Cas no 16730-11-3 (6-Methoxy-L-tryptophan)

6-Methoxy-L-tryptophan is a modified amino acid derivative of L-tryptophan, featuring a methoxy group at the 6-position of the indole ring. This structural modification enhances its stability and potential biological activity, making it a valuable intermediate in pharmaceutical and biochemical research. It is particularly relevant in studies involving serotonin biosynthesis and neurotransmitter regulation due to its role as a precursor in metabolic pathways. The compound’s high purity and well-defined structure ensure reproducibility in experimental applications. Its utility extends to enzymatic studies and the synthesis of specialized peptides, offering researchers a precise tool for probing biochemical mechanisms.
6-Methoxy-L-tryptophan structure
6-Methoxy-L-tryptophan structure
Product Name:6-Methoxy-L-tryptophan
CAS No:16730-11-3
MF:C12H14N2O3
MW:234.251163005829
MDL:MFCD06797689
CID:835892
PubChem ID:15408556
Update Time:2025-10-22

6-Methoxy-L-tryptophan Chemical and Physical Properties

Names and Identifiers

    • (S)-2-Amino-3-(6-methoxy-1H-indol-3-yl)propanoic acid
    • (2S)-2-amino-3-(6-methoxy-1H-indol-3-yl)propanoic acid
    • (R)-2-acetaMido-3-(6-Methoxy-1H-indol-3-yl)propanoic acid
    • 6-Methoxy-L-tryptophan
    • L-Tryptophan, 6-methoxy-
    • L-6-Methoxytryptophan
    • Tryptophan, 6-methoxy-
    • (S)-2-amino-3-(6-methoxy-1H-indol-3-yl)propanoicacid
    • 8531AA
    • AX8237659
    • DTXSID90572504
    • DB-328087
    • AKOS016843458
    • L-6-Methoxytryptophan (H-L-Trp(6-OMe)-OH)
    • CS-M0886
    • CS-13723
    • MFCD06797689
    • 16730-11-3
    • SCHEMBL1460679
    • MDL: MFCD06797689
    • Inchi: 1S/C12H14N2O3/c1-17-8-2-3-9-7(4-10(13)12(15)16)6-14-11(9)5-8/h2-3,5-6,10,14H,4,13H2,1H3,(H,15,16)/t10-/m0/s1
    • InChI Key: ASMBUJRMSWTSLE-JTQLQIEISA-N
    • SMILES: O(C)C1C=CC2=C(C=1)NC=C2C[C@@H](C(=O)O)N

Computed Properties

  • Exact Mass: 234.10044231g/mol
  • Monoisotopic Mass: 234.10044231g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 3
  • Hydrogen Bond Acceptor Count: 4
  • Heavy Atom Count: 17
  • Rotatable Bond Count: 4
  • Complexity: 285
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 1
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • XLogP3: -0.9
  • Topological Polar Surface Area: 88.3

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6-Methoxy-L-tryptophan Suppliers

Amadis Chemical Company Limited
Gold Member
Audited Supplier Audited Supplier
(CAS:16730-11-3)6-Methoxy-L-tryptophan
Order Number:A854462
Stock Status:in Stock
Quantity:1g/5g
Purity:99%
Pricing Information Last Updated:Friday, 30 August 2024 07:50
Price ($):327.0/1287.0

Additional information on 6-Methoxy-L-tryptophan

Introduction to 6-Methoxy-L-tryptophan (CAS No. 16730-11-3)

6-Methoxy-L-tryptophan, with the chemical identifier CAS No. 16730-11-3, is a significant compound in the field of pharmaceutical chemistry and biochemistry. This amino acid derivative has garnered considerable attention due to its unique structural properties and its potential applications in various biological and medical research areas. The methoxy group at the 6-position of the tryptophan molecule introduces distinct pharmacological characteristics, making it a valuable candidate for further investigation.

The synthesis and characterization of 6-Methoxy-L-tryptophan involve rigorous methodologies to ensure high purity and efficacy. Advanced spectroscopic techniques such as nuclear magnetic resonance (NMR) spectroscopy, mass spectrometry (MS), and high-performance liquid chromatography (HPLC) are employed to confirm the structural integrity of the compound. These analytical methods provide detailed insights into the molecular structure, helping researchers understand its interactions with biological targets.

In recent years, 6-Methoxy-L-tryptophan has been explored for its potential role in modulating neurotransmitter systems. Tryptophan is a precursor to serotonin, a neurotransmitter that plays a crucial role in mood regulation, sleep, and appetite control. The methoxy substitution in 6-Methoxy-L-tryptophan may alter its metabolic pathways and bioavailability, offering new avenues for therapeutic intervention. Preliminary studies suggest that this compound may have neuroprotective properties, making it a promising candidate for treating neurological disorders such as depression and anxiety.

Moreover, 6-Methoxy-L-tryptophan has shown promise in immunomodulatory research. The compound's ability to interact with various cellular receptors and enzymes may help in developing novel immunotherapies. Research indicates that it can influence immune cell function by modulating signaling pathways involved in inflammation and immune response. This makes it a potential candidate for applications in autoimmune diseases and cancer immunotherapy.

The pharmacokinetic profile of 6-Methoxy-L-tryptophan is another area of active investigation. Understanding how the body processes this compound is essential for optimizing its therapeutic use. Studies have begun to explore its absorption, distribution, metabolism, and excretion (ADME) properties. These studies are critical for determining appropriate dosing regimens and identifying potential side effects.

Recent advancements in computational chemistry have also contributed to the study of 6-Methoxy-L-tryptophan. Molecular modeling techniques allow researchers to predict how this compound interacts with biological targets at the atomic level. This approach helps in designing derivatives with enhanced efficacy and reduced toxicity. By leveraging computational tools, scientists can accelerate the drug discovery process and identify new therapeutic applications.

The role of 6-Methoxy-L-tryptophan in metabolic health is another emerging area of interest. Research suggests that this compound may influence metabolic pathways related to energy homeostasis and lipid metabolism. By modulating these pathways, 6-Methoxy-L-tryptophan could potentially be used in managing metabolic disorders such as obesity and type 2 diabetes.

In conclusion, 6-Methoxy-L-tryptophan (CAS No. 16730-11-3) is a versatile compound with significant potential in pharmaceutical research. Its unique structural features and biological activities make it a valuable tool for investigating neurological, immunological, and metabolic disorders. As research continues to uncover new applications for this compound, it is likely to play an increasingly important role in drug development and therapeutic innovation.

Recommended suppliers
Amadis Chemical Company Limited
(CAS:16730-11-3)6-Methoxy-L-tryptophan
A854462
Purity:99%/99%
Quantity:1g/5g
Price ($):327.0/1287.0
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