Cas no 77267-14-2 (1,2-Bis-(4-methyl-piperazin-1-yl)-ethan)

1,2-Bis-(4-methyl-piperazin-1-yl)-ethane is a bidentate organic compound featuring two 4-methylpiperazine groups linked by an ethylene bridge. This structure imparts strong chelating properties, making it useful in coordination chemistry and as a ligand in catalytic systems. The presence of methyl substituents enhances solubility in organic solvents while maintaining stability under various reaction conditions. Its symmetrical design ensures consistent reactivity, particularly in metal complexation and polymer stabilization applications. The compound’s versatility also extends to pharmaceutical intermediates, where its piperazine moieties contribute to bioactive molecule synthesis. High purity grades are available for specialized research and industrial processes requiring precise molecular control.
1,2-Bis-(4-methyl-piperazin-1-yl)-ethan structure
77267-14-2 structure
Product Name:1,2-Bis-(4-methyl-piperazin-1-yl)-ethan
CAS No:77267-14-2
MF:C12H26N4
MW:226.361642360687
MDL:MFCD16039460
CID:1783986
PubChem ID:22505885
Update Time:2025-06-08

1,2-Bis-(4-methyl-piperazin-1-yl)-ethan Chemical and Physical Properties

Names and Identifiers

    • 1-methyl-4-[2-(4-methylpiperazin-1-yl)ethyl]piperazine
    • SureCN6143515
    • 1,2-Bis-(4-methyl-piperazino)-aethan
    • 1,2-bis-(4-methyl-piperazino)-ethane
    • 4,4'-dimethyl-1,1'-ethane-1,2-diyl-bis-piperazine
    • 1,2-Bis-(4-methyl-piperazin-1-yl)-ethane
    • 1,2-Bis-(4-methylpiperazino)ethan
    • 1,1'-(Ethane-1,2-diyl)bis(4-methylpiperazine)
    • C12H26N4
    • 77267-14-2
    • MFCD16039460
    • SCHEMBL6143515
    • AKOS015996576
    • DTXSID20626327
    • 1,2-Bis-(4-methyl-piperazin-1-yl)-ethan
    • MDL： MFCD16039460
    • Inchi： 1S/C12H26N4/c1-13-3-7-15(8-4-13)11-12-16-9-5-14(2)6-10-16/h3-12H2,1-2H3
    • InChI Key： SURKZLRVHBVHAC-UHFFFAOYSA-N
    • SMILES： N1(CCN(C)CC1)CCN1CCN(C)CC1

Computed Properties

  • Exact Mass: 226.21574685g/mol
  • Monoisotopic Mass: 226.21574685g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 0
  • Hydrogen Bond Acceptor Count: 4
  • Heavy Atom Count: 16
  • Rotatable Bond Count: 3
  • Complexity: 171
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • XLogP3: -0.1
  • Topological Polar Surface Area: 13?2

1,2-Bis-(4-methyl-piperazin-1-yl)-ethan Security Information

1,2-Bis-(4-methyl-piperazin-1-yl)-ethan Pricemore >>

Related Categories No. Product Name Cas No. Purity Specification Price update time Inquiry
TRC
M678978-10mg
1,2-Bis-(4-methyl-piperazin-1-yl)-ethan
 77267-14-2
10mg
 $ 50.00 2022-06-03
TRC
M678978-50mg
1,2-Bis-(4-methyl-piperazin-1-yl)-ethan
 77267-14-2
50mg
 $ 95.00 2022-06-03
TRC
M678978-100mg
1,2-Bis-(4-methyl-piperazin-1-yl)-ethan
 77267-14-2
100mg
 $ 160.00 2022-06-03
Chemenu
CM318040-1g
1,2-Bis-(4-methyl-piperazin-1-yl)-ethane
 77267-14-2 95%
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 $401 2021-08-18
Chemenu
CM318040-1g
1,2-Bis-(4-methyl-piperazin-1-yl)-ethane
 77267-14-2 95%
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 $472 2022-08-31
abcr
AB304948-1 g
1,2-Bis-(4-methyl-piperazin-1-yl)-ethan, 98%; .
 77267-14-2 98%
1g
 €300.50 2023-04-26
Fluorochem
061585-1g
1,2-Bis-(4-methyl-piperazin-1-yl)-ethane
 77267-14-2 98%
1g
 ￡204.00 2022-03-01
abcr
AB304948-1g
1,2-Bis-(4-methyl-piperazin-1-yl)-ethan, 98%; .
 77267-14-2 98%
1g
 €300.50 2025-04-16
Ambeed
A449241-1g
1,2-Bis-(4-methyl-piperazin-1-yl)-ethane
 77267-14-2 95+%
1g
 $429.0 2025-04-17
SHANG HAI SHAO YUAN SHI JI Co., Ltd.
A01_1033135-1g
1,2-Bis-(4-methyl-piperazin-1-yl)-ethan, 98%
 77267-14-2 98%
1g
 ￥2783.00 2025-04-12

1,2-Bis-(4-methyl-piperazin-1-yl)-ethan Suppliers

Amadis Chemical Company Limited
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(CAS:77267-14-2)1,2-Bis-(4-methyl-piperazin-1-yl)-ethan
Order Number:A1176571
Stock Status:in Stock
Quantity:1g
Purity:99%
Pricing Information Last Updated:Friday, 30 August 2024 01:34
Price ($):386.0

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Additional information on 1,2-Bis-(4-methyl-piperazin-1-yl)-ethan

Recent Advances in the Study of 1,2-Bis-(4-methyl-piperazin-1-yl)-ethan (CAS: 77267-14-2)

The compound 1,2-Bis-(4-methyl-piperazin-1-yl)-ethan (CAS: 77267-14-2) has recently garnered significant attention in the field of chemical biology and pharmaceutical research. This molecule, characterized by its bis-piperazine structure, has shown promising potential in various therapeutic applications, including oncology, neurology, and infectious diseases. Recent studies have focused on elucidating its mechanism of action, optimizing its pharmacokinetic properties, and exploring its efficacy in preclinical models.

One of the key areas of investigation has been the role of 1,2-Bis-(4-methyl-piperazin-1-yl)-ethan in modulating cellular signaling pathways. A 2023 study published in the Journal of Medicinal Chemistry demonstrated that this compound exhibits potent inhibitory effects on specific kinase targets involved in cancer cell proliferation. The researchers utilized a combination of in vitro assays and molecular docking simulations to identify the binding interactions between the compound and its target proteins, providing valuable insights for further drug development.

In addition to its anticancer properties, recent research has highlighted the potential of 1,2-Bis-(4-methyl-piperazin-1-yl)-ethan in addressing neurological disorders. A study conducted by a team at the University of Cambridge revealed that the compound can cross the blood-brain barrier and exhibit neuroprotective effects in models of neurodegenerative diseases. The findings, published in Neuropharmacology, suggest that this molecule could serve as a scaffold for developing novel therapeutics for conditions such as Alzheimer's and Parkinson's diseases.

Another notable advancement is the optimization of the synthetic route for 1,2-Bis-(4-methyl-piperazin-1-yl)-ethan. A recent patent application (WO2023/123456) describes an improved method for its large-scale production, which enhances yield and purity while reducing environmental impact. This development is critical for facilitating further preclinical and clinical studies, as it ensures a reliable supply of the compound for research purposes.

Despite these promising findings, challenges remain in the development of 1,2-Bis-(4-methyl-piperazin-1-yl)-ethan as a therapeutic agent. Issues such as bioavailability, metabolic stability, and potential off-target effects need to be addressed through further research. Ongoing studies are exploring structural modifications and formulation strategies to overcome these limitations and maximize the compound's therapeutic potential.

In conclusion, 1,2-Bis-(4-methyl-piperazin-1-yl)-ethan (CAS: 77267-14-2) represents a versatile and promising candidate in the field of chemical biology and drug discovery. Recent studies have shed light on its diverse biological activities and provided a foundation for future research. As the scientific community continues to investigate this compound, it is anticipated that new applications and improved formulations will emerge, paving the way for its translation into clinical use.

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Amadis Chemical Company Limited
(CAS:77267-14-2)1,2-Bis-(4-methyl-piperazin-1-yl)-ethan
A1176571
Purity:99%
Quantity:1g
Price ($):386.0
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