- Modulation of estrogen-related receptors subtype selectivity: Conversion of an ERRβ/γ selective agonist to ERRα/β/γ pan agonistsShahien, Mohamed; Elagawany, Mohamed; Sitaula, Sadichha; Goher, Shaimaa S.; Burris, Sheryl L.; et al, Bioorganic Chemistry, 2020, 102,
Cas no 936-02-7 (benzoylhydrazine, O-hydroxy)
benzoylhydrazine, O-hydroxy structure
Product Name:benzoylhydrazine, O-hydroxy
CAS No:936-02-7
MF:C7H8N2O2
MW:152.150621414185
MDL:MFCD00007599
CID:40334
PubChem ID:13637
Update Time:2025-11-06
benzoylhydrazine, O-hydroxy Chemical and Physical Properties
Names and Identifiers
-
- Salicylhydrazide
- Salicylic acid hydrazide
- salicylic hydrazide
- Salicyloyl hydrazide
- salicylohydrazide
- 2-Hydroxybenzhydrazide
- o-Hydroxybenzoylhydrazine
- 2-Hydroxybenzoic hydrazide
- 2-hydroxybenzohydrazide
- 2-hydroxybenzene-1-carbohydrazide
- Propylenethiourea Solution
- Salicyl hydrazide
- Salicyloylhydrazine
- o-Hydroxybenzhydrazide
- o-Hydroxybenzoylhydrazide
- 2-Hydroxybenzoylhydrazide
- 2-Hydroxybenzoylhydrazine
- o-Hydroxylbenzhydrazide
- Salicyclohydrazine
- Salicoyl hydrazide
- o-Hydroxybenzoic acid hydrazide
- 2-Hydroxybenzoic acid hydrazide
- SALICYLIC ACID, HYDRAZIDE
- Salicycic acid hydrazide
- B
- Salicylic acid, hydrazide (6CI, 7CI, 8CI)
- 2-Hydroxybenzene-1-carbohydrazonic acid
- 2-Hydroxybenzenecarboxylic acid hydrazide
- 2-Hydroxybenzoyl hydrazide
- NSC 652
- o-Hydroxybenzohydrazide
- o-Hydroxybenzoic hydrazide
- o-Salicyloylhydrazide
- Ortho-hydroxybenzohydrazide
- S0242
- NSC652
- BRD-K80800852-001-01-8
- NS00039577
- CS-W004074
- SEW 04563
- HMS563E22
- Salicyloyl hydrazide, 98%
- MFCD00007599
- STR00212
- NSC-652
- Z57241860
- Maybridge1_007678
- Benzoic acid, 2-hydroxy-, hydrazide
- DTXSID0061321
- BBL008416
- SALICYLYL HYDRAZINE
- AKOS000120449
- InChI=1/C7H8N2O2/c8-9-7(11)5-3-1-2-4-6(5)10/h1-4,10H,8H2,(H,9,11
- EINECS 213-311-3
- SCHEMBL161525
- 2-Hydroxy-benzoic acid hydrazide
- CHEMBL170058
- salicyloylhydrazone
- R5T5F3Q8HR
- F1099-0053
- BDBM50056886
- salicoylhydrazine
- STK053411
- 936-02-7
- benzoylhydrazine, O-hydroxy
- DB-021200
- EN300-18163
- salicyclic acid hydrazide
-
- MDL： MFCD00007599
- Inchi： 1S/C7H8N2O2/c8-9-7(11)5-3-1-2-4-6(5)10/h1-4,10H,8H2,(H,9,11)
- InChI Key： XSXYESVZDBAKKT-UHFFFAOYSA-N
- SMILES： O=C(C1C(O)=CC=CC=1)NN
- BRN： 472355
Computed Properties
- Exact Mass: 152.05900
- Monoisotopic Mass: 152.059
- Isotope Atom Count: 0
- Hydrogen Bond Donor Count: 3
- Hydrogen Bond Acceptor Count: 3
- Heavy Atom Count: 11
- Rotatable Bond Count: 1
- Complexity: 149
- Covalently-Bonded Unit Count: 1
- Defined Atom Stereocenter Count: 0
- Undefined Atom Stereocenter Count : 0
- Defined Bond Stereocenter Count: 0
- Undefined Bond Stereocenter Count: 0
- XLogP3: 0.6
- Topological Polar Surface Area: 75.4
- Surface Charge: 0
- Tautomer Count: 14
Experimental Properties
- Color/Form: Not determined
- Density: 1.2804 (rough estimate)
- Melting Point: 148.0 to 152.0 deg-C
- Boiling Point: 274.61°C (rough estimate)
- Flash Point: °C
- Refractive Index: 1.5200 (estimate)
- PSA: 75.35000
- LogP: 1.08690
- Solubility: Not determined
benzoylhydrazine, O-hydroxy Security Information
-
Symbol:
- Prompt：warning
- Signal Word：Warning
- Hazard Statement： H315-H319
- Warning Statement： P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313
- WGK Germany：3
- Hazard Category Code： R36/37/38
- Safety Instruction： S26-S36
- RTECS：VO3700000
-
Hazardous Material Identification：
- HazardClass：IRRITANT
- TSCA：Yes
- Storage Condition：Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
- Risk Phrases：R36/37/38
benzoylhydrazine, O-hydroxy Customs Data
- HS CODE：2928000090
- Customs Data：
China Customs Code:
2928000090Overview:
2928000090 Other hydrazine(Hydrazine)And chlorhexidine(hydroxylamine)Organic derivatives of.Regulatory conditions:nothing.VAT:17.0%.Tax refund rate:9.0%.MFN tariff:6.5%.general tariff:20.0%
Declaration elements:
Product Name, component content, use to
Summary:
2928000090 other organic derivatives of hydrazine or of hydroxylamine VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:20.0%
benzoylhydrazine, O-hydroxy Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| SHANG HAI MAI KE LIN SHENG HUA Technology Co., Ltd. | H824753-500g |
2-hydroxybenzohydrazide |
936-02-7 | 98% | 500g |
2,927.00 | 2021-05-17 | |
| TI XI AI ( SHANG HAI ) HUA CHENG GONG YE FA ZHAN Co., Ltd. | S0242-25G |
Salicyl Hydrazide |
936-02-7 | >98.0%(T)(HPLC) | 25g |
￥400.00 | 2024-04-15 | |
| Fluorochem | 018713-1g |
2-Hydroxybenzhydrazide |
936-02-7 | 0.97 | 1g |
￡10.00 | 2022-03-01 | |
| Fluorochem | 018713-10g |
2-Hydroxybenzhydrazide |
936-02-7 | 0.97 | 10g |
￡11.00 | 2022-03-01 | |
| Fluorochem | 018713-25g |
2-Hydroxybenzhydrazide |
936-02-7 | 0.97 | 25g |
￡17.00 | 2022-03-01 | |
| Fluorochem | 018713-100g |
2-Hydroxybenzhydrazide |
936-02-7 | 0.97 | 100g |
￡52.00 | 2022-03-01 | |
| SHANG HAI JI ZHI SHENG HUA Technology Co., Ltd. | H36370-100g |
2-Hydroxybenzohydrazide |
936-02-7 | 98% | 100g |
￥140.0 | 2023-09-07 | |
| SHANG HAI JI ZHI SHENG HUA Technology Co., Ltd. | H36370-25g |
2-Hydroxybenzohydrazide |
936-02-7 | 98% | 25g |
￥37.0 | 2023-09-07 | |
| TRC | B443813-5g |
2-Hydroxybenzohydrazide |
936-02-7 | 5g |
$ 50.00 | 2022-06-07 | ||
| TRC | B443813-10g |
2-Hydroxybenzohydrazide |
936-02-7 | 10g |
$ 65.00 | 2022-06-07 |
benzoylhydrazine, O-hydroxy Production Method
Production Method 1
Reaction Conditions
1.1 Catalysts: Sulfuric acid Solvents: Methanol , Water ; 2 h, reflux; reflux → rt
1.2 Reagents: Hydrazine hydrate (1:1) ; 0 °C; 0 °C → rt; 1 - 2 h, reflux
1.2 Reagents: Hydrazine hydrate (1:1) ; 0 °C; 0 °C → rt; 1 - 2 h, reflux
Reference
Production Method 2
Reaction Conditions
1.1 Reagents: Hydrazine hydrate (1:1) Solvents: Methanol , Water ; 24 h, rt; cooled
1.2 Reagents: Hydrochloric acid Solvents: Water ; neutralized
1.2 Reagents: Hydrochloric acid Solvents: Water ; neutralized
Reference
- Pharmacological evaluation and preparation of nonsteroidal anti-inflammatory drugs containing an N-acyl hydrazone subunitFerreira de Melo, Thais Regina; Chelucci, Rafael Consolin; Pires, Maria Elisa Lopes; Dutra, Luiz Antonio; Barbieri, Karina Pereira; et al, International Journal of Molecular Sciences, 2014, 15(4), 5821-5837
Production Method 3
Reaction Conditions
1.1 Reagents: Hydrazine hydrate (1:1) Solvents: Ethanol
Reference
- Synthesis, crystal structure and theoretical computation of 2-hydroxybenzoic acid [(3-phenoxyphenyl)methylene]hydrazideYan, Hua; Yang, Jian-guo; Lin, Cai-ping; Pan, Fu-you, Huaxue Yanjiu Yu Yingyong, 2007, 19(1), 84-88
Production Method 4
Reaction Conditions
1.1 Reagents: Hydrazine hydrate (1:1) Solvents: Ethanol ; overnight, reflux
Reference
- Structural Investigations on Novel Non-Nucleoside Inhibitors of Human Norovirus PolymeraseGiancotti, Gilda ; Nannetti, Giulio ; Padalino, Gilda; Landini, Martina; Santos-Ferreira, Nanci ; et al, Viruses, 2023, 15(1),
Production Method 5
Reaction Conditions
1.1 Reagents: Thionyl chloride Solvents: Ethanol ; 4 h, 80 °C
1.2 Reagents: Hydrazine hydrate (1:1) ; 3 h, 80 °C
1.2 Reagents: Hydrazine hydrate (1:1) ; 3 h, 80 °C
Reference
- Studies on the synthesis of novel arylhydrazide type molecular tweezer artificial receptors in solvent-free conditions under microwave irradiation and its recognition propertiesShi, Peiyu; Zhao, Zhigang; Li, Xiaorui; Liu, Xingli, Youji Huaxue, 2010, 30(8), 1220-1225
Production Method 6
Reaction Conditions
1.1 Reagents: Hydrazine hydrate (1:1) Solvents: Methanol ; 5 h, 70 °C
Reference
- A photochromic salicylhydrazide based on perylene diimide and its application for ion sensor probesGu, Yu; Wang, Mingli; Nan, Yanxia; Yu, Gang; Lu, Yanbing ; et al, Journal of Luminescence, 2022, 241,
Production Method 7
Production Method 8
Reaction Conditions
1.1 Reagents: Hydrazine hydrate (1:1) Solvents: Methanol ; 12 h, reflux
Reference
- Molecular design and synthesis of novel salicyl glycoconjugates as elicitors against plant diseasesCui, Zining; Ito, Jun; Dohi, Hirofumi; Amemiya, Yoshimiki; Nishida, Yoshihiro, PLoS One, 2014, 9(9),
Production Method 9
Reaction Conditions
1.1 Reagents: Hydrazine hydrate (1:1) Solvents: Methanol ; 0 °C; 4 h, rt
Reference
- Development of phenyltriazole thiol-based derivatives as highly potent inhibitors of DCN1-UBC12 interactionZhou, Wenjuan; Xu, Chenhao; Dong, Guanjun; Qiao, Hui; Yang, Jing; et al, European Journal of Medicinal Chemistry, 2021, 217,
Production Method 10
Reaction Conditions
1.1 Reagents: Trifluoroacetic acid Solvents: Dichloromethane ; 1 h, rt
Reference
- Design, synthesis, and evaluation of novel small molecule inhibitors of the influenza virus protein NS1Jablonski, Joseph J.; Basu, Dipwanita; Engel, Daniel A.; Geysen, H. Mario, Bioorganic & Medicinal Chemistry, 2012, 20(1), 487-497
Production Method 11
Production Method 12
Reaction Conditions
1.1 Reagents: Hydrazine hydrate (1:1) ; 3 h, reflux
Reference
- Synthesis, spectral characterization, antimicrobial screening and DNA studies of transition metal complexes of Cu(II), Co(II), Ni(ii) and Zn(II) with heterocyclic triazol based derivativeSaravana Bhava, P.; Tharmaraj, P.; Muthuraj, V.; Umadevi, M., American Journal of PharmTech Research, 2013, 3(3), 511-529
Production Method 13
Reaction Conditions
1.1 Reagents: Hydrazine hydrate (1:1) Solvents: Ethanol ; 1 min; cooled
Reference
- Synthesis of 5-aryl-3-glycosylthio-4-phenyl-4H-1,2,4-triazoles and their acyclic analogs under conventional and microwave conditionsEl-Ashry, El Sayed H.; Rashed, Nagwa; Awad, Laila F.; Ramadan, El Sayed; Abdel-Maggeed, Somia M.; et al, Journal of Carbohydrate Chemistry, 2008, 27(2), 70-85
Production Method 14
Reaction Conditions
1.1 Reagents: Hydrazine hydrate (1:1) Solvents: Methanol ; 6 h, reflux
Reference
- Synthesis of novel benzohydrazone-oxadiazole hybrids as β-glucuronidase inhibitors and molecular modeling studiesTaha, Muhammad; Ismail, Nor Hadiani; Imran, Syahrul; Selvaraj, Manikandan; Rahim, Abdul; et al, Bioorganic & Medicinal Chemistry, 2015, 23(23), 7394-7404
Production Method 15
Production Method 16
Production Method 17
Production Method 18
Reaction Conditions
1.1 Reagents: Hydrazine hydrate (1:1) Solvents: Ethanol , Water ; 30 min, 25 °C
Reference
- Novel synthesis method of aromatic hydrazineTang, Xu-fu; Yang, Wen-qian; Teng, Zhen-zhen; Liu, Jian; Xie, Wen-lin, Hunan Keji Daxue Xuebao, 2013, 28(2), 107-109
Production Method 19
Reaction Conditions
1.1 Reagents: Hydrazine
Reference
- Heterocyclic syntheses with carbonic acid derivatives. III. 5-Substituted 2-amino-1,3,4-oxadiazole synthesesGlatt, H. H.; Bacaloglu, R.; Csunderlik, C.; Saleh, Sadiq A.; Szeibert, F.; et al, Buletinul Stiintific si Tehnic al Institutului Politehnic Traian Vuia Timisoara, 1981, 26(2), 111-16
Production Method 20
Reaction Conditions
1.1 Reagents: Hydrazine hydrate (1:1) Solvents: Ethanol ; overnight, rt → reflux
Reference
- Synthesis, structural characterization, and antimicrobial activity of novel ferrocene-N-acyl hydrazones designed by means of molecular simplification strategy Celebrating the 100th anniversary of the birth of Professor Paulo Freiredos Santos Filho, Jose Mauricio; de Souza Castro, Marcos Venicius Batista, Journal of Organometallic Chemistry, 2022, 979,
benzoylhydrazine, O-hydroxy Raw materials
- Ethyl salicylate
- Methyl salicylate
- 2-Hydroxybenzaldehyde
- Hydrazinecarboxylic acid, 2-(2-hydroxybenzoyl)-, 1,1-dimethylethyl ester
- 2-(1H-1,2,3-Benzotriazole-1-carbonyl)phenol
benzoylhydrazine, O-hydroxy Preparation Products
benzoylhydrazine, O-hydroxy Related Literature
-
Gerald J. Meyer,Leif Hammarstr?m Chem. Sci., 2020,11, 3460-3473
-
Weili Dai,Guangjun Wu,Michael Hunger Chem. Commun., 2015,51, 13779-13782
-
Dongjia Han,Bing Xue,Juan Du,Tomohiro Miyatake,Hitoshi Tamiaki,Xin Xing,Wei Yuan,Yanyan Li Phys. Chem. Chem. Phys., 2016,18, 24252-24260
-
M. Zeiger,N. J?ckel,P. Strubel,L. Borchardt,R. Reinhold,W. Nickel,J. Eckert,V. Presser,S. Kaskel J. Mater. Chem. A, 2015,3, 17983-17990
-
Jacob S. Jordan,Evan R. Williams Analyst, 2021,146, 2617-2625
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