Production Method 1

171018-95-4

89496-02-6

Reaction Conditions

1.1 Reagents: Sodium hydroxide Solvents: Ethanol ,  Water ;  8 h, reflux
1.2 Reagents: Hydrochloric acid Solvents: Water ;  pH 2 - 3, rt

Reference

The Enantiospecific, Stereospecific Total Synthesis of the Ring-A Oxygenated Sarpagine Indole Alkaloids (+)-Majvinine, (+)-10-Methoxyaffinisine, and (+)-Na-Methylsarpagine, as Well as the Total Synthesis of the Alstonia Bisindole Alkaloid Macralstonidine

Zhao, Shuo; Liao, Xuebin; Wang, Tao; Flippen-Anderson, Judith; Cook, James M., Journal of Organic Chemistry, 2003, 68(16), 6279-6295

Production Method 2

171018-95-4

89496-02-6

Reaction Conditions

1.1 Reagents: Sodium hydroxide Solvents: Ethanol ,  Water

Reference

Enantiospecific synthesis of 5-methoxy-D(+)- or L(-)Tryptophan

Zhang, Puwen; Cook, James M., Synthetic Communications, 1995, 25(23), 3883-900

Production Method 3

28052-84-8

89496-02-6

Reaction Conditions

1.1 Reagents: Ammonia borane Catalysts: L-Amino acid oxidase Solvents: Water ;  20 h, pH 8, 30 °C
1.2 Reagents: Perchloric acid Solvents: Water

Reference

Deracemization and Stereoinversion to Aromatic D-Amino Acid Derivatives with Ancestral L-Amino Acid Oxidase

Nakano, Shogo ; Minamino, Yuki; Hasebe, Fumihito; Ito, Sohei, ACS Catalysis, 2019, 9(11), 10152-10158

Production Method 4

89496-02-6

Reaction Conditions

1.1 Reagents: Hydrochloric acid Solvents: Water

Reference

Synthesis, resolution and characterization of ring substituted phenylalanines and tryptophans

Porter, John; Dykert, John; Rivier, Jean, International Journal of Peptide & Protein Research, 1987, 30(1), 13-21

(R)-2-Amino-3-(5-methoxy-1H-indol-3-yl)propanoic acid Raw materials

• D-Tryptophan, 5-methoxy-1-(phenylsulfonyl)-, ethyl ester, monohydrochloride (9CI)
• 5-Methoxy-DL-tryptophan

(R)-2-Amino-3-(5-methoxy-1H-indol-3-yl)propanoic acid Preparation Products

• (R)-2-Amino-3-(5-methoxy-1H-indol-3-yl)propanoic acid (89496-02-6)

• 1. An all-solid-state asymmetric device based on a polyaniline hydrogel for a high energy flexible supercapacitor?
  Hamid Heydari,Mohammad B. Gholivand New J. Chem., 2017,41, 237-244
• 2. An integrated cathode and solid electrolyte via in situ polymerization with significantly reduced interface resistance?
  Jialiang Yuan,Ran Dong,Yuan Li,Yang Liu,Zhuo Zheng,Yuxia Liu,Yan Sun,Benhe Zhong,Zhenguo Wu,Xiaodong Guo Chem. Commun., 2021,57, 13004-13007
• 3. An algal process treatment combined with the Fenton reaction for high concentrations of amoxicillin and cefradine
  Haitao Li,Yu Pan,Zhizhi Wang,Shan Chen,Ruixin Guo,Jianqiu Chen RSC Adv., 2015,5, 100775-100782
• 4. An integrated microfluidic 3D tumor system for parallel and high-throughput chemotherapy evaluation?
  Dan Liu,Rui Hu,Zhongchao Huang,Meilin Sun,Kai Han Analyst, 2020,145, 6447-6455
• 5. An aptasensor for the detection of ampicillin in milk using a personal glucose meter
  Xixi Li,Nanwei Zhu,Ruohan Li,Qinpu Zhang Anal. Methods, 2020,12, 3376-3381

• Solvents and Organic Chemicals Organic Compounds Organoheterocyclic compounds Indoles and derivatives Serotonins
• Solvents and Organic Chemicals Organic Compounds Organoheterocyclic compounds Indoles and derivatives Tryptamines and derivatives Serotonins

• 25197-96-0((S)\u200b-\u200b2-\u200bAmino-\u200b3-\u200b(5-\u200bmethoxy-\u200b1H-\u200bindol-\u200b3-\u200byl)\u200bpropanoic Acid)
• 145224-90-4(L-Tryptophan,5-hydroxy-, dihydrate (9CI))
• 808145-87-1(D-Tryptophan,7-methoxy-)
• 4350-09-8(5-Hydroxy L-Tryptophan)
• 107447-04-1((S)-Methyl 2-aMino-3-(6-Methoxy-1H-indol-3-yl)propanoate)
• 56-69-9(5-Hydroxy Tryptophan)
• 16730-11-3(6-Methoxy-L-tryptophan)
• 1956-25-8(5-Benzyloxy-DL-tryptophan)
• 114-03-4(5-Hydroxy-D-tryptophan)
• 314062-44-7(5-Hydroxy-L-Tryptophan hydrate)