Production Method 1

703-67-3

804498-72-4

Reaction Conditions

1.1 Catalysts: Boron trifluoride etherate ,  Quinolinium, 3-cyano-1-methyl-, perchlorate (1:1) ,  (OC-6-11)-Bis(acetonitrile)[bis[μ-[[2,3-butanedione 2,3-di(oximato-κO)](2-)]]tet… Solvents: Acetonitrile ;  30 min, rt

Reference

Photocatalytic hydrogen evolution of 1-tetralones to α-naphthols by continuous-flow technology

He, Xu; et al, Catalysis Science & Technology, 2019, 9(13), 3337-3341

Production Method 2

804498-71-3

804498-72-4

Reaction Conditions

1.1 Reagents: p-Toluenesulfonic acid Solvents: Toluene ;  3 h, reflux; reflux → rt
1.2 Reagents: Sodium carbonate Solvents: Water ;  neutralized, rt

Reference

Synthesis of substituted naphthalenes from α-tetralones generated by a xanthate radical addition-cyclisation sequence

Cordero-Vargas, Alejandro; et al, Organic & Biomolecular Chemistry, 2004, 2(20), 3018-3025

Production Method 3

173276-82-9

804498-72-4

3132-92-1

Reaction Conditions

1.1 Reagents: Boron trifluoride etherate Solvents: Dichloromethane ;  1.5 h, 0 °C → rt

Reference

Synthesis of monofluorinated 1-(naphthalen-1-yl)piperazines

Repine, Joseph T.; et al, Tetrahedron Letters, 2007, 48(31), 5539-5541

Production Method 4

1123760-78-0

804498-72-4

Reaction Conditions

1.1 Reagents: Perchloric acid Solvents: Acetonitrile ;  rt

Reference

Acid-Catalyzed Dehydration of Naphthalene-cis-1,2-dihydrodiols: Origin of Impaired Resonance Effect of 3-Substituents

Kudavalli, Jaya Satyanarayana; et al, Journal of Organic Chemistry, 2011, 76(22), 9338-9343

Production Method 5

128400-42-0

3377-92-2

804498-72-4

Reaction Conditions

1.1 Solvents: 1,2-Dichloroethane ;  15 min, reflux
1.2 Reagents: Lauroyl peroxide ;  reflux; reflux → rt
1.3 Reagents: Lauroyl peroxide ,  Camphorsulfonic acid Solvents: 1,2-Dichloroethane ;  reflux; reflux → rt
2.1 Reagents: p-Toluenesulfonic acid Solvents: Toluene ;  3 h, reflux; reflux → rt
2.2 Reagents: Sodium carbonate Solvents: Water ;  neutralized, rt

Reference

Synthesis of substituted naphthalenes from α-tetralones generated by a xanthate radical addition-cyclisation sequence

Cordero-Vargas, Alejandro; et al, Organic & Biomolecular Chemistry, 2004, 2(20), 3018-3025

Production Method 6

173276-82-9

804498-72-4

3132-92-1

Reaction Conditions

1.1 Reagents: Boron trifluoride etherate Solvents: Dichloromethane ;  0 °C; 30 min, 0 °C; 0 °C → rt; 2 h, rt

Reference

Structural Modifications of Nile Red Carbon Monoxide Fluorescent Probe: Sensing Mechanism and Applications

Madea, Dominik; et al, Journal of Organic Chemistry, 2020, 85(5), 3473-3489

Production Method 7

348-57-2

804498-72-4

3132-92-1

Reaction Conditions

1.1 Reagents: Magnesium Solvents: Tetrahydrofuran ;  rt → 60 °C
1.2 Catalysts: Iodine Solvents: Tetrahydrofuran ;  30 min, reflux; 15 h, 65 °C; 65 °C → rt
1.3 Reagents: Water ;  rt
2.1 Reagents: Boron trifluoride etherate Solvents: Dichloromethane ;  0 °C; 30 min, 0 °C; 0 °C → rt; 2 h, rt

Reference

Structural Modifications of Nile Red Carbon Monoxide Fluorescent Probe: Sensing Mechanism and Applications

Madea, Dominik; et al, Journal of Organic Chemistry, 2020, 85(5), 3473-3489

Production Method 8

348-57-2

804498-72-4

3132-92-1

Reaction Conditions

1.1 Reagents: Magnesium Solvents: Tetrahydrofuran ;  2 h, 65 °C; 15 h, 65 °C
2.1 Reagents: Hydrochloric acid Solvents: Ethanol ;  2 h, reflux

Reference

Synthesis of monofluorinated 1-(naphthalen-1-yl)piperazines

Repine, Joseph T.; et al, Tetrahedron Letters, 2007, 48(31), 5539-5541

6-Fluoronaphthalen-1-ol Raw materials

• Propanoic acid, 2,2-dimethyl-, 7-fluoro-1,2,3,4-tetrahydro-4-oxo-1-naphthalenyl ester
• Carbonodithioic acid, O-ethyl S-[2-(4-fluorophenyl)-2-oxoethyl] ester
• 1-Bromo-2,4-difluorobenzene
• 6-fluoro-1,2,3,4-tetrahydronaphthalen-1-one
• Vinyl Pivalate
• 1,4-Epoxynaphthalene,6-fluoro-1,4-dihydro-
• 1,2-Naphthalenediol, 6-fluoro-1,2-dihydro-, (1R,2S)-

6-Fluoronaphthalen-1-ol Preparation Products

• 6-Fluoronaphthalen-1-ol (804498-72-4)
• 7-Fluoronaphthalen-1-ol (3132-92-1)

• 1. Fast synthesis of copper nanoclusters through the use of hydrogen peroxide additive and their application for the fluorescence detection of Hg2+ in water samples?
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• Solvents and Organic Chemicals Organic Compounds Benzenoids Naphthalenes Naphthols and derivatives

• 13916-98-8(8-Fluoronaphthalen-2-OL)
• 13101-83-2(2-Naphthalenol,6-fluoro-)
• 56874-95-4(2-FLUORO-1-NAPHTHOL)
• 383155-01-9(1-Naphthalenol,8-fluoro-(9CI))
• 61761-32-8(5-Fluoronaphthalen-1-ol)
• 371-41-5(4-Fluorophenol)
• 62576-77-6(Phenol, 4-fluoro-, compd. with benzene (1:1))
• 8068-44-8(6-Fluoronaphthalen-1-ol)
• 741693-88-9(5-Fluoro-2-naphthalenol)
• 315-53-7(4-Fluoro-1-naphthalenol)