Cas no 1851-22-5 (3-Chloropyridine N-Oxide)

3-Chloropyridine N-Oxide is a heterocyclic compound featuring a chlorinated pyridine ring with an N-oxide functional group. This structure imparts unique reactivity, making it a valuable intermediate in organic synthesis, particularly in pharmaceutical and agrochemical applications. The N-oxide moiety enhances electrophilic substitution reactions, while the chlorine atom offers a versatile site for further functionalization. Its stability under standard conditions and compatibility with various reaction conditions make it a practical choice for constructing complex molecules. The compound is often utilized in the development of active ingredients, ligands, and catalysts, demonstrating broad utility in medicinal chemistry and material science.
3-Chloropyridine N-Oxide structure
3-Chloropyridine N-Oxide structure
Product Name:3-Chloropyridine N-Oxide
CAS No:1851-22-5
MF:C5H4ClNO
MW:129.544360160828
MDL:MFCD00128857
CID:205300
PubChem ID:123133
Update Time:2025-06-30

3-Chloropyridine N-Oxide Chemical and Physical Properties

Names and Identifiers

    • Pyridine, 3-chloro-,1-oxide
    • 3-Chloropyridine N-Oxide
    • 3-Chloropyridine n-oxide
    • 3-Chloropyridine-1-oxide
    • 3-chloro-1-oxidopyridin-1-ium
    • N-oxy-3-chloropyridine
    • 3-Chloro-pyridine1-oxide
    • 3-chloro-1-oxido-pyridin-1-ium
    • 3-chloro-1-oxidanidyl-pyridin-1-ium
    • Pyridine, 3-chloro-, 1-oxide (6CI,7CI,8CI,9CI)
    • 3-chloro-1$l^{5}-pyridin-1-one
    • MFCD00128857
    • AM86713
    • 5-chloropyridine N-oxide
    • Pyridine, 3-chloro-, 1-oxide
    • 3-Chloropyridine 1-oxide
    • 3-chloropyridin-1-ium-1-olate
    • NEXUNCTUUDERGR-UHFFFAOYSA-N
    • AS-14947
    • C2329
    • FT-0645949
    • EN300-156272
    • J-011867
    • DTXSID90171713
    • 3-Chloropyridine1-oxide
    • AKOS006273005
    • SY073799
    • 3-chloro-pyridine-N-oxide
    • SCHEMBL844033
    • 3-Chloropyridine-N-oxide
    • 3-chloro-pyridine 1-oxide
    • 3-chloro-pyridine-1-oxide
    • N10275
    • A812927
    • 1851-22-5
    • DB-000189
    • N-oxy-3-chloropyridine;3-Chloropyridine-1-oxide
    • pyridine 1-oxide, 3-chloro-
    • MDL: MFCD00128857
    • Inchi: 1S/C5H4ClNO/c6-5-2-1-3-7(8)4-5/h1-4H
    • InChI Key: NEXUNCTUUDERGR-UHFFFAOYSA-N
    • SMILES: ClC1=CC=C[N+](=C1)[O-]

Computed Properties

  • Exact Mass: 128.99800
  • Monoisotopic Mass: 128.998141
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 0
  • Hydrogen Bond Acceptor Count: 0
  • Heavy Atom Count: 8
  • Rotatable Bond Count: 0
  • Complexity: 78.8
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • Surface Charge: 0
  • Tautomer Count: nothing
  • XLogP3: nothing
  • Topological Polar Surface Area: 25.5

Experimental Properties

  • Density: 1.27
  • Melting Point: 56.0 to 60.0 deg-C
  • Boiling Point: 89°C/1mmHg(lit.)
  • Flash Point: 141.3°C
  • Refractive Index: 1.552
  • PSA: 25.46000
  • LogP: 1.76850
  • Vapor Pressure: 0.0±0.6 mmHg at 25°C

3-Chloropyridine N-Oxide Security Information

3-Chloropyridine N-Oxide Customs Data

  • HS CODE:2933399090
  • Customs Data:

    China Customs Code:

    2933399090

    Overview:

    2933399090. Other compounds with non fused pyridine rings in structure. VAT:17.0%. Tax refund rate:13.0%. Regulatory conditions:nothing. MFN tariff:6.5%. general tariff:20.0%

    Declaration elements:

    Product Name, component content, use to, Please indicate the appearance of Urotropine, 6- caprolactam please indicate the appearance, Signing date

    Summary:

    2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

3-Chloropyridine N-Oxide Pricemore >>

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3-Chloropyridine N-Oxide Production Method

3-Chloropyridine N-Oxide Related Literature

Additional information on 3-Chloropyridine N-Oxide

3-Chloropyridine N-Oxide: A Comprehensive Overview

3-Chloropyridine N-Oxide, also known by its CAS number CAS No. 1851-22-5, is a chemical compound that has garnered significant attention in the fields of organic chemistry, pharmacology, and materials science. This compound is a derivative of pyridine, a six-membered aromatic heterocycle, with a chlorine atom at the 3-position and an oxygen atom attached to the nitrogen atom in the ring. The structure of 3-Chloropyridine N-Oxide makes it a versatile molecule with potential applications in various industries.

The synthesis of 3-Chloropyridine N-Oxide typically involves oxidation reactions of pyridine derivatives. Recent studies have explored novel synthetic pathways that enhance the efficiency and scalability of its production. For instance, researchers have employed green chemistry principles to develop catalysts that facilitate the oxidation process under mild conditions, reducing environmental impact and cost. These advancements highlight the importance of sustainable practices in modern chemical synthesis.

In terms of physical properties, 3-Chloropyridine N-Oxide is known for its high stability under various conditions. Its melting point and solubility characteristics make it suitable for use in diverse chemical reactions. Recent research has also investigated its thermal stability and reactivity under different pH levels, providing valuable insights into its behavior in industrial processes.

The applications of 3-Chloropyridine N-Oxide span multiple domains. In pharmaceuticals, it serves as an intermediate in the synthesis of bioactive compounds with potential therapeutic effects. For example, studies have shown that derivatives of this compound exhibit anti-inflammatory and antioxidant properties, making them promising candidates for drug development.

In the agricultural sector, 3-Chloropyridine N-Oxide has been explored as a component in pesticides and herbicides. Its ability to interact with biological systems at molecular levels makes it effective in controlling pests and weeds without causing significant harm to the environment. Recent breakthroughs in nanotechnology have further enhanced its application by enabling targeted delivery systems that improve efficacy and reduce side effects.

The environmental impact of 3-Chloropyridine N-Oxide has also been a subject of scrutiny. Researchers have conducted extensive studies to assess its biodegradability and toxicity levels. Findings indicate that under controlled conditions, it degrades efficiently without leaving harmful residues, aligning with global efforts to promote eco-friendly chemical solutions.

In conclusion, 3-Chloropyridine N-Oxide, with its unique structure and versatile properties, continues to be a focal point in scientific research and industrial applications. As advancements in synthetic methods and application technologies unfold, this compound is poised to play an even more significant role in shaping the future of chemistry and related disciplines.

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