Production Method 1

108-87-2

7443-55-2

96184-81-5

69814-26-2

7731-28-4

5454-79-5

7443-70-1

7443-52-9

2043-61-0

100-49-2

590-67-0

7731-29-5

1193-63-1

Reaction Conditions

1.1 Reagents: Hydrogen peroxide ,  Oxygen Catalysts: Nitric acid ,  Sodium, [μ13-[1,15-bis[[di(hydroxy-κO:κO)phenylsilyl]oxy-κO]-1,3,5,7,9,11,13,15-… Solvents: Acetonitrile

Reference

A heterometallic (Fe6Na8) cage-like silsesquioxane: synthesis, structure, spin glass behavior and high catalytic activity

Bilyachenko, Alexey N.; Levitsky, Mikhail M.; Yalymov, Alexey I.; Korlyukov, Alexander A.; Vologzhanina, Anna V.; et al, RSC Advances, 2016, 6(53), 48165-48180

trans-3-methylcyclohexan-1-ol Raw materials

• Methylcyclohexane

trans-3-methylcyclohexan-1-ol Preparation Products

• 4-Oxocyclohexanecarbaldehyde (96184-81-5)
• 3-oxocyclohexane-1-carbaldehyde (69814-26-2)
• cis-4-Methylcyclohexanol (7731-28-4)
• cis-3-methylcyclohexan-1-ol (5454-79-5)
• trans-3-methylcyclohexan-1-ol (7443-55-2)
• cis-2-Methylcyclohexanol (7443-70-1)
• trans-2-Methylcyclohexanol (7443-52-9)
• cyclohexanecarbaldehyde (2043-61-0)
• Cyclohexanemethanol (100-49-2)
• 1-Methylcyclohexanol (590-67-0)
• trans-4-Methylcyclohexanol (7731-29-5)
• 2-oxocyclohexanecarbaldehyde (1193-63-1)

• 1. Emulsion soft templating of carbide-derived carbon nanospheres with controllable porosity for capacitive electrochemical energy storage?
  M. Zeiger,N. J?ckel,P. Strubel,L. Borchardt,R. Reinhold,W. Nickel,J. Eckert,V. Presser,S. Kaskel J. Mater. Chem. A, 2015,3, 17983-17990
• 2. Emerging enantiomeric resolution materials with homochiral nano-fabrications
  Ji-Ping Wei Nanoscale, 2015,7, 11815-11832
• 3. Embedding cyclic nitrone in mesoporous silica particles for EPR spin trapping of superoxide and other radicals?
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• 4. Evolutionary de novo design of phenothiazine derivatives for dye-sensitized solar cells?
  Vishwesh Venkatraman,Marco Foscato,Vidar R. Jensen,Bj?rn K?re Alsberg J. Mater. Chem. A, 2015,3, 9851-9860
• 5. Enabling chloride salts for thermal energy storage: implications of salt purity?
  J. Matthew Kurley,Phillip W. Halstenberg,Abbey McAlister,Stephen Raiman,Richard T. Mayes RSC Adv., 2019,9, 25602-25608

• Solvents and Organic Chemicals Organic Compounds Organic oxygen compounds Organooxygen compounds Cyclohexanols

Trans-3-Methylcyclohexan-1-Ol: A Comprehensive Overview

Trans-3-methylcyclohexan-1-ol (CAS No. 7443-55-2) is an organic compound with a unique structural composition that has garnered significant attention in both academic and industrial research. This compound, also referred to as trans-cyclohexanol methyl derivative, belongs to the class of secondary alcohols and is characterized by its cyclohexane ring structure with a hydroxyl group (-OH) at the 1-position and a methyl group (-CH?) at the 3-position in a trans configuration. The trans stereochemistry plays a crucial role in determining its physical and chemical properties, making it a subject of interest in various fields such as organic synthesis, pharmacology, and materials science.

Recent advancements in analytical techniques have enabled researchers to delve deeper into the molecular properties of trans-3-methylcyclohexan-1-ol. For instance, studies utilizing nuclear magnetic resonance (NMR) spectroscopy have provided insights into its stereochemical arrangement, confirming the trans configuration through coupling constants analysis. Additionally, computational chemistry methods, such as density functional theory (DFT), have been employed to predict its electronic structure and reactivity under different conditions. These findings have not only enhanced our understanding of the compound's intrinsic properties but also paved the way for its application in diverse chemical processes.

The physical properties of trans-cyclohexanol methyl derivative are significantly influenced by its molecular geometry. It exhibits a melting point of approximately -60°C and a boiling point around 160°C, making it suitable for use in various thermal processes. The compound's solubility in organic solvents, particularly in non-polar solvents like hexane and dichloromethane, further highlights its versatility in different chemical environments. Recent research has also explored its behavior under extreme conditions, such as high-pressure environments, revealing potential applications in high-performance materials.

From a chemical standpoint, trans-cyclohexanol methyl derivative demonstrates moderate acidity due to the presence of the hydroxyl group, which can act as a proton donor under certain conditions. Its reactivity towards nucleophilic substitution reactions has been extensively studied, with findings indicating that it can undergo SN2 mechanisms under specific conditions. Furthermore, the compound's ability to form stable esters and ethers has made it a valuable precursor in organic synthesis pathways.

The applications of trans-cyclohexanol methyl derivative span across multiple industries. In the pharmaceutical sector, it serves as an intermediate in the synthesis of bioactive compounds with potential therapeutic applications. Recent studies have highlighted its role in drug design, where its stereochemical properties contribute to the development of enantiomerically pure compounds with enhanced pharmacokinetic profiles.

In the fragrance industry, trans-cyclohexanol methyl derivative is recognized for its pleasant odor profile, making it a popular ingredient in perfumes and personal care products. Its ability to impart floral and woody notes has positioned it as a key component in aromatic formulations.

From an environmental perspective, researchers have investigated the biodegradability of trans-cyclohexanol methyl derivative, concluding that it undergoes rapid degradation under aerobic conditions due to microbial activity. This characteristic aligns with current sustainability trends, emphasizing the importance of eco-friendly chemical compounds.

In conclusion, trans-cyclohexanol methyl derivative (CAS No. 7443-55-2) stands out as a multifaceted compound with promising applications across various domains. Its unique stereochemistry and versatile chemical properties continue to drive innovative research efforts aimed at unlocking its full potential.

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