Production Method 1

33332-25-1

88625-24-5

Reaction Conditions

1.1 Reagents: Diisobutylaluminum hydride Solvents: Tetrahydrofuran ;  -78 °C; 2 h, -78 °C
1.2 Reagents: Hydrochloric acid Solvents: Water ;  pH 3

Reference

Benzoxaborole Antimalarial Agents. Part 4. Discovery of Potent 6-(2-(Alkoxycarbonyl)pyrazinyl-5-oxy)-1,3-dihydro-1-hydroxy-2,1-benzoxaboroles

Zhang, Yong-Kang; Plattner, Jacob J.; Easom, Eric E.; Jacobs, Robert T.; Guo, Denghui; et al, Journal of Medicinal Chemistry, 2015, 58(13), 5344-5354

Production Method 2

33332-25-1

88625-24-5

Reaction Conditions

1.1 Reagents: Sodium borohydride Solvents: Methanol
1.2 Reagents: Dess-Martin periodinane Solvents: Dichloromethane

Reference

Discovery of Potent Antivirals against Amantadine-Resistant Influenza A Viruses by Targeting the M2-S31N Proton Channel

Li, Fang; Ma, Chunlong; Hu, Yanmei; Wang, Yuanxiang; Wang, Jun, ACS Infectious Diseases, 2016, 2(10), 726-733

5-Chloropyrazine-2-carbaldehyde Raw materials

• Methyl 5-chloropyrazine-2-carboxylate

5-Chloropyrazine-2-carbaldehyde Preparation Products

• 5-Chloropyrazine-2-carbaldehyde (88625-24-5)

• 1. An automatic determination of thoria in thoria-urania mixtures
  Analyst, 1966,91, 208-210
• 2. An approach to 7-aza-1-phosphanorbornane complexes: strain promoted rearrangement of 1-iminylphosphirane complexes and cycloaddition with olefins?
  Yang Xu,Min Wang,Donghui Wei,Rongqiang Tian,Zheng Duan,Fran?ois Mathey Dalton Trans., 2019,48, 5523-5526
• 3. An atomic scale study of defects in Co2FeAl
  Ravi Kumar Yadav,R. Govindaraj Phys. Chem. Chem. Phys., 2020,22, 26876-26886
• 4. An antioxidant self-healing hydrogel for 3D cell cultures?
  Lei Yang,Yuan Zeng,Haibo Wu,Chunwu Zhou,Lei Tao J. Mater. Chem. B, 2020,8, 1383-1388
• 5. An amide probe as a selective Al3+ and Fe3+ sensor inside the HeLa and a549 cell lines: Pictet–Spengler reaction for the rapid detection of tryptophan amino acid?
  Bidyut Kumar Kundu,Rinky Singh,Ritudhwaj Tiwari,Debasis Nayak New J. Chem., 2019,43, 4867-4877

• Solvents and Organic Chemicals Organic Compounds Organic oxygen compounds Organooxygen compounds Carbonyl compounds Aldehydes

• 59303-10-5(2-Chloro-5-methylpyrazine)
• 160252-31-3(1-(5-chloropyrazin-2-yl)ethan-1-one)
• 1357172-39-4(3,6-Dichloropyrazine-2-carbaldehyde)
• 121246-96-6(3-Chloropyrazine-2-carbaldehyde)
• 136866-27-8(3,5-Dichloropyrazine-2-carbaldehyde)
• 88625-23-4(5-chloropyrazine-2-carbonyl chloride)
• 1384678-57-2(3-Chloro-6-methylpyrazine-2-carbaldehyde)
• 36070-80-1(5-Chloropyrazine-2-carboxylic acid)
• 1197235-63-4(3-Chloro-5-methylpyrazine-2-carbaldehyde)
• 874114-34-8(6-Chloropyrazine-2-carbaldehyde)