Cas no 885520-59-2 (6-Bromo-4-fluoro-1H-indole)

6-Bromo-4-fluoro-1H-indole is a halogenated indole derivative widely utilized as a key intermediate in pharmaceutical and agrochemical synthesis. Its bromo and fluoro substituents enhance reactivity, enabling selective functionalization in cross-coupling reactions and heterocyclic modifications. The compound’s rigid indole scaffold offers structural versatility for designing bioactive molecules, particularly in kinase inhibitors and CNS-targeting compounds. High purity grades ensure consistent performance in research and industrial applications. Its stability under standard conditions and compatibility with common organic solvents further facilitate handling in multistep synthetic routes. This compound is particularly valued for its role in developing novel therapeutic agents and advanced material science applications.

6-Bromo-4-fluoro-1H-indole structure

Product Name:6-Bromo-4-fluoro-1H-indole

CAS No:885520-59-2

MF:C₈H₅BrFN

MW:214.03440451622

MDL:MFCD07781550

CID:840692

PubChem ID:24728169

Update Time:2025-06-07

6-Bromo-4-fluoro-1H-indole Chemical and Physical Properties

Names and Identifiers

- 6-Bromo-4-fluoro-1H-indole
- 6-BROMO-4-FLUORO INDOLE
- 4-Fluoro-6-bromoindole
- 6-Bromo-4-fluoroindole
- AK119716
- 4-Fluoro-6-bromo-indole
- VTODDAKQRGKCGF-UHFFFAOYSA-N
- 4351AC
- SB15134
- FCH1385698
- AX8245132
- ST2406417
- 6-Bromo-4-fluoro-1H-indole (ACI)
- 6-Bromo-4-fluoro-indole
- SCHEMBL1021334
- DTXCID90596982
- 885520-59-2
- AKOS015898371
- SY114760
- MFCD07781550
- EN300-747122
- DTXSID10646231
- Z1269127261
- DS-2828
- DB-077954
- CS-W019408
- P10508
- MDL： MFCD07781550
- Inchi： 1S/C8H5BrFN/c9-5-3-7(10)6-1-2-11-8(6)4-5/h1-4,11H
- InChI Key： VTODDAKQRGKCGF-UHFFFAOYSA-N
- SMILES： FC1C2=C(NC=C2)C=C(Br)C=1

Computed Properties

Exact Mass: 212.95894g/mol
Monoisotopic Mass: 212.95894g/mol
Isotope Atom Count: 0
Hydrogen Bond Donor Count: 1
Hydrogen Bond Acceptor Count: 1
Heavy Atom Count: 11
Rotatable Bond Count: 0
Complexity: 153
Covalently-Bonded Unit Count: 1
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count : 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Topological Polar Surface Area: 15.8
XLogP3: 2.8

Experimental Properties

Density: 1.750±0.06 g/cm3 (20 oC 760 Torr),
Solubility: Very slightly soluble (0.17 g/l) (25 o C),

6-Bromo-4-fluoro-1H-indole Security Information

Signal Word：Warning
Hazard Statement： H315-H319-H335
Warning Statement： P261-P305+P351+P338
Storage Condition：Inert atmosphere,2-8°C

6-Bromo-4-fluoro-1H-indole Pricemore >>

Related Categories	No.	Product Name	Cas No.	Purity	Specification	Price	update time
SHANG HAI XIAN DING Biotechnology Co., Ltd.	B-AC451-250mg	6-Bromo-4-fluoro-1H-indole	885520-59-2	98%	250mg	1979CNY	2021-05-08
SHANG HAI XIAN DING Biotechnology Co., Ltd.	B-AC451-100mg	6-Bromo-4-fluoro-1H-indole	885520-59-2	98%	100mg	936CNY	2021-05-08
Matrix Scientific	126791-1g	6-Bromo-4-fluoro-1H-indole, >95%	885520-59-2	>95%	1g	$1764.00	2023-09-09
SHANG HAI MAI KE LIN SHENG HUA Technology Co., Ltd.	B848437-100mg	6-Bromo-4-fluoro-1H-indole	885520-59-2	98%	100mg	1,105.20	2021-05-17
SHANG HAI XIAN DING Biotechnology Co., Ltd.	B-AC451-1g	6-Bromo-4-fluoro-1H-indole	885520-59-2	98%	1g	3480.0CNY	2021-08-04
SHANG HAI XIAN DING Biotechnology Co., Ltd.	B-AC451-200mg	6-Bromo-4-fluoro-1H-indole	885520-59-2	98%	200mg	831.0CNY	2021-08-04
SHANG HAI XIAN DING Biotechnology Co., Ltd.	B-AC451-50mg	6-Bromo-4-fluoro-1H-indole	885520-59-2	98%	50mg	333.0CNY	2021-08-04
TRC	B804275-1mg	6-Bromo-4-fluoro-1H-indole	885520-59-2		1mg	$ 50.00	2022-06-06
TRC	B804275-2mg	6-Bromo-4-fluoro-1H-indole	885520-59-2		2mg	$ 65.00	2022-06-06
TRC	B804275-10mg	6-Bromo-4-fluoro-1H-indole	885520-59-2		10mg	$ 95.00	2022-06-06

6-Bromo-4-fluoro-1H-indole Production Method

Production Method 1

502496-34-6

18503-89-4

885520-59-2

Reaction Conditions

1.1 Reagents: Triethylamine Solvents: Dimethylformamide ; 2 h, 130 °C
1.2 Reagents: Iron , Silica Solvents: Acetic acid , Toluene ; 30 min, rt → 100 °C

Reference

Discovery and structure-activity relationships of N-aryl 6-aminoquinoxalines as potent PFKFB3 kinase inhibitors

Boutard, Nicolas ; Bialas, Arkadiusz; Sabiniarz, Aleksandra ; Guzik, Pawel ; Banaszak, Katarzyna; et al, ChemMedChem, 2019, 14(1), 169-181

6-Bromo-4-fluoro-1H-indole Raw materials

6-Bromo-4-fluoro-1H-indole Preparation Products

6-Bromo-4-fluoro-1H-indole (885520-59-2)

6-Bromo-4-fluoro-1H-indole Suppliers

Suzhou Senfeida Chemical Co., Ltd

Gold Member

Audited Supplier

(CAS:885520-59-2)6-BROMO-4-FLUORO INDOLE

Order Number:sfd4364

Stock Status:in Stock

Quantity:200kg

Purity:99.9%

Pricing Information Last Updated:Friday, 19 July 2024 14:33

Price ($):discuss personally

Email:[email protected]

Product Official Link

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Related Categories

Solvents and Organic Chemicals Organic Compounds Organoheterocyclic compounds Indoles and derivatives Indoles

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