Cas no 61761-32-8 (5-Fluoronaphthalen-1-ol)

5-Fluoronaphthalen-1-ol is a fluorinated naphthol derivative characterized by the presence of a hydroxyl group at the 1-position and a fluorine substituent at the 5-position of the naphthalene ring. This compound is of interest in synthetic organic chemistry due to its utility as a building block for pharmaceuticals, agrochemicals, and advanced materials. The electron-withdrawing fluorine atom enhances reactivity in electrophilic substitution reactions, while the hydroxyl group allows for further functionalization. Its structural features make it valuable for designing bioactive molecules or as a precursor in cross-coupling reactions. High purity grades are available to ensure reproducibility in research and industrial applications.
5-Fluoronaphthalen-1-ol structure
5-Fluoronaphthalen-1-ol structure
Product Name:5-Fluoronaphthalen-1-ol
CAS No:61761-32-8
MF:C10H7FO
MW:162.160386323929
MDL:MFCD12401609
CID:467153
PubChem ID:12336391
Update Time:2025-05-28

5-Fluoronaphthalen-1-ol Chemical and Physical Properties

Names and Identifiers

    • 1-Naphthalenol, 5-fluoro-
    • 5-Fluoronaphthalen-1-ol
    • 1-Fluoro-5-hydroxynaphthalin
    • 1-fluoronaphth-5-ol
    • 5-fluoro-1-naphthol
    • 5-fluoronaphthol
    • Ambpe2021296
    • CTK2D2893
    • SBB087595
    • SureCN485322
    • 61761-32-8
    • MFCD12401609
    • AKOS006345580
    • EN300-1143463
    • AS-58009
    • 5-fluoro-1-hydroxynaphthalene
    • SCHEMBL485322
    • W16628
    • DTXSID90491403
    • 1-Fluoro-5-hydroxynaphthalene
    • CS-0454225
    • KMQITEWKYHQQHH-UHFFFAOYSA-N
    • 1-Fluoro-5-naphthol
    • SY045989
    • MDL: MFCD12401609
    • Inchi: 1S/C10H7FO/c11-9-5-1-4-8-7(9)3-2-6-10(8)12/h1-6,12H
    • InChI Key: KMQITEWKYHQQHH-UHFFFAOYSA-N
    • SMILES: FC1=CC=CC2=C(C=CC=C21)O

Computed Properties

  • Exact Mass: 162.04811
  • Monoisotopic Mass: 162.048093005g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 1
  • Hydrogen Bond Acceptor Count: 1
  • Heavy Atom Count: 12
  • Rotatable Bond Count: 0
  • Complexity: 160
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • XLogP3: 2.3
  • Topological Polar Surface Area: 20.2?2

Experimental Properties

  • PSA: 20.23

5-Fluoronaphthalen-1-ol Security Information

  • HazardClass:IRRITANT

5-Fluoronaphthalen-1-ol Pricemore >>

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abcr
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Additional information on 5-Fluoronaphthalen-1-ol

1-Naphthalenol, 5-fluoro- (CAS No: 61761-32-8)

1-Naphthalenol, 5-fluoro- is a chemical compound with the CAS registry number 61761-32-8. This compound belongs to the class of naphthols, which are derivatives of naphthalene containing a hydroxyl group (-OH). The presence of a fluorine atom at the 5-position of the naphthalene ring introduces unique electronic and structural properties, making this compound a subject of interest in various fields of chemistry and materials science.

The molecular formula of 1-Naphthalenol, 5-fluoro- is C??H?FO, and its molecular weight is approximately 164.19 g/mol. The compound is characterized by its aromatic structure, which contributes to its stability and reactivity under certain conditions. The fluorine substitution at the 5-position influences the electronic distribution within the molecule, potentially enhancing its ability to participate in various chemical reactions.

Recent studies have highlighted the potential applications of 1-Naphthalenol, 5-fluoro- in the field of materials science, particularly in the synthesis of advanced materials such as organic semiconductors and functional polymers. Researchers have explored its role as a building block for constructing π-conjugated systems, which are essential for applications in electronics and optoelectronics.

In terms of synthesis, 1-Naphthalenol, 5-fluoro- can be prepared through various routes, including nucleophilic aromatic substitution and Friedel-Crafts alkylation. These methods allow for precise control over the substitution pattern on the naphthalene ring, ensuring high purity and structural integrity of the final product.

The compound has also been studied for its potential in drug discovery. Its unique structure makes it a promising candidate for designing bioactive molecules with specific pharmacological properties. Recent research has focused on its ability to interact with biological targets such as enzymes and receptors, paving the way for its use in therapeutic applications.

From an environmental perspective, 1-Naphthalenol, 5-fluoro- has been investigated for its biodegradability and toxicity profiles. Understanding these properties is crucial for assessing its environmental impact and ensuring safe handling during industrial processes.

In conclusion, 1-Naphthalenol, 5-fluoro- (CAS No: 61761-32-8) is a versatile compound with a wide range of applications across multiple disciplines. Its unique chemical properties and structural features make it an attractive target for researchers aiming to develop innovative materials and therapies. As advancements in synthetic methods and characterization techniques continue to emerge, the potential of this compound is expected to expand further.

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