Efficient synthesis of 6,6′-diamido-2,2′-dipicolylamine ligands for potential phosphate anion sensing?
New Journal of Chemistry Pub Date: 2021-08-17 DOI: 10.1039/D1NJ03030B
Abstract
We report here the efficient synthesis of 6,6′-diamido-2,2′-dipicolylamines (DA-DPAs) which could be applied to phosphate anion sensing via pre-formed metal complexes. The design was based on the retrosynthetic analysis. This strategy enabled us to achieve the functionalized DA-DPAs in satisfactory yields with high purity using the Boekelheide rearrangement. Meanwhile, all the intermediates could be easily purified by silica gel column chromatography.
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Journal Name：New Journal of Chemistry
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CAS no.: 89640-58-4
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