Production Method 1

120-14-9

93-03-8

Reaction Conditions

1.1 Reagents: Diphenylsilane Catalysts: Calcium oxide Solvents: Dimethyl sulfoxide ;  5 - 240 min, 25 - 100 °C
1.2 Reagents: Water

Reference

Green preparation of biomass-based aromatic alcohols

, China, , ,

Production Method 2

120-14-9

93-03-8

Reaction Conditions

1.1 Reagents: Hydrogen Catalysts: Nickel Solvents: Ethanol

Reference

New spasmolytic derivatives of 1-phenylisoquinoline

Tsatsas, Georges, Annales Pharmaceutiques Francaises, 1952, 10, 276-91

Production Method 3

120-14-9

93-03-8

Reaction Conditions

1.1 Reagents: Sodium formate Catalysts: Iridium(2+), chloro(1,10-phenanthroline-κN1,κN10)(2,2′:6′,2′′-terpyridine-κN1,κN… Solvents: Ethanol ,  Water ;  45 min, 100 °C

Reference

Polypyridyl iridium(III) based catalysts for highly chemoselective hydrogenation of aldehydes

Pandrala, Mallesh; Resendez, Angel; Malhotra, Sanjay V., Journal of Catalysis, 2019, 378, 283-288

Production Method 4

120-14-9

93-03-8

Reaction Conditions

1.1 Catalysts: Palladium ,  Titanium Solvents: Methanol ;  10 min, 35 °C
1.2 Reagents: Hydrogen ;  5 h, 0.4 MPa, 45 °C; 2 h, 45 °C

Reference

Cost-effective preparation method of veratryl alcohol

, China, , ,

Production Method 5

120-14-9

93-03-8

Reaction Conditions

1.1 Reagents: Isopropanol Catalysts: Montmorillonite ((Al1.33-1.67Mg0.33-0.67)(Ca0-1Na0-1)0.33Si4(OH)2O10.xH2O) ;  5 h, 1 MPa, 100 °C

Reference

Strong Oxophilicity of Zr Species in Zr4+-Exchanged Montmorillonite Boosted Meerwein-Ponndorf-Verley Reduction of Renewable Carbonyl Compounds

Song, Jinliang ; Xie, Chao ; Xue, Zhimin ; Wang, Tiejun, ACS Sustainable Chemistry & Engineering, 2022, 10(37), 12197-12206

Production Method 6

120-14-9

93-03-8

Reaction Conditions

1.1 Reagents: Sodium borohydride Solvents: Methanol ;  6 h, 0 °C
1.2 Solvents: Water

Reference

Synthesis of (+)-salvianolic acid A from sodium Danshensu

Xu, Kai; Liu, Hao; Liu, Delong; Sheng, Cheng; Shen, Jiefeng; et al, Tetrahedron, 2018, 74(40), 5996-6002

Production Method 7

120-14-9

93-03-8

Reaction Conditions

1.1 Reagents: Hydrogen Catalysts: Nickel (Palladium bimetallic catalyst) ,  Palladium (Nickel bimetallic catalyst) Solvents: Methanol ;  4.1 h, rt

Reference

Highly chemoselective hydrogenation of active benzaldehydes to benzyl alcohols catalyzed by bimetallic nanoparticles

Liu, Chulong; Bao, Hailin; Wang, Dingsheng; Wang, Xinyan; Li, Yadong; et al, Tetrahedron Letters, 2015, 56(46), 6460-6462

Production Method 8

120-14-9

93-03-8

Reaction Conditions

1.1 Reagents: Sodium borohydride ;  10 min, rt
1.2 Reagents: Sodium bicarbonate Solvents: Water ;  rt

Reference

Synthesis and heme polymerization inhibitory activity (HPIA) assay of antiplasmodium of N-(3,4-dimethoxybenzyl)-1,10-phenanthrolinium bromide from vanillin

Fitriastuti, Dhina; Mardjan, Muhammad Idham Darussalam; Jumina; Mustofa, Indonesian Journal of Chemistry, 2014, 14(1), 1-6

Production Method 9

120-14-9

93-03-8

Reaction Conditions

1.1 Reagents: Sodium borohydride Solvents: Methanol ;  0 °C; 3 h, 0 °C

Reference

Electrochemical Cleavage of Aryl Ethers Promoted by Sodium Borohydride

Wu, Wen-Bin; Huang, Jing-Mei, Journal of Organic Chemistry, 2014, 79(21), 10189-10195

Production Method 10

120-14-9

93-03-8

Reaction Conditions

1.1 Reagents: Sodium borohydride Solvents: Methanol ;  0 °C; 20 min, 0 °C
1.2 Reagents: Hydrochloric acid Solvents: Water ;  neutralized

Reference

New method of preparation of (2-bromo-4,5-dimethoxyphenyl)propanenitrile by reaction of 1-bromo-2-(bromomethyl)-4,5-dimethoxybenzene with acetonitrile and its use for the synthesis of ivabradine and its pharmaceutically acceptable acid addition salts

, European Patent Organization, , ,

Production Method 11

494-99-5

93-03-8

Reaction Conditions

1.1 Reagents: Isopropanol Catalysts: Palladium diacetate ;  0.5 h, 1.5 MPa, 180 °C

Reference

Method for catalytic conversion of veratryl alcohol into 3,4-dimethoxytoluene

, China, , ,

Production Method 12

120-14-9

93-03-8

Reaction Conditions

1.1 Reagents: Sodium borohydride Solvents: Methanol ;  0 °C

Reference

FeCl3-Catalyzed Self-Cleaving Deprotection of Methoxyphenylmethyl-Protected Alcohols

Sawama, Yoshinari; Masuda, Masahiro; Asai, Shota; Goto, Ryota; Nagata, Saori; et al, Organic Letters, 2015, 17(3), 434-437

Production Method 13

120-14-9

93-03-8

Reaction Conditions

1.1 Reagents: Tributylstannane Catalysts: Phenylboronic acid Solvents: Dichloromethane

Reference

Arylboronic acid-facilitated selective reduction of aldehydes by tributyltin hydride

Yu, Hongwu; Wang, Binghe, Synthetic Communications, 2001, 31(17), 2719-2725

Production Method 14

120-14-9

93-03-8

Reaction Conditions

1.1 Reagents: Sodium bicarbonate Solvents: Methanol ;  1 h, rt
1.2 Reagents: Ammonium chloride Solvents: Water

Reference

Evaluation of 2-Bromoisobutyryl Catechol Derivatives for Atom Transfer Radical Polymerization-Functionalized Polydopamine Coatings

Hsueh, Nathanael; Chai, Christina L. L., Langmuir, 2021, 37(29), 8811-8820

Production Method 15

120-14-9

93-03-8

Reaction Conditions

1.1 Reagents: Potassium carbonate Catalysts: 2402734-65-8 Solvents: Isopropanol ;  30 min, 82 °C

Reference

CNN pincer ruthenium complexes for efficient transfer hydrogenation of biomass-derived carbonyl compounds

Figliolia, Rosario; Cavigli, Paolo; Comuzzi, Clara; Del Zotto, Alessandro; Lovison, Denise; et al, Dalton Transactions, 2020, 49(2), 453-465

Production Method 16

120-14-9

93-03-8

Reaction Conditions

1.1 Reagents: Sodium borohydride Solvents: Methanol ;  -3 °C; 30 min, -3 °C
1.2 Reagents: Hydrochloric acid Solvents: Water ;  pH 7

Reference

Synthesis of analogues of salidroside

Chen, Hui; Cui, Ying; Li, Lingzhi, Di-San Junyi Daxue Xuebao, 2012, 34(11), 1057-1061

Production Method 17

120-14-9

93-03-8

Reaction Conditions

1.1 Reagents: Sodium borohydride Solvents: Methanol ;  0 °C; 30 min, 0 °C
1.2 Reagents: Water

Reference

Synthesis of resveratrol-based natural products as fungicides, sunscreens and for treatment of skin cancer

, World Intellectual Property Organization, , ,

Production Method 18

120-14-9

93-03-8

Reaction Conditions

1.1 Reagents: Sodium borohydride Solvents: Methanol ;  30 min, 0 °C
1.2 Reagents: Water

Reference

Total Synthesis of Diverse Carbogenic Complexity within the Resveratrol Class from a Common Building Block

Snyder, Scott A.; Breazzano, Steven P.; Ross, Audrey G.; Lin, Yunqing; Zografos, Alexandros L., Journal of the American Chemical Society, 2009, 131(5), 1753-1765

Production Method 19

120-14-9

93-03-8

Reaction Conditions

1.1 Reagents: Water ;  17 h, 45 °C

Reference

A mechanistic perspective on the mechanochemical method to reduce carbonyl groups with stainless steel and water

Mokhtar, Mennatullah M.; Andersen, Joel M.; Kister, Ethan A.; Hopkins, Jordan X.; Estier, Tom; et al, European Journal of Organic Chemistry, 2023, 26(23),

Production Method 20

120-14-9

93-03-8

Reaction Conditions

1.1 Reagents: Sodium borohydride Solvents: Methanol ;  overnight, rt

Reference

Synthesis 3,4-dimethoxybenzyl-2,4-dihydroxyphenyl ketone from eugenol

Matsjeh, S.; Anwar, C.; Sholikhah, E. N.; Alimuddin, A. A., International Journal of Chemical Engineering and Applications, 2015, 6(1), 61-65

Veratryl alcohol Raw materials

• Veratraldehyde
• 3,4-Dimethoxytoluene

Veratryl alcohol Preparation Products

• Veratryl alcohol (93-03-8)

• 1. An artificial photosynthetic system for photoaccumulation of two electrons on a fused dipyridophenazine (dppz)–pyridoquinolinone ligand?
  Philipp Traber,Stephan Kupfer,Stefanie Gr?fe,Isabelle Baussanne,Martine Demeunynck,Jean-Marie Mouesca,Serge Gambarelli,Vincent Artero,Murielle Chavarot-Kerlidou Chem. Sci., 2018,9, 4152-4159
• 2. An aptasensor for the detection of ampicillin in milk using a personal glucose meter
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• 3. Acetylcholinesterase amperometric detection system based on a cobalt(II) tetraphenylporphyrin-modified electrode
  Analyst, 1996,121, 1123-1126
• 4. An insight into the role of side chains in the microstructure and carrier mobility of high-performance conjugated polymers?
  Jianyao Huang,Dong Gao,Zhihui Chen,Weifeng Zhang Polym. Chem., 2021,12, 2471-2480
• 5. An integrated chip for immunofluorescence and its application to analyze lysosomal storage disorders
  Jie Shen,Ying Zhou,Tu Lu,Junya Peng,Zhixiang Lin,Yuhong Pang,Li Yu Lab Chip, 2012,12, 317-324

• Solvents and Organic Chemicals Organic Compounds Benzenoids Benzene and substituted derivatives Dimethoxybenzenes
• Solvents and Organic Chemicals Organic Compounds Benzenoids Benzene and substituted derivatives Methoxybenzenes Dimethoxybenzenes
• Solvents and Organic Chemicals Organic Compounds Alcohol/Ether

• 83459-29-4(3,4-Diethoxybenzyl alcohol)
• 22943-99-3(1,2-Benzenedimethanol,4,5-dimethoxy-)
• 147730-26-5((3-Ethoxy-4-methoxyphenyl)methanol)
• 530-56-3(Syringyl Alcohol)
• 61813-58-9(4-Ethoxy-3-methoxybenzyl alcohol)
• 4912-58-7(3-Ethoxy-4-hydroxybenzyl Alcohol)
• 122271-46-9(Benzenemethanol,3-hydroxy-4,5-dimethoxy-)
• 3840-31-1(3,4,5-Trimethoxybenzyl Alcohol)
• 4383-06-6(5-(hydroxymethyl)-2-methoxyphenol)
• 498-00-0(Vanillyl alcohol)