Production Method 1

128071-75-0

84199-57-5

Reaction Conditions

1.1 Solvents: Tetrahydrofuran ;  0 - 5 °C

Reference

Silver-catalysed intramolecular cyclisation of 2-alkynylacetophenones and 3-acetyl-2-alkynylpyridines in the presence of ammonia

Dell'Acqua, Monica; Abbiati, Giorgio; Arcadi, Antonio; Rossi, Elisabetta, Organic & Biomolecular Chemistry, 2011, 9(22), 7836-7848

Production Method 2

128071-75-0

676-58-4

84199-57-5

Reaction Conditions

1.1 Solvents: Tetrahydrofuran ;  0 - 5 °C; 0.5 h, 0 - 5 °C
1.2 Reagents: Ammonium chloride Solvents: Water

Reference

Approach to 5-substituted 6,7,8,9-tetrahydro-5H-pyrido[3,2-c]azepines

Subota, Andrii I.; Artamonov, Oleksiy S.; Gorlova, Alina; Volochnyuk, Dmitriy M.; Grygorenko, Oleksandr O., Tetrahedron Letters, 2017, 58(20), 1989-1991

Production Method 3

626-05-1

84199-57-5

Reaction Conditions

1.1 Reagents: Lithium diisopropylamide Solvents: Tetrahydrofuran

Reference

Migration of lithium in a series of pyridines: double catalysis and reforming. Access to derivatives of 2-bromo-3-lithiopyridine and 4-bromo-2-halo-3-lithiopyridines

Mallet, Marc; Branger, Gilles; Marsais, Francis; Queguiner, Guy, Journal of Organometallic Chemistry, 1990, 382(3), 319-32

Production Method 4

128071-75-0

676-58-4

84199-57-5

Reaction Conditions

1.1 Solvents: Tetrahydrofuran ;  0 °C; rt
1.2 Reagents: Ammonium chloride Solvents: Water

Reference

Phosphine- and water-promoted pentannulative aldol reaction

Satpathi, Bishnupada; Dutta, Lona; Ramasastry, S. S. V., Organic & Biomolecular Chemistry, 2019, 17(6), 1547-1551

Production Method 5

128071-75-0

84199-57-5

Reaction Conditions

1.1 Solvents: Diethyl ether ,  Butyl ether ;  -78 °C; -78 °C → 0 °C; 3 h, 0 °C
1.2 Reagents: Ammonium chloride Solvents: Water

Reference

One-Pot Asymmetric Synthesis of Alkylidene 1-Alkylindan-1-ols Using Bronsted Acid and Palladium Catalysis

Faggyas, Reka J.; Calder, Ewen D. D.; Wilson, Claire; Sutherland, Andrew, Journal of Organic Chemistry, 2017, 82(21), 11585-11593

Production Method 6

84199-61-1

84199-57-5

Reaction Conditions

1.1 Reagents: Sodium borohydride Solvents: Methanol ;  0 °C; rt
1.2 Reagents: Ammonium chloride Solvents: Water

Reference

Morita-Baylis-Hillman Reaction of β,β-Disubstituted Enones: Enantioselective Organocatalytic Approach for the Synthesis of Cyclopenta[b]annulated Arenes and Heteroarenes

Satpathi, Bishnupada ; Ramasastry, S. S. V., Angewandte Chemie, 2016, 55(5), 1777-1781

Production Method 7

109-04-6

84199-57-5

Reaction Conditions

1.1 Catalysts: Lithium diisopropylamide

Reference

Regioselective synthesis and applications of an α-bromopyridine carbanion. Opening of the pyridine ring resulting from nucleophilic attack

Marsais, Francis; Laperdrix, Bruno; Guengoer, Timur; Mallet, Marc; Queguiner, Guy, Journal of Chemical Research, 1982, (10), 278-9

1-(2-bromopyridin-3-yl)ethanol Raw materials

• 2,6-Dibromopyridine
• 2-Bromonicotinaldehyde
• 2-Bromopyridine
• Methylmagnesium Chloride (3M in THF)
• 1-(2-bromopyridin-3-yl)ethan-1-one

1-(2-bromopyridin-3-yl)ethanol Preparation Products

• 1-(2-bromopyridin-3-yl)ethanol (84199-57-5)

• 1. Evidence that the availability of an allylic hydrogen governs the regioselectivity of the Wacker oxidation
  Matthew J. Gaunt,Jinquan Yu,Jonathan B. Spencer Chem. Commun., 2001, 1844-1845
• 2. Fate of Sb(v) and Sb(iii) species along a gradient of pH and oxygen concentration in the Carnoulès mine waters (Southern France)
  Eléonore Resongles,Corinne Casiot,Fran?oise Elbaz-Poulichet,Rémi Freydier,Odile Bruneel,Christine Piot,Sophie Delpoux,Aurélie Volant,Angélique Desoeuvre Environ. Sci.: Processes Impacts, 2013,15, 1536-1544
• 3. Excitation dependent bidirectional electron transfer in phthalocyanine-functionalised MoS2 nanosheets?
  Christopher J. Harrison,Kyle J. Berean,Enrico Della Gaspera,Jian Zhen Ou,Richard B. Kaner,Kourosh Kalantar-zadeh,Torben Daeneke Nanoscale, 2016,8, 16276-16283
• 4. Excitation energies from ground-state density-functionals by means of generator coordinates
  A. B. F. da Silva,K. Capelle Phys. Chem. Chem. Phys., 2009,11, 4564-4569
• 5. Essential effect of the electrolyte on the mechanical and chemical degradation of LiNi0.8Co0.15Al0.05O2 cathodes upon long-term cycling??
  Xiaoming Liu,Zachary D. Hood,Wangda Li,Donovan N. Leonard,Arumugam Manthiram,Miaofang Chi J. Mater. Chem. A, 2021,9, 2111-2119

• Solvents and Organic Chemicals Organic Compounds Organoheterocyclic compounds Pyridines and derivatives 2-halopyridines
• Solvents and Organic Chemicals Organic Compounds Organoheterocyclic compounds Pyridines and derivatives Halopyridines 2-halopyridines

• 139042-62-9(1-(6-bromopyridin-3-yl)ethanol)
• 139042-61-8(2-(6-bromopyridin-3-yl)propan-2-ol)
• 2227862-24-8((1R)-1-(2-bromopyridin-3-yl)ethan-1-ol)
• 909532-39-4(2-(2-Bromopyridin-3-yl)propan-2-ol)
• 153473-73-5(3-Pyridinemethanol, 2-bromo-α-(1-methylethyl)-)
• 2490314-38-8((1S)-1-(6-bromopyridin-3-yl)ethan-1-ol hydrochloride)
• 139163-63-6((1S)-1-(6-Bromopyridin-3-yl)ethan-1-ol)
• 1642544-74-8(1-(2-Bromopyridin-3-yl)-1-phenylethan-1-ol)
• 2229585-07-1(O-1-(2-bromopyridin-3-yl)ethylhydroxylamine)
• 139163-64-7(R-(6-bromopyridin-3-yl)ethanol)