- Rh-Catalyzed Hydrogenation of Amino Acids to Biobased Amino Alcohols: Tackling Challenging Substrates and Application to Protein HydrolysatesVandekerkhove, Annelies ; Claes, Laurens ; De Schouwer, Free; Van Goethem, Cedric ; Vankelecom, Ivo F. J.; et al, ACS Sustainable Chemistry & Engineering, 2018, 6(7), 9218-9228
Cas no 98-79-3 (L-Pyroglutamic acid)
L-Pyroglutamic acid is a naturally occurring amino acid that serves as an intermediate in glutathione biosynthesis. Its key advantages include improved skin hydration and enhanced moisturization due to its ability to improve humectancy and reduce trans-epidermal water loss. It also exhibits antioxidant properties, providing protection against oxidative stress and inflammation.
L-Pyroglutamic acid structure
Product Name:L-Pyroglutamic acid
CAS No:98-79-3
MF:C5H7NO3
MW:129.1140
MDL:MFCD00005272
CID:34979
PubChem ID:24898722
Update Time:2025-08-29
L-Pyroglutamic acid Chemical and Physical Properties
Names and Identifiers
-
- (S)-5-Oxopyrrolidine-2-carboxylic acid
- pidolic acid
- glutiminic acid
- 5-oxoproline
- Pyr-OH
- L-Pyroglutamic acid
- H-Pyr-OH
- L-2-Pyrrolidone-5-carboxylic acid
- (S)-(-)-2-Pyrrolidinone-5-carboxylic acid
- L-Pyrpglutamic Acid
- 5-Oxopyrrolidine-2-carboxylic acid
- 5-Pyrrolidone-2-carboxylic acid
- L-5-Pyrrolidone-2-carboxylic acid
- pyroglutamic acid
- Pyrrolidonecarboxylic Acid
- (S)-(-)-2-Pyrrolidone-5
- 5 oxoproline
- GlutaMic acid lactaM
- GlutiMic acid
- hydroxy-pyridin-3-yl-acetic acid
- L-5-Oxo-2-pyrrolidine carboxylic acid
- L-GlutiMinic acid
- α- AMinoglutaric acid lactaM
- L-Glutamic Acid Lactam
- (S)-2-Pyrrolidone-5-carboxylic Acid
- (S)-(-)-2-Pyrrolidone-5-carboxylic acid
- 5-oxo-L-proline
- (2S)-5-oxopyrrolidine-2-carboxylic acid
- L-5-Oxoproline
- L-Proline, 5-oxo-
- Pyroglutamate
- Proline, 5-oxo-
- 5-L-Oxoproline
- (S)-PYROGLUTAMIC ACID
- Pidolate
- 5-Carboxy-2-pyrrolidinone
- (-)-2-Pyrrolidone-5-carboxylic acid
- 2-Pyrrolidinone-5-carboxylic acid
- L-5-Carboxy-2-pyrrolidinone
- L-GLUTIMIN
- R-(+)-2-Pyrrolidinone-5-carboxylate
- 4042-36-8
- Glp
- MLS001304098
- 98-79-3
- 28874-51-3
- MLSMR
- 2-pyrrolidone-5-carboxylic acid
- 5-oxopyrrolidine-2-carboxylate
- 5-oxo-DL-proline
- SMR000112493
- 5-oxoprolinate anion
- L-Pyroglutamic acid,99%
-
- MDL： MFCD00005272
- Inchi： 1S/C5H7NO3/c7-4-2-1-3(6-4)5(8)9/h3H,1-2H2,(H,6,7)(H,8,9)/t3-/m0/s1
- InChI Key： ODHCTXKNWHHXJC-VKHMYHEASA-N
- SMILES： O=C1C([H])([H])C([H])([H])[C@@]([H])(C(=O)O[H])N1[H]
- BRN： 82132
Computed Properties
- Exact Mass: 129.04300
- Monoisotopic Mass: 129.042593
- Isotope Atom Count: 0
- Hydrogen Bond Donor Count: 2
- Hydrogen Bond Acceptor Count: 3
- Heavy Atom Count: 9
- Rotatable Bond Count: 1
- Complexity: 154
- Covalently-Bonded Unit Count: 1
- Defined Atom Stereocenter Count: 1
- Undefined Atom Stereocenter Count : 0
- Defined Bond Stereocenter Count: 0
- Undefined Bond Stereocenter Count: 0
- Topological Polar Surface Area: 66.4
- Surface Charge: 0
- Tautomer Count: 3
- XLogP3: -0.8
- Molecular Weight: 129.11
Experimental Properties
- Color/Form: Colorless crystals
- Density: 1.3816 (rough estimate)
- Melting Point: 155-162?°C
160-163?°C (lit.) - Boiling Point: 239.15°C (rough estimate)
- Flash Point: 227.8 °C
- Refractive Index: -10 ° (C=5, H2O)
- PH: 1.7 (50g/l, H2O, 20℃)
- Solubility: H2O: 1?M at?20?°C, clear, colorless
- Water Partition Coefficient: 10-15 g/100 mL (20 oC)
- Stability/Shelf Life: Stable. Incompatible with bases, acids, strong oxidizing agents.
- PSA: 66.40000
- LogP: -0.32160
- Merck: 8001
- pka: 3.32(at 25℃)
- Specific Rotation: -27.5 o (c=10, 1 N NaOH)
- Optical Activity: [α]20/D ?10.5±1°, c =?5% in H2O
- Solubility: Soluble in water, alcohol, acetone and glacial acetic acid, slightly soluble in ethyl acetate, insoluble in ether.
L-Pyroglutamic acid Security Information
-
Symbol:
- Prompt：warning
- Signal Word：Warning
- Hazard Statement： H315,H319,H335
- Warning Statement： P261,P305+P351+P338
- Hazardous Material transportation number：NONH for all modes of transport
- WGK Germany：3
- Hazard Category Code： 36/37/38
- Safety Instruction： S26-S36-S37/39
- FLUKA BRAND F CODES：21
- RTECS：TW3710000
-
Hazardous Material Identification：
- HazardClass：IRRITANT
- TSCA：Yes
- Storage Condition：Powder -20°C 3 years ? 4°C 2 years In solvent -80°C 6 months ? -20°C 1 month
- Risk Phrases：R36/37/38
L-Pyroglutamic acid Customs Data
- HS CODE：2933790090
- Customs Data：
China Customs Code:
2933790090Overview:
2933790090 Other lactams. VAT:17.0% Tax refund rate:9.0% Regulatory conditions:nothing MFN tariff:9.0% general tariff:20.0%
Declaration elements:
Product Name, component content, use to, Please indicate the appearance of Urotropine, 6- caprolactam please indicate the appearance, Signing date
Summary:
2933790090. other lactams. VAT:17.0%. Tax rebate rate:9.0%. . MFN tariff:9.0%. General tariff:20.0%
L-Pyroglutamic acid Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| CHENG DOU FEI BO YI YAO Technology Co., Ltd. | FB05468-1000g |
(2S)-5-oxopyrrolidine-2-carboxylic acid |
98-79-3 | 95% | 1000g |
$235 | 2023-09-07 | |
| XI GE MA AO DE LI QI （ SHANG HAI ） MAO YI Co., Ltd. | 1589029-30MG |
L-Pyroglutamic acid |
98-79-3 | 30mg |
￥4580.73 | 2025-01-11 | ||
| XI GE MA AO DE LI QI （ SHANG HAI ） MAO YI Co., Ltd. | Y0000123 |
L-Pyroglutamic acid |
98-79-3 | European Pharmacopoeia (EP) Reference Standard | ￥2654.27 | 2022-02-23 | ||
| TI XI AI ( SHANG HAI ) HUA CHENG GONG YE FA ZHAN Co., Ltd. | P0573-500G |
L-Pyroglutamic Acid |
98-79-3 | >97.0%(T) | 500g |
￥690.00 | 2024-04-15 | |
| SHANG HAI YI EN HUA XUE JI SHU Co., Ltd. | R010928-100g |
L-Pyroglutamic acid |
98-79-3 | 97% | 100g |
￥34 | 2024-07-19 | |
| SHANG HAI YI EN HUA XUE JI SHU Co., Ltd. | R010928-500g |
L-Pyroglutamic acid |
98-79-3 | 97% | 500g |
￥76 | 2024-07-19 | |
| SHANG HAI YI EN HUA XUE JI SHU Co., Ltd. | R010929-100g |
L-Pyroglutamic acid |
98-79-3 | 99% | 100g |
￥47 | 2024-07-19 | |
| SHANG HAI YI EN HUA XUE JI SHU Co., Ltd. | R010929-25g |
L-Pyroglutamic acid |
98-79-3 | 99% | 25g |
￥28 | 2024-07-19 | |
| SHANG HAI YI EN HUA XUE JI SHU Co., Ltd. | R010929-500g |
L-Pyroglutamic acid |
98-79-3 | 99% | 500g |
￥106 | 2024-07-19 | |
| SHANG HAI JI ZHI SHENG HUA Technology Co., Ltd. | H97940-500g |
L-Pyroglutamic acid |
98-79-3 | 500g |
￥108.0 | 2021-09-09 |
L-Pyroglutamic acid Production Method
Production Method 1
Reaction Conditions
1.1 Reagents: Hydrogen , Phosphoric acid Catalysts: Rhodium , Molybdenum oxide Solvents: Water ; 6 h, pH 1.8, 70 bar, 100 °C
Reference
L-Pyroglutamic acid Raw materials
L-Pyroglutamic acid Preparation Products
- (pyrrolidin-2-yl)methanol (498-63-5)
- pentan-2-amine (63493-28-7)
- 5-(Hydroxymethyl)pyrrolidin-2-one (62400-75-3)
- L-Pyroglutamic acid (98-79-3)
- 4-amino-5-hydroxypentanoic acid (40217-11-6)
- 4-Amino-1-pentanol (927-55-9)
- DL-2-Amino-1-pentanol (16369-14-5)
- 2-aminopentane-1,5-diol (21926-01-2)
- 2-Amino-5-hydroxypentanoic acid (533-88-0)
L-Pyroglutamic acid Suppliers
Tiancheng Chemical (Jiangsu) Co., Ltd
Gold Member
Audited Supplier
(CAS:98-79-3)(S)-(-)-2-Pyrrolidone-5-carboxylic acid
Order Number:LE2926;LE9076;LE27030457
Stock Status:in Stock
Quantity:25KG,200KG,1000KG
Purity:99%
Pricing Information Last Updated:Friday, 20 June 2025 11:43
Price ($):discuss personally
Email:[email protected]
Suzhou Senfeida Chemical Co., Ltd
Gold Member
Audited Supplier
(CAS:98-79-3)L-Pyroglutamic acid
Order Number:sfd20362
Stock Status:in Stock
Quantity:200kg
Purity:99.9%
Pricing Information Last Updated:Friday, 19 July 2024 14:38
Price ($):discuss personally
Email:[email protected]
L-Pyroglutamic acid Related Literature
-
J. Xu,T. J. Carrocci,A. A. Hoskins Chem. Commun., 2016,52, 549-552
-
Albertus D. Handoko,Khoong Hong Khoo,Teck Leong Tan,Hongmei Jin,Zhi Wei Seh J. Mater. Chem. A, 2018,6, 21885-21890
-
Olga Guselnikova,Gérard Audran,Jean-Patrick Joly,Andrii Trelin,Evgeny V. Tretyakov,Vaclav Svorcik,Oleksiy Lyutakov,Sylvain R. A. Marque Chem. Sci., 2021,12, 4154-4161
-
Hanie Hashtroudi,Ian D. R. Mackinnon J. Mater. Chem. C, 2020,8, 13108-13126
-
Partha Laskar,Christine Dufès Nanoscale Adv., 2021,3, 6007-6026
98-79-3 (L-Pyroglutamic acid) Related Products
- 85153-87-3(l-glutamic acid, compound with 5-oxo-dl-proline (1:1))
- 85153-23-7((2S)-2,6-Diaminohexanoic acid;5-oxopyrrolidine-2-carboxylic acid)
- 25501-47-7(L-Proline, 5-oxo-,ammonium salt (1:1))
- 645388-71-2(Proline, 5-oxo-, compd. with 1-tetradecanamine (1:1))
- 30657-38-6(L-Lysine, compd. with 5-oxo-L-proline (1:1))
- 645388-72-3(Proline, 5-oxo-, compd. with 1-hexadecanamine (1:1))
- 352431-30-2(DL-Pyroglutamic acid-d)
- 85200-40-4(bis(5-oxo-DL-prolinato-N1,O2)iron)
- 85136-49-8(tris(5-oxo-DL-prolinato-N1,O2)iron)
- 5497-58-5(Proline, 5-oxo-,ammonium salt (1:1))
Recommended suppliers
Tiancheng Chemical (Jiangsu) Co., Ltd
(CAS:98-79-3)(S)-(-)-2-Pyrrolidone-5-carboxylic acid
Purity:99%/99%/99%
Quantity:25KG,200KG,1000KG/25KG,200KG,1000KG/25KG,200KG,1000KG
Price ($):Inquiry/Inquiry/Inquiry
Suzhou Senfeida Chemical Co., Ltd
(CAS:98-79-3)L-Pyroglutamic acid
Purity:99.9%
Quantity:200kg
Price ($):Inquiry