- 7-[1H-Indol-2-yl]-2,3-dihydro-isoindol-1-ones as dual Aurora-A/VEGF-R2 kinase inhibitors: Design, synthesis, and biological activityHughes, Terry V.; Emanuel, Stuart L.; O'Grady, Harold R.; Connolly, Peter J.; Rugg, Catherine; et al, Bioorganic & Medicinal Chemistry Letters, 2008, 18(18), 5130-5133
Cas no 935269-27-5 (3-hydroxy-1H-isoindole-4-carboxylic acid)
935269-27-5 structure
Product Name:3-hydroxy-1H-isoindole-4-carboxylic acid
CAS No:935269-27-5
MF:C9H7NO3
MW:177.156782388687
MDL:MFCD11506114
CID:1039778
PubChem ID:44579994
Update Time:2024-10-26
3-hydroxy-1H-isoindole-4-carboxylic acid Chemical and Physical Properties
Names and Identifiers
-
- 2,3-dihydro-3-oxo-1H-Isoindole-4-carboxylic acid
- 3-Oxoisoindoline-4-carboxylic acid
- 3-oxo-1,2-dihydroisoindole-4-carboxylic acid
- 3-Oxo-2,3-dihydro-1H-isoindole-4-carboxylic acid
- 1H-Isoindole-4-carboxylic acid, 2,3-dihydro-3-oxo-
- SONYZPKBPBFLSS-UHFFFAOYSA-N
- 3-Oxo-4-isoindolinecarboxylic acid
- FCH890919
- 5877AC
- BDBM50264659
- OR305297
- SY235534
- ST24022972
- 2,3-Dihydro-3-oxo-1H-isoindole-4-carboxylic acid (ACI)
- 3-Oxoisoindoline-4-carboxylicacid
- 3-hydroxy-1H-isoindole-4-carboxylic acid
- 935269-27-5
- CHEMBL505379
- CS-0062203
- SCHEMBL5338831
- DS-3664
- Y10068
- DB-079603
- AKOS006323136
- Z1198323512
- MFCD11506114
- SB40069
- DTXSID60659558
- EN300-124506
-
- MDL： MFCD11506114
- Inchi： 1S/C9H7NO3/c11-8-7-5(4-10-8)2-1-3-6(7)9(12)13/h1-3H,4H2,(H,10,11)(H,12,13)
- InChI Key： SONYZPKBPBFLSS-UHFFFAOYSA-N
- SMILES： O=C(C1C2C(NCC=2C=CC=1)=O)O
Computed Properties
- Exact Mass: 177.042593085g/mol
- Monoisotopic Mass: 177.042593085g/mol
- Isotope Atom Count: 0
- Hydrogen Bond Donor Count: 2
- Hydrogen Bond Acceptor Count: 3
- Heavy Atom Count: 13
- Rotatable Bond Count: 1
- Complexity: 251
- Covalently-Bonded Unit Count: 1
- Defined Atom Stereocenter Count: 0
- Undefined Atom Stereocenter Count : 0
- Defined Bond Stereocenter Count: 0
- Undefined Bond Stereocenter Count: 0
- Topological Polar Surface Area: 66.4
- XLogP3: 0.3
3-hydroxy-1H-isoindole-4-carboxylic acid Security Information
- Signal Word：Warning
- Hazard Statement： H302
- Warning Statement： P280-P305+P351+P338
- Storage Condition：Sealed in dry,Room Temperature
3-hydroxy-1H-isoindole-4-carboxylic acid Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| Fluorochem | 221416-250mg |
3-Oxoisoindoline-4-carboxylic acid |
935269-27-5 | 95% | 250mg |
￡115.00 | 2022-03-01 | |
| Fluorochem | 221416-1g |
3-Oxoisoindoline-4-carboxylic acid |
935269-27-5 | 95% | 1g |
￡331.00 | 2022-03-01 | |
| TRC | O991500-10mg |
3-Oxoisoindoline-4-carboxylic Acid |
935269-27-5 | 10mg |
$ 50.00 | 2022-06-03 | ||
| TRC | O991500-50mg |
3-Oxoisoindoline-4-carboxylic Acid |
935269-27-5 | 50mg |
$ 135.00 | 2022-06-03 | ||
| TRC | O991500-100mg |
3-Oxoisoindoline-4-carboxylic Acid |
935269-27-5 | 100mg |
$ 230.00 | 2022-06-03 | ||
| SHANG HAI JI ZHI SHENG HUA Technology Co., Ltd. | O30620-250mg |
3-Oxoisoindoline-4-carboxylic acid |
935269-27-5 | 250mg |
￥886.0 | 2021-09-04 | ||
| SHANG HAI JI ZHI SHENG HUA Technology Co., Ltd. | O30620-1g |
3-Oxoisoindoline-4-carboxylic acid |
935269-27-5 | 1g |
￥3126.0 | 2021-09-04 | ||
| SHANG HAI JI ZHI SHENG HUA Technology Co., Ltd. | O30620-5g |
3-Oxoisoindoline-4-carboxylic acid |
935269-27-5 | 5g |
￥12876.0 | 2021-09-04 | ||
| SHANG HAI JI ZHI SHENG HUA Technology Co., Ltd. | O30620-100mg |
3-Oxoisoindoline-4-carboxylic acid |
935269-27-5 | 100mg |
￥576.0 | 2021-09-04 | ||
| ChemScence | CS-0062203-100mg |
3-Oxoisoindoline-4-carboxylic acid |
935269-27-5 | 95.88% | 100mg |
$75.0 | 2022-04-26 |
3-hydroxy-1H-isoindole-4-carboxylic acid Production Method
Production Method 1
Reaction Conditions
1.1 Reagents: Lithium hydroxide Solvents: Methanol , Tetrahydrofuran , Water ; 25 °C
Reference
Production Method 2
Reaction Conditions
1.1 Reagents: Lithium hydroxide Solvents: Methanol , Tetrahydrofuran , Water ; reflux
Reference
- Substituted dihydroisoindolones, processes for preparing them, pharmaceutical compositions containing them, and their use as protein kinase inhibitors, World Intellectual Property Organization, , ,
3-hydroxy-1H-isoindole-4-carboxylic acid Raw materials
3-hydroxy-1H-isoindole-4-carboxylic acid Preparation Products
3-hydroxy-1H-isoindole-4-carboxylic acid Related Literature
-
Chandran Rajendran,Govindaswamy Satishkumar,Charlotte Lang,Eric M. Gaigneaux Catal. Sci. Technol., 2020,10, 2583-2592
-
J. M. Granadino-Roldán,M. Fernández-Gómez,A. Navarro,T. Pe?a Ruiz,U. A. Jayasooriya Phys. Chem. Chem. Phys., 2004,6, 1133-1143
-
José M. Rivera,Mariana Martín-Hidalgo,Jean C. Rivera-Ríos Org. Biomol. Chem., 2012,10, 7562-7565
935269-27-5 (3-hydroxy-1H-isoindole-4-carboxylic acid) Related Products
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- 77960-29-3(1H-Isoindole-4-carboxylic acid, 2,3-dihydro-3-oxo-2-(phenylmethyl)-)
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- 20262-55-9(1,3-Dioxoisoindoline-5-carboxylic acid)
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- 62554-97-6(Benzoic acid,2,2'-[1,2-ethanediylbis(iminocarbonyl)]bis- (9CI))
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