Production Method 1

76-00-6

918-00-3

Reaction Conditions

1.1 Reagents: Sulfuric acid ,  Sodium dichromate Solvents: Acetic acid

Reference

Selected methods for the oxidation of 1,1,1-trichloro-2-alkanols. An efficient modification using chromic acid

Gallina, Carlo; Giordano, Cesare, Synthesis, 1989, (6), 466-8

Production Method 2

100-52-7

16586-14-4

918-00-3

Reaction Conditions

1.1 Catalysts: Dibenzo-18-crown-6 Solvents: Acetonitrile

Reference

Trichloromethylation of carbonyl compounds in the presence of crown ethers

Kyazimov, A. S.; Abdullabekov, I. M.; Karaev, S. F., Zhurnal Organicheskoi Khimii, 1988, 24(8), 1615-17

Production Method 3

918-00-3

Reaction Conditions

1.1 Reagents: Chlorine

Reference

Chlorination of olefin chlorohydrins

Spasskaya, I. F.; Etlis, V. S.; Razuvaev, G. A., Zhurnal Obshchei Khimii, 1958, 28, 3004-8

Production Method 4

77879-49-3

918-00-3

Reaction Conditions

1.1 Solvents: Carbon tetrachloride

Reference

Carbonyl ylides and carbenes from thermolysis of oxadiazolines. Substituent effects on intramolecular and intermolecular reactions of carbonyl ylides

Bekhazi, Michel; Warkentin, John, Canadian Journal of Chemistry, 1983, 61(3), 619-24

Production Method 5

128-09-6

918-00-3

Reaction Conditions

Reference

Chlorination of aliphatic ketones in methanol

Gallucci, R. R.; Going, R., Journal of Organic Chemistry, 1981, 46(12), 2532-8

Production Method 6

918-00-3

Reaction Conditions

1.1 Reagents: Sodium bicarbonate ,  Sodium chloride Solvents: Water ;  23 - 25 °C

Reference

Electrochemical chlorination of acetone

Malaev, V. G.; Ilyushin, V. A., Izvestiya Akademii Nauk SSSR, 1989, (2), 462-4

Production Method 7

918-00-3

Reaction Conditions

1.1 Reagents: Chlorine Solvents: Acetic acid ,  Acetone

Reference

1,1,1-Trichloropropanone: a mild, selective acetylating agent

Salim, Jose Roberto; Nome, Faruk; Rezende, Marcos Caroli, Synthetic Communications, 1989, 19(7-8), 1181-7

Production Method 8

14357-05-2

918-00-3

Reaction Conditions

Reference

Trichloromethylation reaction. Ring-chain tautomerism

Winston, Anthony; Sharp, John C.; Atkins, Kenneth E.; Battin, Dale E., Journal of Organic Chemistry, 1967, 32(7), 2166-71

Production Method 9

76-00-6

918-00-3

Reaction Conditions

Reference

Synthesis by oxidation of heterosubstituted alkanes

von Angerer, S., Science of Synthesis, 2005, 26, 39-126

Production Method 10

344417-75-0

918-00-3

Reaction Conditions

Reference

Generation and chemical properties of dicyclopropylcarbene. Ring expansion, chlorine abstraction, carbon-hydrogen bond insertion, and alkene addition reactions

Bekhazi, Michel; Risbood, Prabhakar A.; Warkentin, John, Journal of the American Chemical Society, 1983, 105(17), 5675-9

Production Method 11

918-00-3

Reaction Conditions

Reference

Ozonolyses of O-alkylated ketoximes in the presence of carbonyl groups. A facile access to ozonides

Griesbaum, Karl; Liu, Xuejun; Kassiaris, Athanassios; Scherer, Martin, Liebigs Annalen/Recueil, 1997, (7), 1381-1390

Production Method 12

918-00-3

Reaction Conditions

Reference

Chlorination of acetone in the presence of acid and base catalysts

Bugrova, L. V.; Rudnev, G. K.; Khristich, A. I.; Radchenko, V. I.; Mishchenko, L. F., Zhurnal Prikladnoi Khimii (Sankt-Peterburg, 1973, 46(7), 1529-33

1,1,1-Trichloroacetone Raw materials

• 1,1,1-trichloropropan-2-ol
• 1-chloropyrrolidine-2,5-dione
• 1,3,4-OXADIAZOLE, 2,5-DIHYDRO-2-METHOXY-2,5,5-TRIMETHYL-
• 2,2-Dicyclopropyl-2,5-dihydro-5-methoxy-5-methyl-1,3,4-oxadiazole
• Benzaldehyde
• Acetic acid,2,2,2-trichloro-, ion(1-)
• Acetic acid, 2,2,2-trichloro-, potassium salt (1:1)

1,1,1-Trichloroacetone Preparation Products

• 1,1,1-Trichloroacetone (918-00-3)

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• Solvents and Organic Chemicals Organic Compounds Organic oxygen compounds Organooxygen compounds Ketones
• Solvents and Organic Chemicals Organic Compounds Organic oxygen compounds Organooxygen compounds Carbonyl compounds Ketones
• Solvents and Organic Chemicals Organic Compounds Aldehyde/Ketone

• 31422-61-4(2-Propanone,tetrachloro- (9CI))
• 123107-20-0(2-Propanone, 1,1,1-trichloro-, conjugate acid (9CI))
• 861255-82-5(2-Propanone,1,1,1-trichloro-, radical ion(1+) (9CI))
• 62951-70-6(Titanium, tetrachloro(2-propanone)-)
• 921-03-9(1,1,3-Trichloroacetone)
• 16995-35-0(2-Propanone,1,1,1,3-tetrachloro-)
• 72497-18-8(1,1,1-Trichloroacetone)
• 30605-38-0(2-Propanone, dichloro-)
• 1768-31-6(Pentachloroacetone)
• 2098070-20-1(2-(3-(Pyridin-3-yl)-1H-pyrazol-1-yl)acetimidamide)