Cas no 934-98-5 (2-(4-methylpiperazin-1-yl)ethan-1-amine)

2-(4-methylpiperazin-1-yl)ethan-1-amine structure

934-98-5 structure

Product Name:2-(4-methylpiperazin-1-yl)ethan-1-amine

CAS No:934-98-5

MF:C₇H₁₇N₃

MW:143.229981184006

MDL:MFCD03701701

CID:40329

PubChem ID:70284

Update Time:2024-10-26

2-(4-methylpiperazin-1-yl)ethan-1-amine Chemical and Physical Properties

Names and Identifiers

- 2-(4-Methylpiperazin-1-yl)ethylamine
- 1-(2-Aminoethyl)-4-methylpiperazine
- 1-(2-Aminoethyl)-4-Methyl-Piperazine
- 2-(4-Methylpiperazin-1-yl)ethanamine
- 2-(4-Methyl-piperazin-1-yl)-ethylamine
- 4-Methyl-1-piperazineethanamine
- 1-Piperazineethanamine,4-methyl
- 4-Methyl-1-piperazineethanamine (ACI)
- Piperazine, 1-(2-aminoethyl)-4-methyl- (6CI, 7CI, 8CI)
- 1-Methyl-4-(2-aminoethyl)piperazine
- 2-(4-Methyl-1-piperazinyl)ethanamine
- 2-(4-Methylpiperazin-1-yl)ethan-1-amine
- 2-(4-Methylpiperazino)ethanamine
- 4-(2-Aminoethyl)-1-methylpiperazine
- CS-W007512
- ALBB-005818
- STK500900
- 2-(4-methylpiperazin-1-yl)-ethanamine
- 2-(4-Methyl-1-piperazino)ethylamine Hydrochloride
- Q27157656
- 2-(4-methylpiperazin-1-yl) ethylamine
- DTXSID10239420
- 2-(4-methyl-piperazine-1-yl)-ethyl amine
- NS00039568
- 2-(4-methylpiperazin-1-yl)-ethylamine
- CHEBI:84290
- 2(4-methylpiperazin-1-yl)ethylamine
- AB15815
- DB-019466
- Piperazine 1-[2-aminoethyl]-4-methyl-
- SCHEMBL42017
- Z79BOY08I2
- EINECS 213-296-3
- SCHEMBL4480122
- 4-Methylpiperazine-1-ethylamine
- EN300-24106
- 2-(4-Methyl-piperazin-1-yl)-ethylamine, AldrichCPR
- A846010
- MFCD03701701
- UNII-Z79BOY08I2
- CCG-358157
- 2-(4-Methyl-1-piperazinyl)ethanamine #
- A2398
- 2-(4-METHYL-1-PIPERAZINYL)ETHYLAMINE
- DTXCID30161911
- F2187-2164
- AKOS000201108
- 1-(2-aminoethyl)-4-methyl piperazine
- Piperazine, 1-(2-aminoethyl)-4-methyl-
- SY032261
- Piperazine 1-(2-aminoethyl)-4-methyl-
- LF-0565
- J-506071
- 1-Piperazineethanamine, 4-methyl-
- 934-98-5
- 2-(4-methylpiperazin-1-yl)ethan-1-amine
- MDL： MFCD03701701
- Inchi： 1S/C7H17N3/c1-9-4-6-10(3-2-8)7-5-9/h2-8H2,1H3
- InChI Key： GOWUDHPKGOIDIX-UHFFFAOYSA-N
- SMILES： NCCN1CCN(C)CC1

Computed Properties

Exact Mass: 143.14200
Monoisotopic Mass: 143.142
Isotope Atom Count: 0
Hydrogen Bond Donor Count: 1
Hydrogen Bond Acceptor Count: 3
Heavy Atom Count: 10
Rotatable Bond Count: 2
Complexity: 86.9
Covalently-Bonded Unit Count: 1
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count : 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Surface Charge: 0
Tautomer Count: nothing
XLogP3: -0.9
Topological Polar Surface Area: 32.5A^2

Experimental Properties

Density: 0.956
Boiling Point: 215.4℃ at 760 mmHg
Flash Point: 83.3 °C
Refractive Index: 1.487
PSA: 32.50000
LogP: -0.23140
Sensitiveness: Air Sensitive

2-(4-methylpiperazin-1-yl)ethan-1-amine Security Information

Hazard Statement： Irritant
Hazardous Material transportation number：2735
Hazard Category Code： 36/37/38-22
Safety Instruction： S26-S36/37/39
Hazardous Material Identification：
Risk Phrases：R36/37/38
HazardClass：8
PackingGroup：Ⅲ

2-(4-methylpiperazin-1-yl)ethan-1-amine Customs Data

HS CODE：2933599090
Customs Data：

China Customs Code:
2933599090

Overview:

2933599090. Other compounds with pyrimidine ring in structure(Including other compounds with piperazine ring on the structure. VAT:17.0%. Tax refund rate:13.0%. Regulatory conditions:nothing. MFN tariff:6.5%. general tariff:20.0%

Declaration elements:

Product Name, component content, use to, Please indicate the appearance of Urotropine, 6- caprolactam please indicate the appearance, Signing date

Summary:

2933599090. other compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

2-(4-methylpiperazin-1-yl)ethan-1-amine Pricemore >>

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Fluorochem	030836-1g	2-(4-Methyl-piperazin-1-yl)-ethylamine	934-98-5	98%	1g	￡20.00	2022-03-01
Fluorochem	030836-5g	2-(4-Methyl-piperazin-1-yl)-ethylamine	934-98-5	98%	5g	￡65.00	2022-03-01
Fluorochem	030836-10g	2-(4-Methyl-piperazin-1-yl)-ethylamine	934-98-5	98%	10g	￡120.00	2022-03-01
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Alichem	A139000023-25g	4-Methyl-1-piperazineethanamine	934-98-5	97%	25g	363.70 USD	2021-06-01
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SHANG HAI YI EN HUA XUE JI SHU Co., Ltd.	R032692-250mg	2-(4-methylpiperazin-1-yl)ethan-1-amine	934-98-5	98%	250mg	￥27	2024-05-20
Ambeed	A245391-250mg	2-(4-Methylpiperazin-1-yl)ethanamine	934-98-5	97%	250mg	$10.0	2025-04-15
Ambeed	A245391-1g	2-(4-Methylpiperazin-1-yl)ethanamine	934-98-5	97%	1g	$13.0	2025-04-15

2-(4-methylpiperazin-1-yl)ethan-1-amine Production Method

Production Method 1

1484327-92-5

934-98-5

Reaction Conditions

1.1 Reagents: Hydrochloric acid Solvents: Methanol , 1,4-Dioxane ; 1 h, rt

Reference

: Synthesis and evaluation of chirally defined side chain variants of 7-chloro-4-aminoquinoline to overcome drug resistance in malaria chemotherapy

Dola, Vasantha Rao; Soni, Awakash; Agarwal, Pooja; Ahmad, Hafsa; Raju, Kanumuri Siva Rama; et al, Antimicrobial Agents and Chemotherapy, 2017, 61(3),

Production Method 2

874-77-1

934-98-5

Reaction Conditions

1.1 Reagents: Lithium aluminum hydride Solvents: Tetrahydrofuran ; 0 °C; 1 h, rt; cooled
1.2 Reagents: Sodium hydroxide Solvents: Water ; 20 min, cooled

Reference

: Phenyl-urea and phenyl-carbamate derivatives as inhibitors of protein aggregation

, World Intellectual Property Organization, , ,

Production Method 3

874-77-1

934-98-5

Reaction Conditions

1.1 Reagents: Lithium aluminum hydride Solvents: Diethyl ether , Tetrahydrofuran ; 0 °C; 24 h, rt; cooled
1.2 Reagents: Sodium hydroxide Solvents: Water ; 20 min, cooled

Reference

: 2,3-Dihydro-2-oxo-1H-benzimidazole-1-carboxamides with Selective Affinity for the 5-HT4 Receptor: Synthesis and Structure-Affinity and Structure-Activity Relationships of a New Series of Partial Agonist and Antagonist Derivatives

Tapia, Ines; Alonso-Cires, Luisa; Lopez-Tudanca, Pedro Luis; Mosquera, Ramon; Labeaga, Luis; et al, Journal of Medicinal Chemistry, 1999, 42(15), 2870-2880

Production Method 4

874-77-1

934-98-5

Reaction Conditions

1.1 Solvents: Diethyl ether

Reference

: Guanidines having antihypertensive activity. I. Dialkylaminoalkylamino-2-imidazolines

Najer, Henry; Giudicelli, Rene; Sette, Jacques, Bulletin de la Societe Chimique de France, 1962, 556, 556-9

Production Method 5

874-77-1

934-98-5

Reaction Conditions

1.1 Reagents: Lithium aluminum hydride Solvents: Diethyl ether , Tetrahydrofuran ; 0 °C; 1 h, 0 °C; 0 °C → rt; overnight, rt
1.2 Reagents: Sodium hydroxide Solvents: Water ; 20 min, rt

Reference

: New derivatives of quinoline-4-carboxylic acid with antiplasmodial activity

Hochegger, Patrick ; Faist, Johanna; Seebacher, Werner; Saf, Robert; Maeser, Pascal; et al, Bioorganic & Medicinal Chemistry, 2017, 25(7), 2251-2259

Production Method 6

4489-39-8

934-98-5

Reaction Conditions

1.1 Reagents: Hydrazine Solvents: Ethanol ; 24 h, reflux

Reference

: Structural optimizations and bioevaluation of N-substituted acridone derivatives as strong topoisomerase II inhibitors

Li, Zhi-Ying; Xu, Guang-Sen; Song, Yu-Liang; Li, Xun, Bioorganic Chemistry, 2022, 119,

Production Method 7

1484327-92-5

934-98-5

Reaction Conditions

1.1 Reagents: Hydrochloric acid Solvents: 1,4-Dioxane ; 1 h, 27 °C; 10 min, 27 °C
1.2 Reagents: Triethylamine , Hydrochloric acid Solvents: Water ; basified

Reference

: Preparation of aminoquinoline derivatives for use as antimalarials

, India, , ,

Production Method 8

874-77-1

934-98-5

Reaction Conditions

1.1 Reagents: Lithium aluminum hydride Solvents: Diethyl ether

Reference

: Synthesis and cytotoxicity of novel indirubin-5-carboxamides

Cheng, Xinlai; Rasque, Paul; Vatter, Sandra; Merz, Karl-Heinz; Eisenbrand, Gerhard, Bioorganic & Medicinal Chemistry, 2010, 18(12), 4509-4515

Production Method 9

4489-39-8

934-98-5

Reaction Conditions

1.1 Reagents: Hydrazine hydrate (1:1) Solvents: Ethanol ; 24 h, reflux

Reference

: New pyrido[3,4-g]quinazoline derivatives as CLK1 and DYRK1A inhibitors: synthesis, biological evaluation and binding mode analysis

Tazarki, Helmi ; Zeinyeh, Wael; Esvan, Yannick J.; Knapp, Stefan; Chatterjee, Deep; et al, European Journal of Medicinal Chemistry, 2019, 166, 304-317

Production Method 10

4489-39-8

934-98-5

Reaction Conditions

1.1 Reagents: Hydrazine hydrate (1:1) Solvents: Ethanol ; 4 - 6 h, reflux

Reference

: Synthesis and antitumor activity of 5-bromo-7-azaindolin-2-one derivatives containing a 2,4-dimethyl-1H-pyrrole-3-carboxamide moiety

Zhang, Jun; Shen, Weiyi; Li, Xiaoning; Chai, Yun; Li, Senjun; et al, Molecules, 2016, 21(12), 1674-1683

Production Method 11

4489-39-8

934-98-5

Reaction Conditions

1.1 Reagents: Hydrazine hydrate (1:1) Solvents: Ethanol ; 24 h, rt → reflux

Reference

: Drug containing cinnamic acid amide, especially for chronic pain treatment

, Japan, , ,

Production Method 12

4489-39-8

934-98-5

Reaction Conditions

1.1 Reagents: Hydrazine hydrate (1:1) Solvents: Ethanol ; rt; 24 h, reflux

Reference

: Preparation of cinnamic acid amide derivatives as analgesics

, World Intellectual Property Organization, , ,

2-(4-methylpiperazin-1-yl)ethan-1-amine Raw materials

2-(4-methylpiperazin-1-yl)ethan-1-amine Preparation Products

2-(4-methylpiperazin-1-yl)ethan-1-amine (934-98-5)

2-(4-methylpiperazin-1-yl)ethan-1-amine Suppliers

Suzhou Senfeida Chemical Co., Ltd

Gold Member

Audited Supplier

(CAS:934-98-5)4-Methyl-1-piperazin

Order Number:1619449

Stock Status:in Stock

Quantity:Company Customization

Purity:98%

Pricing Information Last Updated:Monday, 14 April 2025 21:49

Price ($):discuss personally

Email:[email protected]

Amadis Chemical Company Limited

Gold Member

Audited Supplier

(CAS:934-98-5)2-(4-methylpiperazin-1-yl)ethan-1-amine

Order Number:A844616

Stock Status:in Stock

Quantity:5g/25g

Purity:99%

Pricing Information Last Updated:Friday, 30 August 2024 07:03

Price ($):219.0/877.0

Email:[email protected]

Product Official Link

Tiancheng Chemical (Jiangsu) Co., Ltd

Gold Member

Audited Supplier

(CAS:934-98-5)4-甲基-1-哌嗪乙胺

Order Number:LE1619449

Stock Status:in Stock

Quantity:25KG,200KG,1000KG

Purity:99%

Pricing Information Last Updated:Friday, 20 June 2025 12:29

Price ($):discuss personally

Email:[email protected]

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Related Categories

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Recommended suppliers

Suzhou Senfeida Chemical Co., Ltd

(CAS:934-98-5)4-Methyl-1-piperazin

Purity:98%

Quantity:Company Customization

Price ($):Inquiry

Amadis Chemical Company Limited

(CAS:934-98-5)2-(4-methylpiperazin-1-yl)ethan-1-amine

Purity:99%/99%

Quantity:5g/25g

Price ($):219.0/877.0

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Cas no 934-98-5 (2-(4-methylpiperazin-1-yl)ethan-1-amine)

2-(4-methylpiperazin-1-yl)ethan-1-amine Chemical and Physical Properties

Names and Identifiers

Computed Properties

Experimental Properties

2-(4-methylpiperazin-1-yl)ethan-1-amine Security Information

2-(4-methylpiperazin-1-yl)ethan-1-amine Customs Data

China Customs Code:

Overview:

Declaration elements:

Summary:

2-(4-methylpiperazin-1-yl)ethan-1-amine Pricemore >>

2-(4-methylpiperazin-1-yl)ethan-1-amine Production Method

Production Method 1

Production Method 2

Production Method 3

Production Method 4

Production Method 5

Production Method 6

Production Method 7

Production Method 8

Production Method 9

Production Method 10

Production Method 11

Production Method 12

2-(4-methylpiperazin-1-yl)ethan-1-amine Raw materials

2-(4-methylpiperazin-1-yl)ethan-1-amine Preparation Products

2-(4-methylpiperazin-1-yl)ethan-1-amine Suppliers

2-(4-methylpiperazin-1-yl)ethan-1-amine Related Literature

Related Categories

934-98-5 (2-(4-methylpiperazin-1-yl)ethan-1-amine) Related Products