8

823-94-9

822-90-2

Reaction Conditions

1.1 Reagents: Sodium hydride Solvents: Tetrahydrofuran

Reference

Cyclotrimerization of nitriles by the reactive alkali metal hydrides

Zhang, Wen Ming; et al, Chinese Chemical Letters, 1995, 6(10), 839-42

Production Method 9

823-94-9

109-78-4

Reaction Conditions

1.1 Reagents: Naphthalene, radical ion(1-), sodium (1:1) Solvents: Tetrahydrofuran

Reference

Addition and substitution reactions of nitrile-stabilized carbanions

Arseniyadis, Simeon; et al, Organic Reactions (Hoboken, 1984, 31,

Production Method 10

613-92-3

823-94-9

1198-98-7

888-71-1

Reaction Conditions

1.1 Solvents: Acetonitrile ;  6 h, 10 kbar, 100 °C

Reference

Reaction of amidoximes with acetonitrile at high pressure

Baykov, Sergey V.; et al, Mendeleev Communications, 2016, 26(3), 264-265

Production Method 11

823-94-9

Reaction Conditions

1.1 Reagents: Hydrochloric acid Solvents: Ethanol ;  24 h, 25 °C
1.2 Reagents: Acetic acid ;  rt; 18 h, 30 °C

Reference

Synthesis of octupolar molecule 2,4,6-tris[4-[4-[N-ethyl-N-(2-hydroxyethyl)] amino-phenylazo]styryl]-s-triazine

Yang, Fei; et al, Hecheng Huaxue, 2011, 19(2), 222-224

Production Method 12

2208-07-3

823-94-9

Reaction Conditions

1.1 Reagents: Potassium carbonate Solvents: Dichloromethane ,  Water ;  7 - 10 min, 20 - 25 °C
1.2 Reagents: Acetic acid ;  30 min, 25 - 30 °C; 17 h, rt

Reference

A triazine-based multi-branched platinum acetylide complex: synthesis and photophysical properties

Guo, Jin; et al, Letters in Organic Chemistry, 2013, 10(1), 22-26

Production Method 13

2208-07-3

823-94-9

Reaction Conditions

1.1 Reagents: Potassium carbonate Solvents: Dichloromethane ,  Water ;  10 min, rt
1.2 Reagents: Acetic acid ;  12 h

Reference

Synthesis and characterization of novel blue light-conversion agent of triazine series in agricultural film

Luo, Gui-lin, Anhui Nongye Kexue, 2010, 38(29), 16090-16091

Production Method 14

1000-84-6

823-94-9

Reaction Conditions

1.1 Solvents: Acetic acid ;  24 h, 25 - 30 °C

Reference

Study on synthesis of s-triazine derivatives and their luminescence properties

Wang, Guang-rong, Huaxue Yanjiu Yu Yingyong, 2015, 27(7), 951-956

Production Method 15

1000-84-6

823-94-9

Reaction Conditions

1.1 Reagents: Acetic acid ;  rt; 1 h, rt; 26 h, rt

Reference

Novel synthesis of olefin-linked covalent organic frameworks via aldol condensation

Chen, Jiansong; et al, Huagong Jinzhan, 2021, 40(12), 6765-6776

Production Method 16

949-42-8

823-94-9

Reaction Conditions

1.1 Reagents: Cupric acetate ,  Zinc Solvents: Methanol ,  Formamide

Reference

Triazines. II. Trimethyltriazine

Grundmann, Christoph; et al, Chemische Berichte, 1951, 84, 684-8

Production Method 17

823-94-9

Reaction Conditions

1.1 Reagents: Hydrochloric acid Solvents: Benzene ;  2 h, 20 - 25 °C; 16 - 20 h, < 40 °C
2.1 Reagents: Potassium carbonate Solvents: Dichloromethane ,  Water ;  7 - 10 min, 20 - 25 °C
2.2 Reagents: Acetic acid ;  30 min, 25 - 30 °C; 17 h, rt

Reference

A triazine-based multi-branched platinum acetylide complex: synthesis and photophysical properties

Guo, Jin; et al, Letters in Organic Chemistry, 2013, 10(1), 22-26

Production Method 18

588-64-7

823-94-9

Reaction Conditions

1.1 Reagents: Trifluoromethanesulfonic acid Solvents: Acetonitrile

Reference

Formation of 1,2,4-triazoles by cation radical-induced oxidative addition of arylhydrazones of benzaldehyde and butyraldehyde to nitriles

Shine, Henry J.; et al, Journal of Organic Chemistry, 1988, 53(18), 4349-53

Production Method 19

1613-86-1

823-94-9

25283-96-9

54608-83-2

Reaction Conditions

1.1 Solvents: Acetonitrile ;  6 h, 10 kbar, 100 °C

Reference

Reaction of amidoximes with acetonitrile at high pressure

Baykov, Sergey V.; et al, Mendeleev Communications, 2016, 26(3), 264-265

Production Method 20

5373-87-5

823-94-9

5311-71-7

Reaction Conditions

1.1 Solvents: Acetonitrile ;  6 h, 10 kbar, 100 °C

Reference

Reaction of amidoximes with acetonitrile at high pressure

Baykov, Sergey V.; et al, Mendeleev Communications, 2016, 26(3), 264-265

Production Method 21

5329-33-9

1000-84-6

823-94-9

3599-66-4

Reaction Conditions

Reference

Product subclass 3: 1,3,5-triazines and phosphorus analogues

von Angerer, S., Science of Synthesis, 2004, 17, 449-583

Production Method 22

616-05-7

823-94-9

625-77-4

Reaction Conditions

Reference

High-temperature transnitrilation of 2-bromocaproic acid

Polivin, Yu. N.; et al, Izvestiya Akademii Nauk SSSR, 1990, (7), 1682-4

2,4,6-trimethyl-1,3,5-triazine Raw materials

• Ethyl Acetimidate Hydrochloride (>90%)
• Benzamide Oxime
• N-Hydroxy-4-nitrobenzimidamide
• O-Methylisourea Hydrochloride
• Ethanimidic acid, ethylester
• N'-Hydroxy-4-methoxybenzenecarboximidamide
• Benzaldehyde, phenylhydrazone
• 2-Bromohexanoic acid
• 2-Methyl-4,6-bis(trichloromethyl)-1,3,5-triazine

2,4,6-trimethyl-1,3,5-triazine Preparation Products

• 2,6-Dimethylpyrimidin-4-amine (461-98-3)
• 3-hydroxypropanenitrile (109-78-4)
• 5-Methyl-3-phenyl-1,2,4-oxadiazole (1198-98-7)
• 1,2,4-Oxadiazole, 3-(4-methoxyphenyl)-5-methyl- (5311-71-7)
• 2-methoxy-4,6-dimethyl-1,3,5-triazine (3599-66-4)
• 2,4,6-trimethyl-1,3,5-triazine (823-94-9)
• 5-methyl-3-(4-nitrophenyl)-1,2,4-oxadiazole (25283-96-9)
• N-Acetyl Acetamide (625-77-4)
• 1,2,4-Oxadiazole, 3,5-bis(4-nitrophenyl)- (54608-83-2)
• 1,2,4-Oxadiazole,3,5-diphenyl- (888-71-1)
• 2,4,5-trimethyl-1H-imidazole (822-90-2)

• 1. An approach to C–N activation: coupling of arenesulfonyl hydrazides and arenesulfonyl chlorides with tert-amines via a metal-, oxidant- and halogen-free anodic oxidation??
  M. Sheykhan,S. Khani,S. Shaabanzadeh,M. Joafshan Green Chem., 2017,19, 5940-5948
• 2. An alkynylboronatecycloaddition strategy to functionalised benzyne derivatives?
  James D. Kirkham,Patrick M. Delaney,George J. Ellames,Eleanor C. Row,Joseph P. A. Harrity Chem. Commun., 2010,46, 5154-5156
• 3. An approach to 7-aza-1-phosphanorbornane complexes: strain promoted rearrangement of 1-iminylphosphirane complexes and cycloaddition with olefins?
  Yang Xu,Min Wang,Donghui Wei,Rongqiang Tian,Zheng Duan,Fran?ois Mathey Dalton Trans., 2019,48, 5523-5526
• 4. An amphoteric reactivity of a mixed-valent bis(μ-oxo)dimanganese(iii,iv) complex acting as an electrophile and a nucleophile?
  Muniyandi Sankaralingam,So Hyun Jeon,Yong-Min Lee,Mi Sook Seo,Wonwoo Nam Dalton Trans., 2016,45, 376-383
• 5. An aquatic host–guest complex between a supramolecular G-quadruplex and the anticancer drug doxorubicin?
  José M. Rivera,Mariana Martín-Hidalgo,Jean C. Rivera-Ríos Org. Biomol. Chem., 2012,10, 7562-7565

• 188185-54-8(Methyl, 1,3,5-triazine-2,4,6-triyltris-)
• 3599-87-9(1,3,5-Triazine,2-methyl-)
• 1722-15-2(1,3,5-Triazine,2,4-dimethyl-)
• 188185-47-9(Methyl, 1,3,5-triazine-2,4-diylbis-)
• 188185-49-1(Methylene, 1,3,5-triazine-2,4-diylbis-)
• 332062-08-5(Fmoc-S-3-amino-4,4-diphenyl-butyric acid)
• 1270529-38-8(1,2,3,4,5,6-Hexahydro-[2,3]bipyridinyl-6-ol)
• 2680771-01-9(4-cyclopentyl-3-{(prop-2-en-1-yloxy)carbonylamino}butanoic acid)
• 2098070-20-1(2-(3-(Pyridin-3-yl)-1H-pyrazol-1-yl)acetimidamide)
• 1444113-98-7(N-(3-cyanothiolan-3-yl)-2-[(2,2,2-trifluoroethyl)sulfanyl]pyridine-4-carboxamide)