Production Method 1

573675-27-1

945557-04-0

Reaction Conditions

1.1 Reagents: Sodium nitrite ,  Hydrochloric acid Solvents: Water ;  1 h, 0 °C
1.2 Reagents: Copper ;  30 min, reflux
1.3 Reagents: Sodium hydroxide Solvents: Water ;  basified, cooled

Reference

Preparation of indole sulfonamides as modulators of progesterone receptors

, World Intellectual Property Organization, , ,

Production Method 2

573675-27-1

945557-04-0

Reaction Conditions

1.1 Reagents: Sodium nitrite ,  Hydrochloric acid Solvents: Water ;  cooled; 1 h, 0 - 5 °C
1.2 Reagents: Copper ;  1 h, reflux; cooled
1.3 Reagents: Water ;  cooled
1.4 Reagents: Sodium hydroxide Solvents: Water ;  basified

Reference

Preparation of pyrazole- and imidazole-carboxamide derivatives as modulators of androgen receptor

, World Intellectual Property Organization, , ,

5-Bromo-3-chloropyridine-2-carbonitrile Raw materials

• 3-amino-5-bromo-pyridine-2-carbonitrile

5-Bromo-3-chloropyridine-2-carbonitrile Preparation Products

• 5-Bromo-3-chloropyridine-2-carbonitrile (945557-04-0)

• 1. Embedding cyclic nitrone in mesoporous silica particles for EPR spin trapping of superoxide and other radicals?
  Eric Besson,Stéphane Gastaldi,Emily Bloch,Selma Aslan,Hakim Karoui,Olivier Ouari,Micael Hardy Analyst, 2019,144, 4194-4203
• 2. Dissolved oxygen sensor based on fluorescence quenching of oxygen-sensitive ruthenium complexes immobilized in sol–gel-derived porous silica coatings
  Analyst, 1996,121, 785-788
• 3. EWOD-driven droplet microfluidic device integrated with optoelectronic tweezers as an automated platform for cellular isolation and analysis?
  Gaurav J. Shah,Eric P.-Y. Chiou,Ming C. Wu,Chang-Jin “CJ” Kim Lab Chip, 2009,9, 1732-1739
• 4. Fast synthesis of copper nanoclusters through the use of hydrogen peroxide additive and their application for the fluorescence detection of Hg2+ in water samples?
  Liao Xiaoqing,Li Ruiyi,Li Zaijun,Sun Xiulan,Wang Zhouping,Liu Junkang New J. Chem., 2015,39, 5240-5248
• 5. Emulsifier-free, organotellurium-mediated living radical emulsion polymerization (emulsion TERP) of styrene: poly(dimethylaminoethyl methacrylate) macro-TERP agent?
  Yukiya Kitayama Polym. Chem., 2014,5, 2784-2792

• Solvents and Organic Chemicals Organic Compounds Organoheterocyclic compounds Pyridines and derivatives Halopyridines Polyhalopyridines

Market Research and Analysis of 5-Bromo-3-chloropyridine-2-carbonitrile in the Chemical-Biomedical Field

The compound 5-Bromo-3-chloropyridine-2-carbonitrile, identified by the CAS registry number 945557-04-0, has emerged as a significant molecule in the chemical-biomedical industry. This compound has garnered attention due to its potential applications in drug discovery, particularly in the development of novel therapeutic agents targeting various diseases, including cancer and infectious disorders.

Recent studies have highlighted the role of 5-Bromo-3-chloropyridine-2-carbonitrile as a promising lead compound in medicinal chemistry. Its unique structural features, including the bromine and chlorine substituents on the pyridine ring, contribute to its high reactivity and selectivity in biochemical reactions. These properties make it an ideal candidate for use in combinatorial chemistry and high-throughput screening processes.

Market demand for this compound has been driven by its increasing use in preclinical research and early-stage drug development. Major pharmaceutical companies and academic research institutions are actively exploring its potential as a building block for complex molecular architectures. Additionally, the compound's versatility in synthetic organic chemistry has expanded its utility across multiple therapeutic areas.

Global suppliers of 5-Bromo-3-chloropyridine-2-carbonitrile are strategically positioned to meet the growing demand from both industrial and academic sectors. Key players in this market are focusing on optimizing production processes to ensure high-quality standards while maintaining competitive pricing. The availability of this compound through various chemical suppliers has facilitated its widespread adoption in research laboratories worldwide.

In conclusion, 5-Bromo-3-chloropyridine-2-carbonitrile (CAS No. 945557-04-0) represents a valuable asset in the chemical-biomedical landscape. Its role as a versatile building block in drug discovery underscores its importance to both industry and academia. As research continues to uncover new applications for this compound, its market presence is expected to grow further, driven by advancements in synthetic methodologies and therapeutic innovations.

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