- Preparation of salts and solvates of N-[3-[[[2-[(2,3-dihydro-2-oxo-1H-indol-5-yl)amino]-5-(trifluoromethyl)-4-pyrimidinyl]amino]methyl]-2-pyridinyl]-N-methylmethanesulfonamide for the treatment of abnormal cell growth., World Intellectual Property Organization, , ,
Cas no 98-11-3 (Phenylsulfonic Acid)
Phenylsulfonic acid is a strong organic acid characterized by the presence of a sulfonic acid group (–SO?H) attached to a phenyl ring. It is widely utilized as a catalyst, intermediate, or surfactant in organic synthesis, industrial processes, and specialty chemical applications. The compound exhibits high acidity, solubility in water and polar solvents, and thermal stability, making it suitable for acid-catalyzed reactions, esterifications, and polymerizations. Its aromatic structure allows for further functionalization, enabling tailored modifications in synthetic pathways. Phenylsulfonic acid is also employed in electroplating, dye production, and as a corrosion inhibitor. Proper handling is essential due to its corrosive nature.
Phenylsulfonic Acid structure
Product Name:Phenylsulfonic Acid
CAS No:98-11-3
MF:C6H6O3S
MW:158.175040721893
MDL:MFCD00011689
CID:34938
PubChem ID:7371
Update Time:2026-05-14
Phenylsulfonic Acid Chemical and Physical Properties
Names and Identifiers
-
- Benzenesulfonic acid
- BL70
- 17-120a
- acidebenzenesulfonique
- benzenemonosulfonicacid
- Besylic acid
- Kyselina benzensulfonova
- BENZENE SULFONIC ACID TECHNICAL GRADE
- BENZOLSULFONSAEURE
- Benzenesulfonic Acid Anhydrous
- Phenylsulfonic acid
- BSA
- Benzenesulfonic acid (surfactant)
- Benzenesulphonic acid
- Benzensulfonic acid
- Benzenemonosulfonic acid
- Benzenesulfonic acid 70%
- Benzene sulphonic acid
- Benzene sulfonic acid
- Kyselina benzensulfonova [Czech]
- SRSXLGNVWSONIS-UHFFFAOYSA-N
- 685928Z18A
- DSSTox_CID_4568
- DSSTox_RID_77453
- DSSTox_GSID_24568
- Benzenesulfonic acid, 90%, technical
- Blu-gard snitizing t
- Benzenesulfonic acid,95%
- Phenylsulfonic Acid
-
- MDL： MFCD00011689
- Inchi： 1S/C6H6O3S/c7-10(8,9)6-4-2-1-3-5-6/h1-5H,(H,7,8,9)
- InChI Key： SRSXLGNVWSONIS-UHFFFAOYSA-N
- SMILES： S(C1C([H])=C([H])C([H])=C([H])C=1[H])(=O)(=O)O[H]
- BRN： 0742513
Computed Properties
- Exact Mass: 158.00400
- Monoisotopic Mass: 158.003765
- Isotope Atom Count: 0
- Hydrogen Bond Donor Count: 1
- Hydrogen Bond Acceptor Count: 3
- Heavy Atom Count: 10
- Rotatable Bond Count: 1
- Complexity: 184
- Covalently-Bonded Unit Count: 1
- Defined Atom Stereocenter Count: 0
- Undefined Atom Stereocenter Count : 0
- Defined Bond Stereocenter Count: 0
- Undefined Bond Stereocenter Count: 0
- Topological Polar Surface Area: 54.4
- Surface Charge: 0
- XLogP3: 0
- Topological Polar Surface Area: 62.8
Experimental Properties
- Color/Form: Colorless needle or sheet crystals
- Density: 1.32
- Melting Point: 58.0 to 64.0 deg-C
- Boiling Point: 137℃
- Flash Point: Degrees Fahrenheit:>235.4°F
Degrees Celsius:>113°C - Refractive Index: 1.5151 (estimate)
- PH: 2 (H2O, 20℃)(saturated solution)
- Solubility: H2O: soluble0.1g/10 mL, clear, colorless
- Water Partition Coefficient: dissolution
- Stability/Shelf Life: Stable. Incompatible with strong oxidizing agents, bases, many organic compounds.
- PSA: 62.75000
- LogP: 2.01410
- Merck: 1070
- Sensitiveness: Hygroscopic
- pka: 0.7(at 25℃)
- FEMA: 2493
- Solubility: Soluble in water, soluble in ethanol, slightly soluble in benzene, insoluble in ether and carbon disulfide
- Vapor Pressure: No date available
Phenylsulfonic Acid Security Information
-
Symbol:
- Prompt：dangerous
- Signal Word：Danger
- Hazard Statement： H302,H314
- Warning Statement： P280,P305+P351+P338,P310
- Hazardous Material transportation number：UN 2583 8/PG 2
- WGK Germany：1
- Hazard Category Code： 34
- Safety Instruction： S26-S36/37/39-S45
- RTECS：DB4200000
-
Hazardous Material Identification：
- Packing Group：III
- Risk Phrases：R22; R34
- HazardClass：8
- TSCA：Yes
- PackingGroup：III
- Storage Condition：Keep container closed when not in use. Store in a cool, dry and well ventilated area, away from incompatible substances and corrosive substances
Phenylsulfonic Acid Customs Data
- HS CODE：29041000
- Customs Data：
China Customs Code:
2904100000Overview:
2904100000 Derivatives containing only sulfo groups and their salts and ethyl esters.Regulatory conditions:nothing.VAT:17.0%.Tax refund rate:9.0%.MFN tariff:5.5%.general tariff:30.0%
Declaration elements:
Product Name, component content, use to
Summary:
2904100000 derivatives containing only sulpho groups, their salts and ethyl esters.Supervision conditions:None.VAT:17.0%.Tax rebate rate:9.0%.MFN tariff:5.5%.General tariff:30.0%
Phenylsulfonic Acid Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| YUN NAN XI LI SHENG WU JI SHU GU FEN Co., Ltd. | BBP80122-5mg |
Benzenesulfonic acid |
98-11-3 | 98.0% | 5mg |
￥50 | 2021-05-07 | |
| NAN JING HUA XUE SHI JI GU FEN Co., Ltd. | C1030930323- 500ml（玻瓶） |
Phenylsulfonic Acid |
98-11-3 | 70% | 500ml |
￥ 191.8 | 2021-05-18 | |
| NAN JING HUA XUE SHI JI GU FEN Co., Ltd. | C1030930324- 500ml（塑瓶） |
Phenylsulfonic Acid |
98-11-3 | 70% | 500ml |
￥ 191.8 | 2021-05-18 | |
| NAN JING HUA XUE SHI JI GU FEN Co., Ltd. | C1040930035- 100ml |
Phenylsulfonic Acid |
98-11-3 | 70% | 100ml |
￥ 116.5 | 2021-05-18 | |
| NAN JING HUA XUE SHI JI GU FEN Co., Ltd. | C1040930023- 500ml（塑瓶） |
Phenylsulfonic Acid |
98-11-3 | 70% | 500ml |
￥ 305.9 | 2021-05-18 | |
| SHANG HAI A LA DING SHENG HUA KE JI GU FEN Co., Ltd. | B104130-100g |
Phenylsulfonic Acid |
98-11-3 | 98%, | 100g |
￥453.90 | 2023-09-04 | |
| SHANG HAI A LA DING SHENG HUA KE JI GU FEN Co., Ltd. | B104130-25g |
Phenylsulfonic Acid |
98-11-3 | 98%, | 25g |
￥144.90 | 2023-09-04 | |
| SHANG HAI A LA DING SHENG HUA KE JI GU FEN Co., Ltd. | B104130-5g |
Phenylsulfonic Acid |
98-11-3 | 98%, | 5g |
￥41.90 | 2023-09-04 | |
| Apollo Scientific | OR16405-500g |
Benzenesulphonic acid |
98-11-3 | 94% | 500g |
￡52.00 | 2023-09-01 | |
| Apollo Scientific | OR16405-2.5kg |
Benzenesulphonic acid |
98-11-3 | 94% | 2.5kg |
￡151.00 | 2023-09-01 |
Phenylsulfonic Acid Production Method
Production Method 1
Reaction Conditions
Reference
Production Method 2
Reaction Conditions
1.1 Reagents: N-Methyl-2-pyrrolidone , Oxygen Solvents: 1,2-Dichloroethane ; 1.5 h, 80 °C
Reference
- NMP-mediated chlorination of aliphatic alcohols with aryl sulfonyl chloride for the synthesis of alkyl chloridesZheng, Dagui; Mao, Liu-Liang; Zhu, Xian-Hong; Zhou, An-Xi, Synthetic Communications, 2018, 48(21), 2793-2800
Production Method 3
Reaction Conditions
1.1 Solvents: Ethanol ; 1.5 h, rt → 60 °C; 9 h, 60 °C; 60 °C → 41 °C
Reference
- Catalytic Enantioselective Hydrogenation of N-Alkoxycarbonyl Hydrazones: A Practical Synthesis of Chiral HydrazinesYoshikawa, Naoki; Tan, Lushi; McWilliams, J. Christopher; Ramasamy, Deepa; Sheppard, Ruth, Organic Letters, 2010, 12(2), 276-279
Phenylsulfonic Acid Raw materials
- 3-Bromobenzyl alcohol
- Phenylsulfonic Acid
- Hydrazinecarboxylic acid, 2-[(1S)-1-[4-(ethoxycarbonyl)phenyl]ethyl]-,1,1-dimethylethyl ester
Phenylsulfonic Acid Preparation Products
Phenylsulfonic Acid Suppliers
Suzhou Senfeida Chemical Co., Ltd
Gold Member
Audited Supplier
(CAS:98-11-3)Benzenesulfonic acid
Order Number:sfd10421
Stock Status:in Stock
Quantity:200kg
Purity:99.9%
Pricing Information Last Updated:Friday, 19 July 2024 14:35
Price ($):discuss personally
Email:[email protected]
Tiancheng Chemical (Jiangsu) Co., Ltd
Gold Member
Audited Supplier
(CAS:98-11-3)Benzenesulfonic acid
Order Number:LE5014
Stock Status:in Stock
Quantity:25KG,200KG,1000KG
Purity:99%
Pricing Information Last Updated:Friday, 20 June 2025 11:46
Price ($):discuss personally
Email:[email protected]
Phenylsulfonic Acid Related Literature
-
1. An autonomous self-optimizing flow machine for the synthesis of pyridine–oxazoline (PyOX) ligands?Eric Wimmer,Daniel Cortés-Borda,Solène Brochard,Elvina Barré,Charlotte Truchet,Fran?ois-Xavier Felpin React. Chem. Eng., 2019,4, 1608-1615
-
Kaiyuan Huang,Wangkang Qiu,Meilian Ou,Xiaorui Liu,Zenan Liao,Sheng Chu RSC Adv., 2020,10, 18824-18829
-
Philipp Traber,Stephan Kupfer,Stefanie Gr?fe,Isabelle Baussanne,Martine Demeunynck,Jean-Marie Mouesca,Serge Gambarelli,Vincent Artero,Murielle Chavarot-Kerlidou Chem. Sci., 2018,9, 4152-4159
-
L. Di Michele,D. Fiocco,F. Varrato,E. Eiser,G. Foffi Soft Matter, 2014,10, 3633-3648
98-11-3 (Phenylsulfonic Acid) Related Products
- 26158-00-9(Benzenesulfonic acid monohydrate)
- 3198-32-1(Benzenesulfonic acid,ion(1-))
- 39819-65-3(Nickel(II) Benzenesulfonate)
- 515-42-4(Sodium benzenesulfonate)
- 19402-64-3(Ammonium Benzenesulfonate)
- 31984-70-0(Benzenesulfonic acid,4-mercapto-, sodium salt (1:1))
- 1300-35-2(Benzenesulfonic acid,hydroxy-, aluminum salt (3:1))
- 31375-02-7(benzene-1,4-disulfonic acid)
- 22713-46-8(1,3-Benzenedisulfonicacid, ion(2-))
- 515-72-0(Benzenesulfonic acid,barium salt (2:1))
