Production Method 1

209256-55-3

95333-14-5

Reaction Conditions

1.1 Reagents: Dimethyl sulfoxide ,  Oxalyl chloride Solvents: Dichloromethane ;  -78 °C; 30 min, -78 °C
1.2 Reagents: Triethylamine ;  -78 °C

Reference

Preparation of benzofuran and dihydrobenzofuran melatonergic agents

, United States, , ,

Production Method 2

95333-14-5

Reaction Conditions

Reference

Preparation of tricyclic lactam compounds as glucose transport enhancers

, World Intellectual Property Organization, , ,

Production Method 3

95333-14-5

Reaction Conditions

Reference

Process for the preparation of symmetrical 4-(7'-benzofuryl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylates useful as calcium channel blockers and antihypertensives

, Spain, , ,

Production Method 4

95333-14-5

Reaction Conditions

Reference

Conformational analysis of organic carbonyl compounds. Part 4. A proton and carbon-13 nuclear magnetic resonance study of formyl and acetyl derivatives of benzo[b]furan

Benassi, Rois; Folli, Ugo; Iarossi, Dario; Schenetti, Luisa; Taddei, Ferdinando, Journal of the Chemical Society, 1984, (9), 1479-85

Production Method 5

209256-55-3

95333-14-5

Reaction Conditions

1.1 Reagents: Dimethyl sulfoxide ,  Oxalyl chloride Solvents: Dichloromethane ;  30 min, -78 °C
1.2 Reagents: Triethylamine ;  -78 °C; -78 °C → rt

Reference

Preparation of N-acyl-2-arylcyclopropylmethylamines as melatonergics

, World Intellectual Property Organization, , ,

Production Method 6

1388049-96-4

95333-14-5

Reaction Conditions

1.1 Reagents: Magnesium Catalysts: 1,2-Dibromoethane Solvents: Tetrahydrofuran ;  rt → reflux; 90 min, reflux; reflux → 0 °C
1.2 30 min, rt
1.3 Reagents: Monopotassium phosphate Solvents: Water ;  rt

Reference

Synthesis and pharmacological evaluation of N-benzyl substituted 4-bromo-2,5-dimethoxyphenethylamines as 5-HT2A/2C partial agonists

Hansen, Martin; Jacobsen, Stine Engesgaard; Plunkett, Shane; Liebscher, Gudrun Eckhard; McCorvy, John D.; et al, Bioorganic & Medicinal Chemistry, 2015, 23(14), 3933-3937

Production Method 7

863659-48-7

95333-14-5

Reaction Conditions

1.1 Catalysts: Grubbs second generation catalyst Solvents: Toluene ;  3 h, 90 °C

Reference

An isomerization-ring-closing metathesis strategy for the synthesis of substituted benzofurans

van Otterlo, Willem A. L.; Morgans, Garreth L.; Madeley, Lee G.; Kuzvidza, Samuel; Moleele, Simon S.; et al, Tetrahedron, 2005, 61(32), 7746-7755

Production Method 8

133720-60-2

95333-14-5

Reaction Conditions

1.1 Reagents: Magnesium Solvents: Tetrahydrofuran ;  rt → 50 °C; 30 min, reflux
1.2 Solvents: Tetrahydrofuran ;  25 °C; -78 °C; 1 h, 0 °C
1.3 Reagents: Ammonium chloride Solvents: Water

Reference

Preparation of 3-(indol-3-yl) 4-heteroaryl substituted pyrrole-2,5-diones as GSK-3β inhibitors

, World Intellectual Property Organization, , ,

Production Method 9

95333-14-5

Reaction Conditions

Reference

2-(Aminoethyl)benzofuran derivatives, preparation thereof, and therapeutic use as smooth muscle contractants

, World Intellectual Property Organization, , ,

Production Method 10

133720-60-2

128851-73-0

95333-14-5

123297-88-1

Reaction Conditions

1.1 Reagents: Butyllithium Solvents: Tetrahydrofuran ,  Hexane ;  -78 °C
1.2 -78 °C; 2 h, -78 °C
1.3 Solvents: Water ;  -78 °C

Reference

Spiro-oxadiazoline compounds as agonists of α-7-nicotinic acetylcholine receptors and their preparation

, World Intellectual Property Organization, , ,

Benzofuran-7-carbaldehyde Raw materials

• Benzaldehyde, 3-(1-propenyl)-2-(1-propenyloxy)-
• 7-iodo-1-benzofuran
• 7-Bromobenzofuran
• 6-bromo-1-benzofuran
• 7-Benzofuranmethanol

Benzofuran-7-carbaldehyde Preparation Products

• Benzofuran-6-carbaldehyde (123297-88-1)
• Benzofuran-7-carbaldehyde (95333-14-5)

• 1. Exchangeability of amino acid residues with similar physicochemical properties in coiled-coil interactions?
  Guiying Zhang,Maosheng Cheng,Yanni Li,Keliang Liu,Lifeng Cai Chem. Commun., 2013,49, 11086-11088
• 2. Evidence for the intrinsic nature of band-gap states electrochemically observed on atomically flat TiO2(110) surfaces?
  Shintaro Takata,Yoshihiro Miura Phys. Chem. Chem. Phys., 2014,16, 24784-24789
• 3. Emerging enantiomeric resolution materials with homochiral nano-fabrications
  Ji-Ping Wei Nanoscale, 2015,7, 11815-11832
• 4. Elusive 2-aminofuran Diels–Alder substrates for a straightforward synthesis of polysubstituted anilines?
  Ana G. Neo,Ana Bornadiego,Jesús Díaz,Stefano Marcaccini,Carlos F. Marcos Org. Biomol. Chem., 2013,11, 6546-6555
• 5. Fatty acid positional distribution in colostrum and mature milk of women living in Inner Mongolia, North Jiangsu and Guangxi of China?
  Long Deng,Qian Zou,Biao Liu,Wenhui Ye,Chengfei Zhuo,Li Chen,Ze-Yuan Deng,Ya-Wei Fan,Jing Li Food Funct., 2018,9, 4234-4245

• Solvents and Organic Chemicals Organic Compounds Organoheterocyclic compounds Benzofurans Benzofurans
• Solvents and Organic Chemicals Organic Compounds Organoheterocyclic compounds Benzofurans

• 917745-07-4(Methyl, 3-benzofuranyloxo-)
• 1136-77-2(Dibenzofuran,4,6-dimethyl-)
• 17059-52-8(7-Methylbenzofuran)
• 648449-50-7(3-Methyl-1-benzofuran-5-carbaldehyde)
• 75293-82-2(BenzBIndeno1,2-EPyran-6-Carboxaldehyde)
• 64965-91-9(Benzofuran,5,7-dimethyl-)
• 143883-36-7(3-Benzofurancarboxaldehyde,5-methyl-)
• 143883-37-8(3-Benzofurancarboxaldehyde,6-methyl-)
• 7320-53-8(Dibenzofuran, 4-methyl-)
• 96706-46-6(Dibenzob,dfuran-4-carbaldehyde)