- Site-selectivity in the cyanation of 3-substituted pyridine 1-oxides with trimethylsilanecarbonitrileSakamoto, Takao; Kaneda, Sohichi; Nishimura, Sumiko; Yamanaka, Hiroshi, Chemical & Pharmaceutical Bulletin, 1985, 33(2), 565-71
Cas no 38180-46-0 (3-chloropyridine-2-carbonitrile)
38180-46-0 structure
Product Name:3-chloropyridine-2-carbonitrile
CAS No:38180-46-0
MF:C6H3ClN2
MW:138.554419755936
MDL:MFCD03788834
CID:54816
PubChem ID:818258
Update Time:2025-04-18
3-chloropyridine-2-carbonitrile Chemical and Physical Properties
Names and Identifiers
-
- 3-Chloro-2-cyanopyridine
- 2-Cyano-3-chloropyridine
- 3-Chloro-2-pyridinecarbonitrile
- 3-Chloropicolinonitrile
- 3-chloropyridine-2-carbonitrile
- MFCD03788834
- A824038
- DTXSID701347474
- C3022
- CS-W008752
- EN300-105450
- chloro-2-pyridinecarbonitrile
- YDPLFBIGFQFIDB-UHFFFAOYSA-N
- 3-Chloro-2-cyanopyridine, AldrichCPR
- 3-chloropyridine-2-carbonitrile;2-CYANO-3-CHLOROPYRIDINE
- 205751-22-0
- SCHEMBL363772
- AM20051131
- chloro-2-cyanopyridine
- FT-0648883
- PS-5789
- YDPLFBIGFQFIDB-UHFFFAOYSA-
- 3-Chloro-pyridine-2-carbonitrile
- Pyridinecarbonitrile, chloro- (9CI)
- InChI=1/C6H3ClN2/c7-5-2-1-3-9-6(5)4-8/h1-3H
- AC-4594
- CL0144
- W-202559
- 38180-46-0
- AKOS005063687
- SY004407
- PB17324
- DB-015993
- BBL100612
- STL554406
-
- MDL： MFCD03788834
- Inchi： 1S/C6H3ClN2/c7-5-2-1-3-9-6(5)4-8/h1-3H
- InChI Key： YDPLFBIGFQFIDB-UHFFFAOYSA-N
- SMILES： ClC1C(C#N)=NC=CC=1
Computed Properties
- Exact Mass: 137.99800
- Monoisotopic Mass: 137.998
- Isotope Atom Count: 0
- Hydrogen Bond Donor Count: 0
- Hydrogen Bond Acceptor Count: 2
- Heavy Atom Count: 9
- Rotatable Bond Count: 0
- Complexity: 137
- Covalently-Bonded Unit Count: 1
- Defined Atom Stereocenter Count: 0
- Undefined Atom Stereocenter Count : 0
- Defined Bond Stereocenter Count: 0
- Undefined Bond Stereocenter Count: 0
- Surface Charge: 0
- Tautomer Count: nothing
- XLogP3: 1.5
- Topological Polar Surface Area: 36.7A^2
Experimental Properties
- Color/Form: Solid
- Density: 1.33
- Melting Point: 81.0 to 85.0 deg-C
- Boiling Point: 100°C/3mmHg(lit.)
- Flash Point: 111.4℃
- Refractive Index: 1.565
- PSA: 36.68000
- LogP: 1.60668
- Solubility: Not determined
3-chloropyridine-2-carbonitrile Security Information
-
Symbol:
- Prompt：dangerous
- Signal Word：Danger
- Hazard Statement： H311,H302,H332,H315,H319,H335
-
Warning Statement：
P280H,P305
P351
P338,P309,P310 - Hazardous Material transportation number：2811
- Hazard Category Code： 25-36/37/38-20/21/22
- Safety Instruction： 45-36/37-22
-
Hazardous Material Identification：
- HazardClass：IRRITANT-HARMFUL
- PackingGroup：III
- Storage Condition：Room temperature
3-chloropyridine-2-carbonitrile Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| SHANG HAI XIAN DING Biotechnology Co., Ltd. | C3022-5g |
3-chloropyridine-2-carbonitrile |
38180-46-0 | 98.0%(GC) | 5g |
￥250.0 | 2022-05-30 | |
| SHANG HAI XIAN DING Biotechnology Co., Ltd. | C3022-1g |
3-chloropyridine-2-carbonitrile |
38180-46-0 | 98.0%(GC) | 1g |
￥80.0 | 2022-05-30 | |
| SHANG HAI XIAN DING Biotechnology Co., Ltd. | C204A-5g |
3-chloropyridine-2-carbonitrile |
38180-46-0 | 98% | 5g |
￥100.0 | 2022-05-30 | |
| SHANG HAI XIAN DING Biotechnology Co., Ltd. | C204A-25g |
3-chloropyridine-2-carbonitrile |
38180-46-0 | 98% | 25g |
￥424.0 | 2022-05-30 | |
| Fluorochem | 033256-1g |
3-Chloro-pyridine-2-carbonitrile |
38180-46-0 | 95% | 1g |
￡10.00 | 2022-03-01 | |
| Fluorochem | 033256-5g |
3-Chloro-pyridine-2-carbonitrile |
38180-46-0 | 95% | 5g |
￡21.00 | 2022-03-01 | |
| Fluorochem | 033256-10g |
3-Chloro-pyridine-2-carbonitrile |
38180-46-0 | 95% | 10g |
￡33.00 | 2022-03-01 | |
| Fluorochem | 033256-25g |
3-Chloro-pyridine-2-carbonitrile |
38180-46-0 | 95% | 25g |
￡72.00 | 2022-03-01 | |
| AstaTech | CL0144-5/G |
2-CYANO-3-CHLOROPYRIDINE |
38180-46-0 | 97% | 5g |
$25 | 2023-09-15 | |
| AstaTech | CL0144-25/G |
2-CYANO-3-CHLOROPYRIDINE |
38180-46-0 | 97% | 25g |
$102 | 2023-09-15 |
3-chloropyridine-2-carbonitrile Production Method
Production Method 1
Reaction Conditions
1.1 Reagents: Triethylamine , Trimethylsilyl cyanide Solvents: Acetonitrile
Reference
Production Method 2
Reaction Conditions
1.1 Reagents: Trifluoromethanesulfonic anhydride Solvents: Chloroform ; rt; 1 h, rt
1.2 3 h, 60 °C; < 60 °C
1.3 Reagents: 4-Methylmorpholine ; 17 h, 60 °C; 60 °C → rt
1.4 Reagents: Sodium bicarbonate Solvents: Water ; rt
1.2 3 h, 60 °C; < 60 °C
1.3 Reagents: 4-Methylmorpholine ; 17 h, 60 °C; 60 °C → rt
1.4 Reagents: Sodium bicarbonate Solvents: Water ; rt
Reference
- C-H Cyanation of 6-Ring N-Containing HeteroaromaticsElbert, Bryony L.; Farley, Alistair J. M.; Gorman, Timothy W.; Johnson, Tarn C.; Genicot, Christophe; et al, Chemistry - A European Journal, 2017, 23(59), 14733-14737
3-chloropyridine-2-carbonitrile Raw materials
3-chloropyridine-2-carbonitrile Preparation Products
3-chloropyridine-2-carbonitrile Suppliers
Tiancheng Chemical (Jiangsu) Co., Ltd
Gold Member
Audited Supplier
(CAS:38180-46-0)3-氯-2-氰基吡啶
Order Number:LE5731359
Stock Status:in Stock
Quantity:25KG,200KG,1000KG
Purity:99%
Pricing Information Last Updated:Friday, 20 June 2025 12:45
Price ($):discuss personally
Email:[email protected]
Suzhou Senfeida Chemical Co., Ltd
Gold Member
Audited Supplier
(CAS:38180-46-0)2-Cyano-3-chloropyridine
Order Number:sfd6644
Stock Status:in Stock
Quantity:200kg
Purity:99.9%
Pricing Information Last Updated:Friday, 19 July 2024 14:34
Price ($):discuss personally
Email:[email protected]
3-chloropyridine-2-carbonitrile Related Literature
-
1. Reactions of halogenomethanes in the vapour phase. Part 5. The reactions of imidazolines, anils, and 1-methylimidazole with chloroform at 550 °C, and a comparison with their liquid-phase reactions with trichloroacetate ion or hexachloroacetone and baseReginald E. Busby,Mohammad A. Khan,Mohammad R. Khan,John Parrick,C. J. Granville Shaw J. Chem. Soc. Perkin Trans. 1 1980 1431
-
Wensheng Yu,Paul G. Bulger,Kevin M. Maloney Green Chem. 2016 18 4941
38180-46-0 (3-chloropyridine-2-carbonitrile) Related Products
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- 945557-04-0(5-Bromo-3-chloropyridine-2-carbonitrile)
- 1702-18-7(3,6-dichloropyridine-2-carbonitrile)
- 72093-03-9(3-Chloro-2-methylpyridine)
- 61893-86-5(1H-Pyrrole-2-carbonitrile, 3-chloro-)
- 23994-20-9(4-Chloroisoquinoline-1-carbonitrile)
- 74960-46-6(3-Chloro-1H-indole-2-carbonitrile)
- 139485-42-0(3,4,5-Trichloropicolinonitrile)
