Production Method 1

871-78-3

Reaction Conditions

1.1 Catalysts: Iron oxide (Fe3O4) ,  Silver ,  Sodium lignosulfonate ;  0.5 h, rt

Reference

Fabrication of silver nanoparticles immobilized on magnetic lignosulfonate: Evaluation of its catalytic activity in the N-acetylation reactions and investigation of its anti-cutaneous squamous cell carcinoma effects

Zhao, Zunjiang; et al, International Journal of Biological Macromolecules, 2023, 250,

Production Method 2

13483-16-4

871-78-3

Reaction Conditions

1.1 5 min, 25 °C

Reference

Chemoselective acylation of amines, thiols, and phenols using 2,4,6-triacyloxy-1,3,5-triazine (TAT) as a new and effective reagent under mild condition

Gholap, Somnath S.; et al, Journal of the Indian Chemical Society, 2009, 86(2), 179-182

Production Method 3

871-78-3

Reaction Conditions

1.1 Reagents: Aluminum chloride ;  8 min

Reference

Study on synthesis of N,N,N',N'-Tetraacetylethylenediamine under microwave irradiation

Jing, Qi; et al, Shihua Jishu Yu Yingyong, 2003, 21(4), 256-258

Production Method 4

871-78-3

Reaction Conditions

1.1 Catalysts: Aluminum chloride ;  8 min

Reference

Primary study on synthesis of tetraacetylethylenediamine under microwave irradiation

Deng, Yu; et al, Pige Huagong, 2003, 20(2), 26-30

Production Method 5

871-78-3

Reaction Conditions

1.1 Catalysts: Iodine ;  2 min, rt
1.2 Reagents: Sodium thiosulfate Solvents: Water

Reference

Mild and Useful Method for N-Acylation of Amines

Phukan, Kandarpa; et al, Synthetic Communications, 2009, 39(15), 2694-2701

Production Method 6

10230-68-9

871-78-3

Reaction Conditions

Reference

Synthesis of β-nitro enamines

Tokumitsu, Takao; et al, Nippon Kagaku Kaishi, 1983, (1), 88-93

Production Method 7

10543-57-4

871-78-3

Reaction Conditions

1.1 Reagents: Sodium bicarbonate ,  Magnesium oxide ,  Hydrogen peroxide ;  8 h, 50 - 65 °C

Reference

Removing polysaccharides-and saccharides-related coloring impurities in alkyl polyglycosides by bleaching with the H2O2/TAED/NaHCO3 system

Yanmei, Liu; et al, Carbohydrate Polymers, 2014, 112, 416-421

Production Method 8

871-78-3

Reaction Conditions

1.1 Catalysts: Zirconium dioxide ,  Yttrium sesquioxide Solvents: Acetonitrile

Reference

Yttria-zirconia based Lewis acid: an efficient and chemoselective catalyst for acylation reactions

Kumar, Pradeep; et al, Synlett, 2001, (2), 206-209

Production Method 9

871-78-3

Reaction Conditions

1.1 Solvents: Water
1.2 220 °C

Reference

Imidazoles. 84. Synthesis of metronidazole from ethylene diamine

Kraft, M. Ya.; et al, Khimiko-Farmatsevticheskii Zhurnal, 1989, 23(10), 1246-8

Production Method 10

918-00-3

871-78-3

Reaction Conditions

1.1 Solvents: Hexane

Reference

1,1,1-Trichloropropanone: a mild, selective acetylating agent

Salim, Jose Roberto; et al, Synthetic Communications, 1989, 19(7-8), 1181-7

Production Method 11

871-78-3

Reaction Conditions

1.1 Reagents: Potassium tert-butoxide Catalysts: (OC-6-64)-[6-[[Bis(1,1-dimethylethyl)phosphino-κP]methyl]-N-(phenylmethyl)-2-pyr… Solvents: tert-Butyl methyl ether ;  5 min, rt
1.2 Solvents: tert-Butyl methyl ether ;  20 h, 70 °C

Reference

Near-Ambient-Temperature Dehydrogenative Synthesis of the Amide Bond: Mechanistic Insight and Applications

Kar, Sayan ; et al, ACS Catalysis, 2021, 11(12), 7383-7393

Production Method 12

871-78-3

Reaction Conditions

1.1 Reagents: Water Catalysts: Copper oxide (CuO) ;  2 h, 180 °C

Reference

Amide exchange reaction: a simple and efficient CuO catalyst for diacetamide synthesis

Li, Qinghe; et al, RSC Advances, 2016, 6(47), 40890-40894

Production Method 13

1001-53-2

830-03-5

871-78-3

Reaction Conditions

Reference

Monoacylation of symmetrical diamines

Jacobson, Alan R.; et al, Journal of Organic Chemistry, 1987, 52(12), 2592-4

Production Method 14

830-03-5

871-78-3

Reaction Conditions

Reference

Monoacylation of symmetrical diamines

Jacobson, Alan R.; et al, Journal of Organic Chemistry, 1987, 52(12), 2592-4

Production Method 15

871-78-3

871-78-3

Reaction Conditions

1.1 Reagents: Cobalt dibromide Solvents: Acetonitrile ,  2,2-Dimethoxypropane ;  heated; reflux

Reference

Synthesis and spectroscopic studies of the complexes of ethylenebis(acetamide) with some first row transition metal ions

Hussain, Izhar, Journal of the Chemical Society of Pakistan, 2007, 29(6), 605-610

N,N'-Diacetylethylenediamine Raw materials

• Mikon ATC
• Triacetyl Cyanurate
• N,N'-Diacetylethylenediamine
• 1-nitropropan-2-one
• N-(2-Aminoethyl)acetamide
• 4-Nitrophenyl acetate
• 1,1,1-Trichloroacetone

N,N'-Diacetylethylenediamine Preparation Products

• N,N'-Diacetylethylenediamine (871-78-3)

• 1. An amorphous lanthanum–iridium solid solution with an open structure for efficient water splitting?
  Wei Sun,Chenglong Ma,Xinlong Tian,Jianjun Liao,Ji Yang,Chengjun Ge,Weiwei Huang J. Mater. Chem. A, 2020,8, 12518-12525
• 2. An approach to biodegradable star polymeric architectures using disulfide coupling?
  Jingquan Liu,Huiyun Liu,Zhongfan Jia,Volga Bulmus,Thomas P. Davis Chem. Commun., 2008, 6582-6584
• 3. An amino group functionalized metal–organic framework as a luminescent probe for highly selective sensing of Fe3+ ions?
  Zhonghua Xiang,Chuanqi Fang,Sanhua Leng,Dapeng Cao J. Mater. Chem. A, 2014,2, 7662-7665
• 4. An aqueous ammonia sensor based on an inkjet-printed polyaniline nanoparticle-modified electrode
  Karl Crowley,Eimer O'Malley,Aoife Morrin,Malcolm R. Smyth,Anthony J. Killard Analyst, 2008,133, 391-399
• 5. Alumina coating on 5 V lithium cobalt fluorophosphate cathode material for lithium secondary batteries – synthesis and electrochemical properties?
  S. Amaresh,K. Karthikeyan,K. J. Kim,Y. S. Lee RSC Adv., 2014,4, 23107-23115

• Solvents and Organic Chemicals Organic Compounds Organic acids and derivatives Carboxylic acids and derivatives Carboxylic acid derivatives Carboxylic acid amides
• Solvents and Organic Chemicals Organic Compounds Amines/Sulfonamides

• 141998-21-2(Acetamide, N-[2-[[2-[(2-aminoethyl)amino]ethyl]amino]ethyl]-)
• 1001-53-2(N-(2-Aminoethyl)acetamide)
• 355115-87-6(DIGLYCYLETHYLENEDIAMINE, DIHYDROCHLORIDE SALT)
• 2098070-20-1(2-(3-(Pyridin-3-yl)-1H-pyrazol-1-yl)acetimidamide)
• 2680771-01-9(4-cyclopentyl-3-{(prop-2-en-1-yloxy)carbonylamino}butanoic acid)
• 1444113-98-7(N-(3-cyanothiolan-3-yl)-2-[(2,2,2-trifluoroethyl)sulfanyl]pyridine-4-carboxamide)
• 332062-08-5(Fmoc-S-3-amino-4,4-diphenyl-butyric acid)
• 1270529-38-8(1,2,3,4,5,6-Hexahydro-[2,3]bipyridinyl-6-ol)
• 941977-17-9(N'-(3-chloro-2-methylphenyl)-N-2-(dimethylamino)-2-(naphthalen-1-yl)ethylethanediamide)
• 2138166-62-6(2,2-Difluoro-3-[methyl(2-methylbutyl)amino]propanoic acid)