- Preparation of salts and solvates of N-[3-[[[2-[(2,3-dihydro-2-oxo-1H-indol-5-yl)amino]-5-(trifluoromethyl)-4-pyrimidinyl]amino]methyl]-2-pyridinyl]-N-methylmethanesulfonamide for the treatment of abnormal cell growth., World Intellectual Property Organization, , ,
Cas no 717907-75-0 (PF-562271)
PF-562271 structure
Product Name:PF-562271
CAS No:717907-75-0
MF:C21H20F3N7O3S
MW:507.488812446594
MDL:MFCD17170115
CID:68682
PubChem ID:11713159
Update Time:2025-04-18
PF-562271 Chemical and Physical Properties
Names and Identifiers
-
- N-Methyl-N-[3-[[[2-[(2-oxo-2,3-dihydro-1H-indol-5-yl)amino]-5-trifluoromethylpyrimidin-4-yl]amino]methyl]pyridin-2-yl]methanesulfonamide
- PF-562271
- N-Methyl-N-(3-((2-(2-oxoindolin-5-ylamino)-5-(trifluoromethyl)pyrimidin-4-ylamino)methyl)pyridin-2-yl)methanesulfonamide
- N-methyl-N-[3-[[[2-[(2-oxo-1,3-dihydroindol-5-yl)amino]-5-(trifluoromethyl)pyrimidin-4-yl]amino]methyl]pyridin-2-yl]methanesulfonamide
- PF562271
- PROPAPGYL PF-562271
- n-methyl-n-(3-(((2-((2-oxo-2,3-dihydro-1h-indol-5-yl)amino)-5-trifluoromethylpyrimidin-4-yl)amino)methyl)pyridin-2-yl)methanesulfonamide
- PF-562271 FAK
- RTKS KINASE INHIBITOR
- K5BX8ZA7UF
- PF 562271
- C21H20F3N7O3S
- PF-00562271 free base
- SR-00000003721-2
- HMS3244L07
- BCP01852
- PF562271 besylate;PF 562271 besylate
- MLS006011245
- SMR004703004
- SR-00000003721
- AMY21304
- GTPL9381
- NSC754356
- HMS3265M11
- HMS3265M12
- MZDKLVOWGIOKTN-UHFFFAOYSA-N
- s2890
- NCGC00242495-01
- 717907-75-0
- BDBM50318884
- CCG-265006
- N-methyl-N-(3-(((2-((2-oxoindolin-5-yl)amino)-5-(trifluoromethyl)pyrimidin-4-yl)amino)methyl)pyridin-2-yl)methanesulfonamide
- HMS3651D06
- AKOS015904318
- NCGC00242495-18
- N-methyl-N-{3-[({2-[(2-oxo-2,3-dihydro-1H-indol-5-yl)amino]-5-(trifluoromethyl)pyrimidin-4-yl}amino)methyl]pyridin-2-yl}methanesulfonamide
- NSC-800849
- AS-16220
- HY-10459
- PF-562,271-26
- J-521695
- PF-562271; VS-6062
- Methanesulfonamide, n-[3-[[[2-[(2,3-dihydro-2-oxo-1h-indol-5-yl)amino]-5-(trifluoromethyl)-4-pyrimidinyl]amino]methyl]-2-pyridinyl]- n-methyl-
- UNII-K5BX8ZA7UF
- PF-562271 [WHO-SDG]
- SCHEMBL1206959
- HMS3244K08
- NSC800849
- 3bz3
- PF-562271 BESILATE
- BRD-K99545815-001-01-4
- PF-562,271
- HMS3244K07
- N-[3-[[[2-[(2,3-H-2-oxo-1H-indol-5-yl)amino]-5-(trifluoroMe)-4-pyrimidinyl]amino]Me]-2-pyridinyl]-N-Me-methanesulfonamide 95%
- PF-562271 free base
- EX-A1385
- CHEBI:91370
- MFCD16038299
- HMS3265N12
- AC-27466
- SW219484-2
- DTXSID10471000
- PF-562271- (FAK)
- 717907-75-0 (free base)
- Q27163236
- Methanesulfonamide, N-[3-[[[2-[(2,3-dihydro-2-oxo-1H-indol-5-yl)amino]-5-(trifluoromethyl)-4-pyrimidinyl]amino]methyl]-2-pyridinyl]-N-methyl
- FT-0711878
- Kinome_3857
- N-[3-[[[2-[(2,3-Dihydro-2-oxo-1H-indol-5-yl)amino]-5-(trifluoromethyl)-4-pyrimidinyl]amino]methyl]-2-pyridinyl]-N-methyl-methanesulfonamide
- N-methyl-N-[3-[[[2-[(2-oxo-1,3-dihydroindol-5-yl)amino]-5-(trifluoromethyl)-4-pyrimidinyl]amino]methyl]-2-pyridinyl]methanesulfonamide
- n-[3-[[[2-[(2,3-dihydro-2-oxo-1h-indol-5-yl)amino]-5-(trifluoromethyl)-4-pyrimidinyl]amino]methyl]-2-pyridinyl]-n-methylmethanesulfonamide
- BCPP000114
- CHEMBL1084546
- HMS3265N11
- NSC-754356
- SDCCGSBI-0654422.P001
- PF-562271?
- BRD-K99545815-074-03-7
- BRD-K99545815-001-06-3
- BRD-K99545815-074-02-9
- DTXCID40162555
- DTXCID20208905
- DTXSID40240064
- BRD-K99545815-003-01-0
- VS6062
- UNII-FK2M84H8UI
- N-Methyl-N-[3-[[[2-[(2-oxo-2,3-dihydro-1H-indol-5-yl)amino]-5-trifluoromethylpyrimidin-4-yl]amino]methyl]pyridin-2-yl]methanesulfonamide; PF-562271
- N-methyl-N-(3-(((2-((2-oxo-1,3-dihydroindol-5-yl)amino)-5-(trifluoromethyl)pyrimidin-4-yl)amino)methyl)pyridin-2-yl)methanesulfonamide
- PF-562271 (WHO-SDG)
- N-methyl-N-{3-[({2-[(2-oxo-1,3-dihydroindol-5-yl)amino]-5-(trifluoromethyl)pyrimidin-4-yl}amino)methyl]pyridin-2-yl}methanesulfonamide
- PF 562271 [WHO-DD]
-
- MDL： MFCD17170115
- Inchi： 1S/C21H20F3N7O3S/c1-31(35(2,33)34)19-12(4-3-7-25-19)10-26-18-15(21(22,23)24)11-27-20(30-18)28-14-5-6-16-13(8-14)9-17(32)29-16/h3-8,11H,9-10H2,1-2H3,(H,29,32)(H2,26,27,28,30)
- InChI Key： MZDKLVOWGIOKTN-UHFFFAOYSA-N
- SMILES： S(C)(N(C)C1C(=CC=CN=1)CNC1C(C(F)(F)F)=CN=C(N=1)NC1C=CC2=C(C=1)CC(N2)=O)(=O)=O
Computed Properties
- Exact Mass: 507.13000
- Monoisotopic Mass: 507.13004319g/mol
- Isotope Atom Count: 0
- Hydrogen Bond Donor Count: 3
- Hydrogen Bond Acceptor Count: 12
- Heavy Atom Count: 35
- Rotatable Bond Count: 7
- Complexity: 856
- Covalently-Bonded Unit Count: 1
- Defined Atom Stereocenter Count: 0
- Undefined Atom Stereocenter Count : 0
- Defined Bond Stereocenter Count: 0
- Undefined Bond Stereocenter Count: 0
- Topological Polar Surface Area: 138
- XLogP3: 2
Experimental Properties
- Color/Form: No data available
- Density: 1.540
- Melting Point: No data available
- Boiling Point: No data available
- Flash Point: No data available
- PSA: 140.82000
- LogP: 3.85020
PF-562271 Security Information
- Signal Word：Warning
- Hazard Statement： H302
- Warning Statement： P280-P305+P351+P338
- Safety Instruction： H303May be harmful if swallowed+H313Skin contact may be harmful+H333Inhalation may be harmful to the body
- Storage Condition：Powder -20°C 3 years ? 4°C 2 years In solvent -80°C 6 months ? -20°C 1 month
PF-562271 Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| SHANG HAI A LA DING SHENG HUA KE JI GU FEN Co., Ltd. | P126147-50mg |
PF-562271 |
717907-75-0 | ≥98% | 50mg |
￥956.90 | 2023-09-01 | |
| SHANG HAI A LA DING SHENG HUA KE JI GU FEN Co., Ltd. | P126147-5mg |
PF-562271 |
717907-75-0 | ≥98% | 5mg |
￥555.90 | 2023-09-01 | |
| SHANG HAI A LA DING SHENG HUA KE JI GU FEN Co., Ltd. | P126147-10mg |
PF-562271 |
717907-75-0 | ≥98% | 10mg |
￥864.90 | 2023-09-01 | |
| SHANG HAI A LA DING SHENG HUA KE JI GU FEN Co., Ltd. | P126147-100mg |
PF-562271 |
717907-75-0 | ≥98% | 100mg |
￥1529.90 | 2023-09-01 | |
| S e l l e c k ZHONG GUO | S2890-10mM (1mL in DMSO) |
PF-562271 |
717907-75-0 | 99.95% | 10mM (1mL in DMSO) |
￥2862.96 | 2023-09-15 | |
| S e l l e c k ZHONG GUO | S2890-5mg |
PF-562271 |
717907-75-0 | 99.95% | 5mg |
￥1392.84 | 2023-09-15 | |
| S e l l e c k ZHONG GUO | S2890-50mg |
PF-562271 |
717907-75-0 | 99.95% | 50mg |
￥5469.68 | 2023-09-15 | |
| SHANG HAI YI EN HUA XUE JI SHU Co., Ltd. | R031713-10mg |
PF-562271,98% |
717907-75-0 | 98% | 10mg |
￥1038 | 2024-05-22 | |
| SHANG HAI YI EN HUA XUE JI SHU Co., Ltd. | R031713-5mg |
PF-562271,98% |
717907-75-0 | 98% | 5mg |
￥667 | 2024-05-22 | |
| SHANG HAI YI EN HUA XUE JI SHU Co., Ltd. | R031713-50mg |
PF-562271,98% |
717907-75-0 | 98% | 50mg |
￥1148 | 2024-05-22 |
PF-562271 Production Method
Production Method 1
Reaction Conditions
Reference
PF-562271 Preparation Products
PF-562271 Suppliers
Amadis Chemical Company Limited
Gold Member
Audited Supplier
(CAS:717907-75-0)PF-562271
Order Number:A19408
Stock Status:in Stock
Quantity:10mg/50mg
Purity:99%
Pricing Information Last Updated:Friday, 30 August 2024 04:08
Price ($):189.0/585.0
Email:[email protected]
PF-562271 Related Literature
-
Yukiya Kitayama Polym. Chem., 2014,5, 2784-2792
-
Guang Xu,Wei Zhang,Ying Zhang,Xiaoxia Zhao,Ping Wen,Di Ma RSC Adv., 2018,8, 19353-19361
-
Partha Laskar,Christine Dufès Nanoscale Adv., 2021,3, 6007-6026
-
Thi Thu Tram Nguyen,Thanh Binh Nguyen Org. Biomol. Chem., 2021,19, 6015-6020
-
Christopher B. Rodell,Christopher B. Highley,Minna H. Chen,Neville N. Dusaj,Chao Wang,Lin Han,Jason A. Burdick Soft Matter, 2016,12, 7839-7847
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Recommended suppliers
Amadis Chemical Company Limited
(CAS:717907-75-0)PF-562271
Purity:99%/99%
Quantity:10mg/50mg
Price ($):189.0/585.0