Production Method 1

934-74-7

Reaction Conditions

1.1 Reagents: Potassium hydroxide ,  Hydrazine hydrate (1:1) Solvents: Triethylene glycol

Reference

Anisotropy effects of conjugated cyclic systems. VI. Structure and magnetic anisotropy of mesityl-substituted ferrocenes

Fuchs, Bernhard; Froehlich, Roland; Musso, Hans, Chemische Berichte, 1985, 118(5), 1968-82

Production Method 2

934-74-7

Reaction Conditions

1.1 Reagents: Aluminum chloride

Reference

Composition of products of the alkylation of xylenes by ethyl chloride in the presence of aluminum chloride

Babin, E. P.; Lozovoi, V. I.; Krasnoshchek, A. P.; Kurilo, L. I.; Begunov, N. A., Voprosy Khimii i Khimicheskoi Tekhnologii, 1979, 54, 36-9

Production Method 3

934-74-7

Reaction Conditions

Reference

Arene-metal complexes. 13. Reaction of substituted (benzene)tricarbonylchromium complexes with n-butyllithium

Card, Roger J.; Trahanovsky, Walter S., Journal of Organic Chemistry, 1980, 45(13), 2560-6

Production Method 4

934-74-7

Reaction Conditions

Reference

Preparation of aromatics over zeolite catalysts

, United States, , ,

Production Method 5

934-74-7

Reaction Conditions

1.1 Reagents: Butyllithium ,  Potassium tert-butoxide Solvents: Pentane
1.2 Solvents: Tetrahydrofuran

Reference

Delocalized carbanions: 3,3',5,5'-tetramethylenebiphenyl tetraanion, a new tetraanion

Gordon, Bernard III; Loftus, James E., Journal of Organic Chemistry, 1986, 51(9), 1618-20

Production Method 6

9005-53-2

934-74-7

88-60-8

87-85-4

2219-78-5

1758-88-9

13037-79-1

15181-13-2

13632-94-5

876-20-0

622-96-8

Reaction Conditions

1.1 Reagents: Hydrogen Catalysts: Palladium ,  Chromium chloride (CrCl3) Solvents: Methanol ;  4 h, 2 MPa, 280 °C

Reference

Insight into the solvent, temperature and time effects on the hydrogenolysis of hydrolyzed lignin

Shu, Riyang; Zhang, Qi; Ma, Longlong; Xu, Ying; Chen, Pengru; et al, Bioresource Technology, 2016, 221, 568-575

Production Method 7

934-74-7

Reaction Conditions

1.1 Reagents: Hydrofluoric acid Catalysts: Boron trifluoride ;  1 h, 62 °C

Reference

Ethylene

Crimmins, Michael T.; Kim-Meade, Agnes S., e-EROS Encyclopedia of Reagents for Organic Synthesis, 2001, 1, 1-4

Production Method 8

934-74-7

Reaction Conditions

Reference

Alkylation and transalkylation reactions of aromatic hydrocarbons. V. Ethylation and transethylation of naphthalene

Shimada, Keizo; Nagahama, Shizuo, Bulletin of the Chemical Society of Japan, 1975, 48(11), 3306-8

Production Method 9

934-74-7

Reaction Conditions

Reference

Reactions of phosphorus esters with dialkylbenzenes in the presence of aluminum chloride. New Method for the selective synthesis of 1,2,4- and 1,3,5-isomers

Sosnovsky, G.; Shende, M. W., Synthesis, 1972, (8), 423-6

Production Method 10

934-74-7

Reaction Conditions

1.1 Reagents: Isopropanol Catalysts: Magnesium oxide ;  673 K

Reference

Catalytic hydrogen transfer over magnesia

Glinski, Marek, Applied Catalysis, 2008, 349(1-2), 133-139

Production Method 11

934-74-7

1758-88-9

874-41-9

Reaction Conditions

1.1 Catalysts: Alumina ,  Silica ;  2.5 MPa, 210 °C

Reference

Preparation of 4-ethyl-m-xylene from its isomer mixtures

, Japan, , ,

Production Method 12

934-74-7

90-00-6

581-42-0

496-11-7

575-37-1

527-53-7

17059-52-8

768-49-0

3454-07-7

611-15-4

622-96-8

Reaction Conditions

1.1 500 °C

Reference

Acetic acid conversion reactions on basic and acidic catalysts under biomass fast pyrolysis conditions

Psarras, A. C.; Michailof, C. M.; Iliopoulou, E. F.; Kalogiannis, K. G.; Lappas, A. A.; et al, Molecular Catalysis, 2019, 465, 33-42

1-Ethyl-3,5-dimethylbenzene Raw materials

• Lignin

1-Ethyl-3,5-dimethylbenzene Preparation Products

• 2-tert-butyl-5-methylphenol (88-60-8)
• 2-Ethylphenol (90-00-6)
• 2,6-Dimethylnaphthalene (581-42-0)
• Indane (496-11-7)
• 1,7-Dimethylnaphthalene (575-37-1)
• Hexamethylbenzene (87-85-4)
• Phenol,2-ethyl-4,5-dimethyl- (2219-78-5)
• 1,2,3,5-Tetramethylbenzene (527-53-7)
• 2-Ethyl-1,4-dimethylbenzene (1758-88-9)
• Phenol,2-(1,1-dimethylethyl)-3-methyl- (13037-79-1)
• Benzene,1-ethyl-3,5-bis(1-methylethyl)- (15181-13-2)
• Benzene,1,4-diethyl-2-methyl- (13632-94-5)
• 7-Methylbenzofuran (17059-52-8)
• 2-Phenylethyl-1,1,2,2-d4-amine (876-20-0)
• 1-Ethyl-2,4-dimethylbenzene (874-41-9)
• 2-Methyl-1-phenyl-1-propene (>85%) (768-49-0)
• 1-Ethyl-4-vinylbenzene (>80%) (3454-07-7)
• 2-Methylstyrene (611-15-4)
• 4-Ethyltoluene (622-96-8)

• 1. Ester-mediated peptide formation promoted by deep eutectic solvents: a facile pathway to proto-peptides?
  Chen-Yu Chien,Sheng-Sheng Yu Chem. Commun., 2020,56, 11949-11952
• 2. Emerging investigator series: bacteriophages as nano engineering tools for quality monitoring and pathogen detection in water and wastewater
  Fereshteh Bayat Environ. Sci.: Nano, 2021,8, 367-389
• 3. Fe(iii)-mediated isomerization of α,α-diarylallylic alcohols to ketones via radical 1,2-aryl migration?
  Ziyang Deng,Changwei Chen,Sunliang Cui RSC Adv., 2016,6, 93753-93755
• 4. Examination of deposit in commercial diluted phosphoric acid
  Analyst, 1880,5, 146-147
• 5. Excited state potential energy surfaces and their interactions in FeIVO active sites
  Shaun D. Wong,Edward I. Solomon Dalton Trans., 2014,43, 17567-17577

• Solvents and Organic Chemicals Organic Compounds Benzenoids Benzene and substituted derivatives m-Xylenes
• Solvents and Organic Chemicals Organic Compounds Benzenoids Benzene and substituted derivatives Xylenes m-Xylenes
• Solvents and Organic Chemicals Organic Compounds Hydrocarbons

1-Ethyl-3,5-Dimethylbenzene (CAS No. 934-74-7): A Comprehensive Overview

1-Ethyl-3,5-dimethylbenzene, also known by its CAS registry number CAS No. 934-74-7, is an aromatic hydrocarbon derivative with a unique structure that makes it a valuable compound in various industrial and chemical applications. This compound belongs to the family of substituted benzenes, where the benzene ring is substituted with an ethyl group at position 1 and methyl groups at positions 3 and 5. The molecular formula of this compound is C₁₁H₁₆, and its molecular weight is approximately 156.25 g/mol.

The synthesis of 1-Ethyl-3,5-dimethylbenzene typically involves Friedel-Crafts alkylation or acylation reactions, which are well-established methods for introducing alkyl groups onto aromatic rings. Recent advancements in catalytic systems have enabled more efficient and selective syntheses, reducing byproducts and improving yield. For instance, the use of solid acid catalysts or zeolites has been reported to enhance the reaction efficiency in Friedel-Crafts alkylation processes.

In terms of physical properties, 1-Ethyl-3,5-dimethylbenzene is a colorless liquid with a characteristic aromatic odor. Its boiling point is around 160°C, and it has a density of approximately 0.88 g/cm3 at room temperature. The compound is sparingly soluble in water but miscible with organic solvents such as ethanol, ether, and chloroform. Its chemical stability makes it suitable for use in various industrial processes without significant degradation under normal operating conditions.

The applications of CAS No. 934-74-7 are diverse and span across multiple industries. It is widely used as a solvent in the pharmaceutical and chemical industries due to its ability to dissolve a wide range of organic compounds. Additionally, it serves as an intermediate in the synthesis of more complex organic molecules, including pharmaceuticals, agrochemicals, and specialty chemicals.

In the field of materials science, recent studies have explored the use of 1-Ethyl-3,5-dimethylbenzene as a precursor for the synthesis of advanced materials such as carbon nanotubes and graphene derivatives. For example, researchers have reported that this compound can act as a carbon source in chemical vapor deposition (CVD) processes under specific conditions.

The environmental impact of CAS No. 934-74-7 has also been a subject of recent research interest. Studies have shown that this compound undergoes biodegradation under aerobic conditions, with microbial communities playing a significant role in its breakdown. However, its persistence in aquatic environments remains a concern due to its relatively low solubility in water.

In terms of safety considerations, handling 1-Ethyl-3,5-dimethylbenzene requires adherence to standard laboratory practices to minimize exposure risks. It is important to note that while this compound is not classified as hazardous under normal conditions, prolonged exposure may cause irritation to the eyes and skin.

In conclusion, CAS No. 934-74-7, or 1-Ethyl-3,5-dimethylbenzene, is a versatile compound with significant applications across various industries. Its unique chemical properties and ease of synthesis make it an essential building block in organic chemistry. As research continues to uncover new applications and improve synthesis methods, this compound will likely remain an important component in both academic and industrial settings.

• 141-93-5(1,3-DIETHYLBENZENE)
• 2618-00-0(Ethyl-β,β,β-d3-benzene)
• 620-14-4(3-Ethyltoluene)
• 622-96-8(4-Ethyltoluene)
• 17203-53-1(Ethyl, 2-phenyl-)
• 102-25-0(1,3,5-Triethylbenzene)
• 25837-05-2(Ethylbenzene-d10)
• 25340-17-4(Diethylbenzene)
• 287399-32-0(Ethyl-α-13C-benzene)
• 1861-01-4(Ethyl-α,α-d2-benzene)