- Synthesis of gefitinib from methyl 3-hydroxy-4-methoxy-benzoateLi, Ming Dong; et al, Molecules, 2007, 12(3), 673-678
Cas no 912556-91-3 (N-(3-chloro-4-fluoro-phenyl)-6-(3-chloropropoxy)-7-methoxy-quinazolin-4-amine)
912556-91-3 structure
Product Name:N-(3-chloro-4-fluoro-phenyl)-6-(3-chloropropoxy)-7-methoxy-quinazolin-4-amine
CAS No:912556-91-3
MF:C18H16Cl2FN3O2
MW:396.242945671082
MDL:MFCD26383919
CID:1006173
Update Time:2024-10-26
N-(3-chloro-4-fluoro-phenyl)-6-(3-chloropropoxy)-7-methoxy-quinazolin-4-amine Chemical and Physical Properties
Names and Identifiers
-
- N-(3-Chloro-4-fluorophenyl)-6-(3-chloropropoxy)-7-methoxyquinazolin-4-amine
- 4-QUINAZOLINAMINE, N-(3-CHLORO-4-FLUOROPHENYL)-6-(3-CHLOROPROPOXY)-7-METHOXY-
- 6-(3-chloropropoxy)-N-(3-chloro-4-fluorophenyl)-7-methoxyquinazolin-4-amine
- N-(3-chloro-4-fluorophenyl)-6-(3-chloropropoxy)-7-methoxy-4-Quinazolinamine
- Gefitinib InterMediate B
- AK126834
- C18H16Cl2FN3O2
- LYHIGZLXZKJTPS-UHFFFAOYSA-N
- AMX10170
- ST2419654
- AX8248625
- Z5329
- N-(3-chloro-4-fluorophenyl)-6-(3-chloropropoxy)-7-
- 4-[(3-Chloro-4-fluorophenyl)amino]-6-(3-chloropropoxy)-7-methoxyquinazoline
- 4-Quinazolinamin
- N-(3-Chloro-4-fluorophenyl)-6-(3-chloropropoxy)-7-methoxy-4-quinazolinamine (ACI)
- N-(3-chloro-4-fluoro-phenyl)-6-(3-chloropropoxy)-7-methoxy-quinazolin-4-amine
-
- MDL： MFCD26383919
- Inchi： 1S/C18H16Cl2FN3O2/c1-25-16-9-15-12(8-17(16)26-6-2-5-19)18(23-10-22-15)24-11-3-4-14(21)13(20)7-11/h3-4,7-10H,2,5-6H2,1H3,(H,22,23,24)
- InChI Key： LYHIGZLXZKJTPS-UHFFFAOYSA-N
- SMILES： FC1C(Cl)=CC(NC2C3C(=CC(=C(C=3)OCCCCl)OC)N=CN=2)=CC=1
Computed Properties
- Hydrogen Bond Donor Count: 1
- Hydrogen Bond Acceptor Count: 6
- Heavy Atom Count: 26
- Rotatable Bond Count: 7
- Complexity: 437
- Topological Polar Surface Area: 56.3
N-(3-chloro-4-fluoro-phenyl)-6-(3-chloropropoxy)-7-methoxy-quinazolin-4-amine Security Information
- Signal Word：Warning
- Hazard Statement： H302-H315-H319-H335
- Warning Statement： P261-P305+P351+P338
- Storage Condition：Keep in dark place,Inert atmosphere,2-8°C
N-(3-chloro-4-fluoro-phenyl)-6-(3-chloropropoxy)-7-methoxy-quinazolin-4-amine Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| SHANG HAI MAI KE LIN SHENG HUA Technology Co., Ltd. | N848439-100mg |
N-(3-Chloro-4-fluorophenyl)-6-(3-chloropropoxy)-7-methoxyquinazolin-4-amine |
912556-91-3 | 97% | 100mg |
￥1,016.10 | 2022-09-01 | |
| SHANG HAI JI ZHI SHENG HUA Technology Co., Ltd. | N58330-100mg |
N-(3-Chloro-4-fluorophenyl)-6-(3-chloropropoxy)-7-methoxyquinazolin-4-amine |
912556-91-3 | 100mg |
￥956.0 | 2021-09-04 | ||
| SHANG HAI JI ZHI SHENG HUA Technology Co., Ltd. | N58330-250mg |
N-(3-Chloro-4-fluorophenyl)-6-(3-chloropropoxy)-7-methoxyquinazolin-4-amine |
912556-91-3 | 250mg |
￥1526.0 | 2021-09-04 | ||
| SHANG HAI MAI KE LIN SHENG HUA Technology Co., Ltd. | N848439-25mg |
N-(3-Chloro-4-fluorophenyl)-6-(3-chloropropoxy)-7-methoxyquinazolin-4-amine |
912556-91-3 | 97% | 25mg |
￥421.20 | 2022-09-01 | |
| SHANG HAI A LA DING SHENG HUA KE JI GU FEN Co., Ltd. | N195785-100mg |
N-(3-chloro-4-fluoro-phenyl)-6-(3-chloropropoxy)-7-methoxy-quinazolin-4-amine |
912556-91-3 | 97% | 100mg |
￥575.90 | 2023-09-01 | |
| SHANG HAI A LA DING SHENG HUA KE JI GU FEN Co., Ltd. | N195785-25mg |
N-(3-chloro-4-fluoro-phenyl)-6-(3-chloropropoxy)-7-methoxy-quinazolin-4-amine |
912556-91-3 | 97% | 25mg |
￥241.90 | 2023-09-01 | |
| SHANG HAI XIAN DING Biotechnology Co., Ltd. | B-LM231-100mg |
N-(3-chloro-4-fluoro-phenyl)-6-(3-chloropropoxy)-7-methoxy-quinazolin-4-amine |
912556-91-3 | 97% | 100mg |
533CNY | 2021-05-08 | |
| SHANG HAI XIAN DING Biotechnology Co., Ltd. | B-LM231-250mg |
N-(3-chloro-4-fluoro-phenyl)-6-(3-chloropropoxy)-7-methoxy-quinazolin-4-amine |
912556-91-3 | 97% | 250mg |
1098CNY | 2021-05-08 | |
| Chemenu | CM118511-1g |
4-[(3-Chloro-4-fluorophenyl)amino]-6-(3-chloropropoxy)-7-methoxyquinazoline |
912556-91-3 | 97% | 1g |
$468 | 2021-08-06 | |
| SHANG HAI BI DE YI YAO KE JI GU FEN Co., Ltd. | BD248625-100mg |
N-(3-Chloro-4-fluorophenyl)-6-(3-chloropropoxy)-7-methoxyquinazolin-4-amine |
912556-91-3 | 97% | 100mg |
￥460.0 | 2024-04-17 |
N-(3-chloro-4-fluoro-phenyl)-6-(3-chloropropoxy)-7-methoxy-quinazolin-4-amine Production Method
Production Method 1
Reaction Conditions
1.1 Solvents: Isopropanol ; rt; rt → reflux; 3 h, reflux; overnight, cooled
Reference
Production Method 2
Reaction Conditions
1.1 Reagents: Acetic acid Solvents: Toluene ; 30 min, rt → 95 °C
1.2 Solvents: Acetic acid ; 3 h, 130 °C; 130 °C → rt
1.3 Reagents: Ammonia Solvents: Water ; pH 9, cooled
1.2 Solvents: Acetic acid ; 3 h, 130 °C; 130 °C → rt
1.3 Reagents: Ammonia Solvents: Water ; pH 9, cooled
Reference
- Study on synthetic method of antineoplastic gefitinibSun, Jian; et al, Huaxue Yanjiu Yu Yingyong, 2013, 25(8), 1180-1184
Production Method 3
Reaction Conditions
1.1 Solvents: Acetic acid ; rt → 130 °C; 30 min, 130 °C; 130 °C → 25 °C
1.2 Reagents: Water ; cooled
1.3 Reagents: Ammonia Solvents: Water ; 30 min, pH 9 - 10, cooled
1.2 Reagents: Water ; cooled
1.3 Reagents: Ammonia Solvents: Water ; 30 min, pH 9 - 10, cooled
Reference
- Quinazoline-1-deoxynojirimycin hybrids as high active dual inhibitors of EGFR and α-glucosidaseZhang, Yaling; et al, Bioorganic & Medicinal Chemistry Letters, 2017, 27(18), 4309-4313
Production Method 4
Reaction Conditions
1.1 Solvents: Isopropanol ; 3 h, reflux; reflux → rt
Reference
- Synthesis of 4-(3-chloro-4-fluorophenylamino)-7-methoxy-6-[3-(4-morpholinyl)propoxy]quinazoline (ZD1839)Yuan, Li; et al, Zhongguo Yaowu Huaxue Zazhi, 2005, 15(1), 39-41
Production Method 5
Reaction Conditions
1.1 Reagents: Thionyl chloride Solvents: Chloroform ; 7 - 8 h, rt → reflux
1.2 Solvents: Isopropanol ; 10 °C; 2 h, 10 °C → reflux
1.2 Solvents: Isopropanol ; 10 °C; 2 h, 10 °C → reflux
Reference
- A Convenient and Easy Purification Approach to High-Yield Synthesis of Gefitinib as an Anticancer Agent from IsovanilineChandrasekhar, M.; et al, Pharmaceutical Chemistry Journal, 2014, 48(8), 520-524
Production Method 6
Reaction Conditions
1.1 Reagents: Thionyl chloride Catalysts: Dimethylformamide Solvents: Dichloromethane ; 0.5 h, rt; rt → reflux; 12 h, reflux
2.1 Solvents: Isopropanol
2.1 Solvents: Isopropanol
Reference
- Study on synthesis process of gefitinibXu, Jian-kang; et al, Huaxi Yaoxue Zazhi, 2012, 27(4), 362-364
Production Method 7
Reaction Conditions
1.1 Reagents: Phosphorus oxychloride ; 90 °C
2.1 Reagents: Thionyl chloride Solvents: Dimethylformamide ; reflux
3.1 Reagents: Triethylamine Solvents: Isopropanol ; rt
2.1 Reagents: Thionyl chloride Solvents: Dimethylformamide ; reflux
3.1 Reagents: Triethylamine Solvents: Isopropanol ; rt
Reference
- Novel EGFR inhibitors prepared by combination of dithiocarbamic acid esters and 4-anilinoquinazolinesLi, Ri-Dong; et al, Bioorganic & Medicinal Chemistry Letters, 2011, 21(12), 3637-3640
Production Method 8
Reaction Conditions
1.1 Reagents: Thionyl chloride Solvents: Dimethylformamide ; reflux
2.1 Reagents: Triethylamine Solvents: Isopropanol ; rt
2.1 Reagents: Triethylamine Solvents: Isopropanol ; rt
Reference
- Novel EGFR inhibitors prepared by combination of dithiocarbamic acid esters and 4-anilinoquinazolinesLi, Ri-Dong; et al, Bioorganic & Medicinal Chemistry Letters, 2011, 21(12), 3637-3640
Production Method 9
Reaction Conditions
1.1 Reagents: Thionyl chloride Solvents: Dimethylformamide ; rt; rt → reflux; 4 h, reflux
2.1 Solvents: Isopropanol ; rt; rt → reflux; 3 h, reflux; overnight, cooled
2.1 Solvents: Isopropanol ; rt; rt → reflux; 3 h, reflux; overnight, cooled
Reference
- Synthesis of gefitinib from methyl 3-hydroxy-4-methoxy-benzoateLi, Ming Dong; et al, Molecules, 2007, 12(3), 673-678
Production Method 10
Reaction Conditions
1.1 Reagents: Sulfuric acid , Nitric acid Solvents: Acetic acid , Water ; cooled; 2 - 4 h, 35 - 40 °C
1.2 Reagents: Water
2.1 Reagents: Sodium dithionite Solvents: Methanol , Water ; rt → 45 °C; 20 min, 40 - 45 °C; 45 °C → 60 °C; 50 - 60 °C
2.2 Reagents: Hydrochloric acid Solvents: Water ; 0.5 h, 50 - 60 °C; 2 h, 50 - 60 °C; 60 °C → rt
2.3 Reagents: Sodium hydroxide Solvents: Water ; pH 10
3.1 Reagents: Acetic acid Solvents: Toluene ; 30 min, rt → 95 °C
3.2 Solvents: Acetic acid ; 3 h, 130 °C; 130 °C → rt
3.3 Reagents: Ammonia Solvents: Water ; pH 9, cooled
1.2 Reagents: Water
2.1 Reagents: Sodium dithionite Solvents: Methanol , Water ; rt → 45 °C; 20 min, 40 - 45 °C; 45 °C → 60 °C; 50 - 60 °C
2.2 Reagents: Hydrochloric acid Solvents: Water ; 0.5 h, 50 - 60 °C; 2 h, 50 - 60 °C; 60 °C → rt
2.3 Reagents: Sodium hydroxide Solvents: Water ; pH 10
3.1 Reagents: Acetic acid Solvents: Toluene ; 30 min, rt → 95 °C
3.2 Solvents: Acetic acid ; 3 h, 130 °C; 130 °C → rt
3.3 Reagents: Ammonia Solvents: Water ; pH 9, cooled
Reference
- Study on synthetic method of antineoplastic gefitinibSun, Jian; et al, Huaxue Yanjiu Yu Yingyong, 2013, 25(8), 1180-1184
Production Method 11
Reaction Conditions
1.1 Reagents: Tripotassium phosphate Solvents: N-Methyl-2-pyrrolidone ; 20 h, 10 °C
Reference
- Manufacturable Process of a Novel EGFR Inhibitor (Larotinib) for the Treatment of ESCCZhang, Weihong ; et al, Organic Process Research & Development, 2022, 26(5), 1470-1485
Production Method 12
Reaction Conditions
1.1 Solvents: Isopropanol
Reference
- Study on synthesis process of gefitinibXu, Jian-kang; et al, Huaxi Yaoxue Zazhi, 2012, 27(4), 362-364
Production Method 13
Reaction Conditions
1.1 Catalysts: Acetic acid Solvents: Toluene ; rt → 110 °C; 4 h, 105 - 110 °C
1.2 Catalysts: Acetic acid ; rt → 130 °C; 4 h, 125 - 130 °C; 130 °C → rt
1.3 Reagents: Ammonia Solvents: Water ; pH 9, 0 °C
1.2 Catalysts: Acetic acid ; rt → 130 °C; 4 h, 125 - 130 °C; 130 °C → rt
1.3 Reagents: Ammonia Solvents: Water ; pH 9, 0 °C
Reference
- Synthesis and biological evaluation of selenogefitinib for reducing bleomycin-induced pulmonary fibrosisBai, Yue; et al, Bioorganic & Medicinal Chemistry Letters, 2021, 48,
Production Method 14
Reaction Conditions
1.1 Solvents: Acetic acid ; 3 h, reflux
1.2 Reagents: Ammonia Solvents: Water ; pH 9, cooled
1.2 Reagents: Ammonia Solvents: Water ; pH 9, cooled
Reference
- Synthesis of gefitinibLv, Tong-jie; et al, Guangzhou Huagong, 2010, 38(12), 154-156
Production Method 15
Reaction Conditions
1.1 Reagents: Zinc , Ammonium chloride Solvents: Ethanol , Water ; 30 min, rt → 60 °C
2.1 Catalysts: Acetic acid Solvents: Toluene ; rt → 110 °C; 4 h, 105 - 110 °C
2.2 Catalysts: Acetic acid ; rt → 130 °C; 4 h, 125 - 130 °C; 130 °C → rt
2.3 Reagents: Ammonia Solvents: Water ; pH 9, 0 °C
2.1 Catalysts: Acetic acid Solvents: Toluene ; rt → 110 °C; 4 h, 105 - 110 °C
2.2 Catalysts: Acetic acid ; rt → 130 °C; 4 h, 125 - 130 °C; 130 °C → rt
2.3 Reagents: Ammonia Solvents: Water ; pH 9, 0 °C
Reference
- Synthesis and biological evaluation of selenogefitinib for reducing bleomycin-induced pulmonary fibrosisBai, Yue; et al, Bioorganic & Medicinal Chemistry Letters, 2021, 48,
Production Method 16
Reaction Conditions
1.1 Reagents: Sodium dithionite Solvents: Methanol , Water ; rt → 45 °C; 20 min, 40 - 45 °C; 45 °C → 60 °C; 50 - 60 °C
1.2 Reagents: Hydrochloric acid Solvents: Water ; 0.5 h, 50 - 60 °C; 2 h, 50 - 60 °C; 60 °C → rt
1.3 Reagents: Sodium hydroxide Solvents: Water ; pH 10
2.1 Reagents: Acetic acid Solvents: Toluene ; 30 min, rt → 95 °C
2.2 Solvents: Acetic acid ; 3 h, 130 °C; 130 °C → rt
2.3 Reagents: Ammonia Solvents: Water ; pH 9, cooled
1.2 Reagents: Hydrochloric acid Solvents: Water ; 0.5 h, 50 - 60 °C; 2 h, 50 - 60 °C; 60 °C → rt
1.3 Reagents: Sodium hydroxide Solvents: Water ; pH 10
2.1 Reagents: Acetic acid Solvents: Toluene ; 30 min, rt → 95 °C
2.2 Solvents: Acetic acid ; 3 h, 130 °C; 130 °C → rt
2.3 Reagents: Ammonia Solvents: Water ; pH 9, cooled
Reference
- Study on synthetic method of antineoplastic gefitinibSun, Jian; et al, Huaxue Yanjiu Yu Yingyong, 2013, 25(8), 1180-1184
Production Method 17
Reaction Conditions
1.1 Solvents: Acetic acid , Toluene , Dimethylacetamide ; rt → 40 °C; 15 min, 35 - 40 °C; 35 °C → 25 °C
1.2 Reagents: Sodium hydroxide Solvents: Water ; pH 13
2.1 Solvents: Acetic acid ; rt → 130 °C; 30 min, 130 °C; 130 °C → 25 °C
2.2 Reagents: Water ; cooled
2.3 Reagents: Ammonia Solvents: Water ; 30 min, pH 9 - 10, cooled
1.2 Reagents: Sodium hydroxide Solvents: Water ; pH 13
2.1 Solvents: Acetic acid ; rt → 130 °C; 30 min, 130 °C; 130 °C → 25 °C
2.2 Reagents: Water ; cooled
2.3 Reagents: Ammonia Solvents: Water ; 30 min, pH 9 - 10, cooled
Reference
- Quinazoline-1-deoxynojirimycin hybrids as high active dual inhibitors of EGFR and α-glucosidaseZhang, Yaling; et al, Bioorganic & Medicinal Chemistry Letters, 2017, 27(18), 4309-4313
Production Method 18
Reaction Conditions
1.1 Reagents: Formamide ; rt → reflux; 6 h, reflux
1.2 Reagents: Water
2.1 Reagents: Thionyl chloride Solvents: Chloroform ; 7 - 8 h, rt → reflux
2.2 Solvents: Isopropanol ; 10 °C; 2 h, 10 °C → reflux
1.2 Reagents: Water
2.1 Reagents: Thionyl chloride Solvents: Chloroform ; 7 - 8 h, rt → reflux
2.2 Solvents: Isopropanol ; 10 °C; 2 h, 10 °C → reflux
Reference
- A Convenient and Easy Purification Approach to High-Yield Synthesis of Gefitinib as an Anticancer Agent from IsovanilineChandrasekhar, M.; et al, Pharmaceutical Chemistry Journal, 2014, 48(8), 520-524
Production Method 19
Reaction Conditions
1.1 Reagents: Sodium hydroxide Solvents: Methanol , Water ; 25 °C; 4 h, 25 °C
1.2 Reagents: Hydrochloric acid Solvents: Water ; 10 min, 25 °C
2.1 Reagents: Tripotassium phosphate Solvents: N-Methyl-2-pyrrolidone ; 20 h, 10 °C
1.2 Reagents: Hydrochloric acid Solvents: Water ; 10 min, 25 °C
2.1 Reagents: Tripotassium phosphate Solvents: N-Methyl-2-pyrrolidone ; 20 h, 10 °C
Reference
- Manufacturable Process of a Novel EGFR Inhibitor (Larotinib) for the Treatment of ESCCZhang, Weihong ; et al, Organic Process Research & Development, 2022, 26(5), 1470-1485
Production Method 20
Reaction Conditions
1.1 Reagents: Acetic acid Solvents: Toluene ; 3 h, reflux
2.1 Solvents: Acetic acid ; 3 h, reflux
2.2 Reagents: Ammonia Solvents: Water ; pH 9, cooled
2.1 Solvents: Acetic acid ; 3 h, reflux
2.2 Reagents: Ammonia Solvents: Water ; pH 9, cooled
Reference
- Synthesis of gefitinibLv, Tong-jie; et al, Guangzhou Huagong, 2010, 38(12), 154-156
Production Method 21
Reaction Conditions
1.1 Reagents: Triethylamine , Phosphorus oxychloride Solvents: Toluene ; reflux
2.1 Solvents: Isopropanol ; reflux
2.1 Solvents: Isopropanol ; reflux
Reference
- Four-membered heterocycles-containing 4-anilino-quinazoline derivatives as epidermal growth factor receptor (EGFR) kinase inhibitorsZhao, Feng; et al, Bioorganic & Medicinal Chemistry Letters, 2013, 23(19), 5385-5388
Production Method 22
Reaction Conditions
1.1 Reagents: Sulfuric acid , Nitric acid Solvents: Acetic acid , Water ; 2 h, rt
2.1 Reagents: Zinc , Ammonium chloride Solvents: Ethanol , Water ; 30 min, rt → 60 °C
3.1 Catalysts: Acetic acid Solvents: Toluene ; rt → 110 °C; 4 h, 105 - 110 °C
3.2 Catalysts: Acetic acid ; rt → 130 °C; 4 h, 125 - 130 °C; 130 °C → rt
3.3 Reagents: Ammonia Solvents: Water ; pH 9, 0 °C
2.1 Reagents: Zinc , Ammonium chloride Solvents: Ethanol , Water ; 30 min, rt → 60 °C
3.1 Catalysts: Acetic acid Solvents: Toluene ; rt → 110 °C; 4 h, 105 - 110 °C
3.2 Catalysts: Acetic acid ; rt → 130 °C; 4 h, 125 - 130 °C; 130 °C → rt
3.3 Reagents: Ammonia Solvents: Water ; pH 9, 0 °C
Reference
- Synthesis and biological evaluation of selenogefitinib for reducing bleomycin-induced pulmonary fibrosisBai, Yue; et al, Bioorganic & Medicinal Chemistry Letters, 2021, 48,
N-(3-chloro-4-fluoro-phenyl)-6-(3-chloropropoxy)-7-methoxy-quinazolin-4-amine Raw materials
- (dimethoxymethyl)dimethylamine
- 4-((3-Chloro-4-fluorophenyl)amino)-7-methoxyquinazolin-6-yl acetate hydrochloride
- 2-Amino-5-(3-chloropropoxy)-4-methoxybenzoic acid methylester
- 4(3H)-Quinazolinone, 6-(3-hydroxypropoxy)-7-methoxy-
- 5-(3-chloropropoxy)-4-methoxy-2-nitro Benzonitrile
- 3-Chloro-4-fluoroaniline
- 6-(3-chloropropoxy)-7-methoxyquinazolin-4(3H)-one
- Benzonitrile, 3-(3-chloropropoxy)-4-methoxy-
- Formamide
- FAAH-IN-2
- 4-chloro-6-(3-chloropropoxy)-7-methoxyquinazoline
- Benzonitrile, 2-amino-5-(3-chloropropoxy)-4-methoxy-
- Methanimidamide, N'-[4-(3-chloropropoxy)-2-cyano-5-methoxyphenyl]-N,N-dimethyl-
- Quinazoline, 4-chloro-6-(3-chloropropoxy)-7-methoxy-, hydrochloride (1:1)
- Methanimidamide, N'-(3-chloro-4-fluorophenyl)-N,N-dimethyl-
- Benzamide, 2-amino-5-(3-chloropropoxy)-4-methoxy-
N-(3-chloro-4-fluoro-phenyl)-6-(3-chloropropoxy)-7-methoxy-quinazolin-4-amine Preparation Products
N-(3-chloro-4-fluoro-phenyl)-6-(3-chloropropoxy)-7-methoxy-quinazolin-4-amine Related Literature
-
Michael Kappl,Paul M. Young,Daniela Traini,Sanyog Jain RSC Adv., 2016,6, 25789-25798
-
Ravi Kumar Yadav,R. Govindaraj Phys. Chem. Chem. Phys., 2020,22, 26876-26886
-
Yang Xu,Min Wang,Donghui Wei,Rongqiang Tian,Zheng Duan,Fran?ois Mathey Dalton Trans., 2019,48, 5523-5526
-
Sandip Gangadhar Balwe,Yeon Tae Jeong Org. Biomol. Chem., 2018,16, 1287-1296
-
Kanjun Sun,Fengting Hua,Shuzhen Cui,Yanrong Zhu,Hui Peng,Guofu Ma RSC Adv., 2021,11, 37631-37642
Related Categories
- Solvents and Organic Chemicals Organic Compounds Organoheterocyclic compounds Diazanaphthalenes Quinazolines
- Solvents and Organic Chemicals Organic Compounds Organoheterocyclic compounds Diazanaphthalenes Benzodiazines Quinazolines
- Solvents and Organic Chemicals Organic Compounds Amines/Sulfonamides
912556-91-3 (N-(3-chloro-4-fluoro-phenyl)-6-(3-chloropropoxy)-7-methoxy-quinazolin-4-amine) Related Products
- 184475-70-5(4-((3-Chloro-4-fluorophenyl)amino)-7-methoxyquinazolin-6-yl acetate hydrochloride)
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- 295330-62-0(6-(Benzyloxy)-4-(3-chloro-4-fluoroanilino)quinazolin-7(1H)-one)
- 913819-12-2(N-(3-Chloro-4-fluorophenyl)-7-methoxy-6-(phenylmethoxy)-4-quinazolinamine)
- 153437-03-7(4-Quinazolinamine, N-(3-chloro-4-fluorophenyl)-6,7-dimethoxy-,monohydrochloride)
- 847949-56-8(3-DesMorpholinyl-3-hydroxyethylaMino Gefitinib)
- 402855-01-0(N4-(3-Chloro-4-fluorophenyl)-7-(2-methoxyethoxy)-quinazoline-4,6-diamine)
- 612501-52-7(4-((3-Chloro-2-fluorophenyl)amino)-7-methoxyquinazolin-6-ol)
- 184475-71-6(FAAH-IN-2)
- 655247-75-9(4-Quinazolinamine,6-(3-aminopropoxy)-N-(3-chloro-4-fluorophenyl)-7-methoxy-)
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