Cas no 82911-69-1 (Fmoc-OSu)

Fmoc-OSu (N-(3-Dimethylaminopropyl)-N'-ethoxycarbonyloxyosuccinimide) is a highly reactive coupling reagent for peptide synthesis, offering efficient and stable N-Fmoc removal under mild conditions. Its superior yield and minimal byproduct formation make it an ideal choice for researchers seeking to optimize their synthesis protocols with improved accuracy and reproducibility.
Fmoc-OSu structure
Fmoc-OSu structure
Product Name:Fmoc-OSu
CAS No:82911-69-1
MF:C19H15NO5
MW:337.326105356216
MDL:MFCD00010733
CID:60517
PubChem ID:24857201
Update Time:2025-08-25

Fmoc-OSu Chemical and Physical Properties

Names and Identifiers

    • N-(9-Fluorenylmethoxycarbonyloxy)succinimide
    • 1-(9H-Fluorenylmethoxycarbonyloxy)-2,5-pyrrolidinedione
    • FMOC-ONSu
    • N-(9-fluorenylmethoxycarbonyloxy)-succinimide
    • N-(9-Fluorenylmethyloxycarbonyl) oxysuccinimide
    • N-(9H-Fluoren-2-ylmethoxycarbonyloxy)succinimide
    • FMOC-OSU
    • 9-Fluorenylmethyl succinimidyl carbonate
    • N-[(9H-Fluoren-9-ylmethoxy)carbonyloxy]succinimide
    • (2,5-dioxopyrrolidin-1-yl) 9H-fluoren-9-ylmethyl carbonate
    • (9H-Fluoren-9-yl)methyl (2,5-dioxopyrrolidin-1-yl) carbonate
    • 1-{[(9H-Fluoren-9-ylmethoxy)carbonyl]-oxy}pyrrolidine-2,5-dione
    • Fmoc-OSu (9-Fluorenylmethyl succinimidyl carbonate)
    • FMOC-Succinimide
    • Carbonic Acid 9-Fluorenylmethyl N-Succinimidyl Ester
    • 9-Fluorenylmethyl N-Succinimidyl Carbonate
    • N-(Fmoc-oxy)succinimide
    • 9-Fluorenylmethyl-succinimidyl-carbonate
    • Fmoc N-hydroxysuccinimide ester
    • N-(9-Fluorenylmethoxycarbonyloxy) succinimide
    • 9-Fluorenylmethylsuccinimidyl carbonate
    • WMSUFWLPZLCIHP-UHFFFAOYSA-N
    • 2,5-PYRROLIDINEDIONE, 1-[[(9H-FLUOREN-9-YLMETHOXY)CARBONYL]OXY]-
    • (9h-fluoren-9-yl)methyl 2,5-dioxopyrrolidin-1-yl carbona
    • 2,5-Pyrrolidinedione, 1-[[(9H-fluoren-9-ylmethoxy)carbonyl]oxy]- (9CI)
    • (9H-Fluoren-9-yl)methyl succinimidyl carbonate
    • (Fluorenylmethoxycarbonyl)hydroxysuccinimide ester
    • 1-[[[(9H-Fluoren-9-yl)methoxy]carbonyl]oxy]pyrrolidine-2,5-dione
    • 2,5-Dioxopyrrolidin-1-yl (9H-fluoren-9-yl)methyl carbonate
    • 9-Fluorenylmethyl-N-hydroxysuccinimide
    • Fluorenylmethoxycarbonyl N-hydroxysuccinimide
    • Fmoc-N-hydroxysuccinimide
    • Fmoc-N-hydroxysuccinimide ester
    • N-(9H-Fluoren-9-ylmethoxycarbonyloxy)succinimide
    • N-Fmoc-succinimide
    • Succinimidyl (9-fluorenyl)methyl carbonate
    • Oprea1_282076
    • 1-({[(9H-Fluoren-9-yl)methoxy]carbonyl}oxy)pyrrolidine-2,5-dione
    • 1-[[(9H-FLUOREN-9-YLMETHOXY)CARBONYL]OXY]-2,5-PYRROLIDINEDIONE
    • M02861
    • MFCD00010733
    • CS-W008951
    • 82911-69-1
    • n-(9-fluorenylmethoxy-carbonyloxy)succinimide
    • [(9H-fluoren-9-ylmethoxy) carbonyl]oxy-2,5-pyrrolidinedione
    • F0239
    • NS00004494
    • 9-fluorenylmethyl-n-succinimidyl carbonate
    • Fmoc-OSu N-(9-Fluorenylmethoxycarbonyloxy)succinimide
    • Fmoc N-hydroxysuccinimide ester, >=98.0% (HPLC)
    • 2,5-Pyrrolidinedione, 1-(((9H-fluoren-9-ylmethoxy)carbonyl)oxy)-
    • (2,5-Dioxopyrrolidin-1-yl)-9H-fluoren-9-ylmethyl carbonate
    • N-(9-fluorenyl-methoxycarbonyloxy)succinimide
    • Maybridge3_003020
    • AC-7857
    • AD7AUS3GKT
    • 2,5-dioxoazolidinyl (fluoren-9-ylmethoxy)formate
    • BP-20599
    • SCHEMBL141134
    • BCP10407
    • Carbonic acid 2,5-dioxo-pyrrolidin-1-yl ester 9H-fluoren-9-ylmethyl ester
    • SR-01000640502-1
    • AKOS000528224
    • EN300-68359
    • (9h-fluoren-9-yl)methyl 2,5-dioxopyrrolidin-1-yl carbonate
    • AB01046
    • IDI1_014407
    • 1-([(9H-Fluoren-9-ylmethoxy)carbonyl]oxy)-2,5-pyrrolidinedione #
    • CBDivE_000404
    • succinimidyl 9-fluorenylmethyl carbonate
    • EC 433-520-5
    • HMS1439J06
    • 1-{[(9H-fluoren-9-ylmethoxy)carbonyl]oxy}pyrrolidine-2,5-dione
    • C19H15NO5
    • N-{[(9H-fluoren-9-yl)methoxy]carbonyl}oxysuccinimide
    • CCG-2040
    • CARBONIC ACID, 2,5-DIOXO-1-PYRROLIDINYL 9H-FLUOREN-9-YLMETHYL ESTER
    • FmocOSU
    • N-[(9-fluorenyl)-methoxycarbonyloxy]-succinimide
    • FT-0621661
    • AM20041222
    • STR07750
    • [(9H-fluoren-9-ylmethoxy)carbonyl]oxy-2,5-pyrrolidinedione
    • Fmoc-OSu, 96%
    • HY-79647
    • DTXSID90232090
    • STK368257
    • 2,5-dioxopyrrolidin-1-yl 9H-fluoren-9-ylmethyl carbonate
    • Fmoc-OSu;9-Fluorenylmethyl succinimidyl carbonate;1-(9H-Fluorenylmethoxycarbonyloxy)2,5-pyrrolidinedione
    • Fmoc-OSu
    • MDL： MFCD00010733
    • Inchi： 1S/C19H15NO5/c21-17-9-10-18(22)20(17)25-19(23)24-11-16-14-7-3-1-5-12(14)13-6-2-4-8-15(13)16/h1-8,16H,9-11H2
    • InChI Key： WMSUFWLPZLCIHP-UHFFFAOYSA-N
    • SMILES： O=C(OCC1C2C(=CC=CC=2)C2C1=CC=CC=2)ON1C(=O)CCC1=O
    • BRN： 3569540

Computed Properties

  • Exact Mass: 337.09500
  • Monoisotopic Mass: 337.095023
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 0
  • Hydrogen Bond Acceptor Count: 5
  • Heavy Atom Count: 25
  • Rotatable Bond Count: 5
  • Complexity: 524
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • Surface Charge: 0
  • Tautomer Count: 3
  • XLogP3: 2.7
  • Topological Polar Surface Area: 72.9

Experimental Properties

  • Color/Form: White to Yellow Solid
  • Density: 1.3460 (rough estimate)
  • Melting Point: 153°C(dec.)(lit.)
  • Boiling Point: 150-153°C
  • Flash Point: 252.7±26.8 °C
  • Refractive Index: 1.5000 (estimate)
  • Solubility: Soluble in dimethyl sulfoxide and dimethyl formamide.
  • PSA: 72.91000
  • LogP: 2.95400
  • Solubility: Not determined
  • Sensitiveness: Moisture Sensitive
  • Vapor Pressure: 0.0±1.3 mmHg at 25°C

Fmoc-OSu Security Information

  • Symbol: GHS07 GHS09
  • Prompt：warning
  • Signal Word：Warning
  • Hazard Statement： H302,H317,H411
  • Warning Statement： P273,P280
  • Hazardous Material transportation number：UN 3077 9 / PGIII
  • WGK Germany：3
  • Hazard Category Code： 22-43-51/53
  • Safety Instruction： S22-S24/25-S26/37/39
  • FLUKA BRAND F CODES：10-21
  • Hazardous Material Identification： Xi
  • Risk Phrases：R36/37/38
  • HazardClass：9
  • Storage Condition：0-10°C
  • PackingGroup：III

Fmoc-OSu Customs Data

  • HS CODE：29251995
  • Customs Data：

    China Customs Code:

    2925190090

    Overview:

    2925190090 Other imides and their derivative salts. VAT:17.0% Tax refund rate:9.0% Regulatory conditions:nothing MFN tariff:6.5% general tariff:30.0%

    Declaration elements:

    Product Name, component content, use to

    Summary:

    2925190090 other imides and their derivatives; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

Fmoc-OSu Pricemore >>

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Fmoc-OSu Production Method

Production Method 1

Reaction Conditions
Reference
N-(9-Fluorenylmethyloxycarbonyl)-oxysuccinimide
Raillard, Stephen P., e-EROS Encyclopedia of Reagents for Organic Synthesis, 2002, 1, 1-2

Production Method 2

Reaction Conditions
1.1 Solvents: Chloroform
Reference
Effective orthogonal protection of L-ornithine as amino acyl component for amino acylation of 5'-O-pivaloyl nucleosides. Synthesis of Bz(NO2)-Orn(Boc)-OCH2CN by the Fmoc-strategy
Bayryamov, Stanislav G.; et al, Comptes Rendus de l'Academie Bulgare des Sciences, 2011, 64(2), 211-218

Production Method 3

Reaction Conditions
1.1 Solvents: Chloroform ;  overnight, rt
Reference
The two pathways for effective orthogonal protection of L-ornithine, for amino acylation of 5'-O-Pivaloyl nucleosides, describe the general and important role for the successful imitation, during the synthesis of the model substrates for the ribosomal mimic reaction
Bayryamov, Stanislav G.; et al, Protein & Peptide Letters, 2010, 17(7), 889-898

Production Method 4

Reaction Conditions
1.1 Reagents: Triethylamine Solvents: Acetonitrile
Reference
A convenient method for the synthesis of mixed succinimido carbonates from alcohols, using disuccinimido carbonate. Application to alkoxycarbonylation of amino acids
Kundu, Bijoy; et al, Journal of Chemical Research, 1994, (11),

Production Method 5

Reaction Conditions
Reference
N-(9-Fluorenylmethyloxycarbonyl)-oxysuccinimide
Raillard, Stephen P., e-EROS Encyclopedia of Reagents for Organic Synthesis, 2002, 1, 1-2

Production Method 6

Reaction Conditions
Reference
Introduction of 9-fluorenylmethyloxycarbonyl, trichloroethoxycarbonyl, and benzyloxycarbonyl amine protecting groups into O-unprotected hydroxy amino acids using succinimidyl carbonates
Paquet, Alenka, Canadian Journal of Chemistry, 1982, 60(8), 976-80

Production Method 7

Reaction Conditions
1.1 Solvents: Acetone ;  overnight, rt
2.1 Solvents: Chloroform
Reference
Effective orthogonal protection of L-ornithine as amino acyl component for amino acylation of 5'-O-pivaloyl nucleosides. Synthesis of Bz(NO2)-Orn(Boc)-OCH2CN by the Fmoc-strategy
Bayryamov, Stanislav G.; et al, Comptes Rendus de l'Academie Bulgare des Sciences, 2011, 64(2), 211-218

Production Method 8

Reaction Conditions
1.1 Solvents: Acetone ;  overnight, rt
2.1 Solvents: Chloroform ;  overnight, rt
Reference
The two pathways for effective orthogonal protection of L-ornithine, for amino acylation of 5'-O-Pivaloyl nucleosides, describe the general and important role for the successful imitation, during the synthesis of the model substrates for the ribosomal mimic reaction
Bayryamov, Stanislav G.; et al, Protein & Peptide Letters, 2010, 17(7), 889-898

Production Method 9

Reaction Conditions
1.1 Reagents: Pyridine Solvents: Tetrahydrofuran ;  3 h, 30 °C
2.1 Reagents: Triethylamine Solvents: Tetrahydrofuran ;  1 h, rt
Reference
Study of 9-fluorenylmethoxycarbonyl amino protective agents
Xu, Yan-jie; et al, Jingxi Huagong, 2004, 21(5), 352-355

Fmoc-OSu Raw materials

Fmoc-OSu Preparation Products

Fmoc-OSu Suppliers

Suzhou Senfeida Chemical Co., Ltd
Gold Member
Audited Supplier Audited Supplier
(CAS:82911-69-1)N-(9-Fluorenylmethoxycarbonyloxy)succinimide
Order Number:1638440;sfd21312
Stock Status:in Stock
Quantity:Company Customization/200kg
Purity:98%/99.9%
Pricing Information Last Updated:Monday, 14 April 2025 21:49
Price ($):discuss personally
Amadis Chemical Company Limited
Gold Member
Audited Supplier Audited Supplier
(CAS:82911-69-1)Fmoc-OSu
Order Number:A22826
Stock Status:in Stock
Quantity:1kg
Purity:99%
Pricing Information Last Updated:Friday, 30 August 2024 04:14
Price ($):210.0
Tiancheng Chemical (Jiangsu) Co., Ltd
Gold Member
Audited Supplier Audited Supplier
(CAS:82911-69-1)芴甲氧羰酰琥珀酰亞胺
Order Number:LE1638440
Stock Status:in Stock
Quantity:25KG,200KG,1000KG
Purity:99%
Pricing Information Last Updated:Friday, 20 June 2025 12:30
Price ($):discuss personally

Fmoc-OSu Spectrogram

GC-MS
GC-MS
13C NMR
13C NMR
1H NMR 300 MHz DMSO
1H NMR

Fmoc-OSu Related Literature

Related Categories

82911-69-1 (Fmoc-OSu) Related Products

Recommended suppliers
Suzhou Senfeida Chemical Co., Ltd
(CAS:82911-69-1)N-(9-Fluorenylmethoxycarbonyloxy)succinimide
1638440;sfd21312
Purity:98%/99.9%
Quantity:Company Customization/200kg
Price ($):Inquiry/Inquiry
Email
Amadis Chemical Company Limited
(CAS:82911-69-1)Fmoc-OSu
A22826
Purity:99%
Quantity:1kg
Price ($):210.0
Email