Production Method 1

74315-07-4

90561-76-5

337535-82-7

Reaction Conditions

1.1 Reagents: Sulfuric acid ,  1,3,5-Triazine-2,4,6(1H,3H,5H)-trione, 1-bromo-, sodium salt (1:1) Solvents: Water ;  2.5 h, 0 °C
1.2 Reagents: Sodium hydroxide Solvents: Water ;  basified
1.3 Reagents: Pyridine ;  2 h, rt
1.4 Reagents: Water

Reference

Chemistry of unprotected amino acids in aqueous solution: direct bromination of aromatic amino acids with bromoisocyanuric acid sodium salt under strong acidic condition

Yokoyama, Yuusaku; Yamaguchi, Tomotsugu; Sato, Masanori; Kobayashi, Eri; Murakami, Yasuoki; et al, Chemical & Pharmaceutical Bulletin, 2006, 54(12), 1715-1719

N-(2-Bromobenzyl)acetamide Preparation Products

• N-(2-Bromobenzyl)acetamide (74315-07-4)
• N-(4-Bromophenyl)methylacetamide (90561-76-5)
• N-(3-Bromobenzyl)acetamide (337535-82-7)

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N-(2-Bromobenzyl)acetamide (CAS No. 74315-07-4): A Comprehensive Guide to Its Properties and Applications

N-(2-Bromobenzyl)acetamide (CAS No. 74315-07-4) is a specialized organic compound that has garnered significant attention in pharmaceutical and chemical research. With the molecular formula C₉H₁₀BrNO, this compound is characterized by its bromobenzyl moiety and acetamide functional group, making it a versatile intermediate in synthetic chemistry. Researchers and industry professionals often search for terms like N-(2-Bromobenzyl)acetamide synthesis, CAS 74315-07-4 applications, and bromobenzyl derivatives, reflecting its relevance in modern scientific inquiries.

The compound's unique structure, featuring a 2-bromobenzyl group attached to an acetamide backbone, enables its use in various pharmaceutical intermediates and organic synthesis pathways. Recent trends in drug discovery highlight the demand for halogenated aromatic compounds, such as N-(2-Bromobenzyl)acetamide, due to their potential in designing bioactive molecules. Questions like *"What are the uses of N-(2-Bromobenzyl)acetamide in medicinal chemistry?"* or *"How to purify CAS 74315-07-4?"* are frequently encountered in academic and industrial forums.

From a technical perspective, N-(2-Bromobenzyl)acetamide exhibits notable solubility in polar organic solvents like dimethyl sulfoxide (DMSO) and ethanol, which facilitates its handling in laboratory settings. Its melting point and stability under controlled conditions make it suitable for high-yield reactions. SEO-optimized queries such as N-(2-Bromobenzyl)acetamide solubility or CAS 74315-07-4 stability often arise among chemists seeking practical data for experimental designs.

In the context of green chemistry, researchers are exploring eco-friendly synthesis routes for N-(2-Bromobenzyl)acetamide to minimize waste and energy consumption. This aligns with global initiatives toward sustainable chemical production. Discussions around catalytic methods for bromobenzyl acetamide or solvent-free synthesis of CAS 74315-07-4 are gaining traction, reflecting the compound's adaptability to innovative methodologies.

Quality control and analytical techniques, such as HPLC and NMR spectroscopy, are critical for verifying the purity of N-(2-Bromobenzyl)acetamide. Laboratories frequently search for analytical standards for CAS 74315-07-4 or spectroscopic data of bromobenzyl acetamide, underscoring the need for reliable characterization tools. The compound's spectral fingerprints (e.g., IR peaks or ¹H NMR signals) are well-documented in scientific literature, aiding in its identification.

Beyond academia, N-(2-Bromobenzyl)acetamide finds niche applications in material science, particularly in the development of functionalized polymers and ligand design. Its bromine atom offers a reactive site for further modifications, enabling the creation of tailored molecules for advanced materials. Searches like N-(2-Bromobenzyl)acetamide in polymer chemistry or CAS 74315-07-4 cross-coupling reactions illustrate its interdisciplinary utility.

In summary, N-(2-Bromobenzyl)acetamide (CAS No. 74315-07-4) is a multifaceted compound with broad applicability in research and industry. Its synthesis, properties, and applications continue to evolve, driven by advancements in organic chemistry and material science. By addressing common search queries and integrating contemporary scientific trends, this guide aims to serve as a authoritative resource for professionals navigating the complexities of this valuable chemical entity.

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• 1020252-82-7(N-Ethyl 4-bromo-3-methylbenzamide)
• 1020252-76-9(N-Benzyl 4-bromo-3-methylbenzamide)
• 8002-23-1(2-Bromo-N-ethylbenzamide)
• 90561-76-5(N-(4-Bromophenyl)methylacetamide)
• 8002-73-1(2-Bromo-N-ethylbenzamide)
• 8008-31-9(2-Bromo-N-ethylbenzamide)
• 337535-82-7(N-(3-Bromobenzyl)acetamide)