Cas no 67815-54-7 (3,4,5-Trifluoropyridine)

3,4,5-Trifluoropyridine is a fluorinated pyridine derivative characterized by its trifluorinated aromatic ring structure. This compound is widely utilized as a versatile intermediate in pharmaceutical, agrochemical, and material science applications due to its electron-withdrawing properties and enhanced reactivity. The presence of three fluorine atoms at the 3, 4, and 5 positions imparts improved stability, lipophilicity, and metabolic resistance, making it valuable for designing bioactive molecules. Its high purity and consistent performance ensure reliable results in cross-coupling reactions, nucleophilic substitutions, and other synthetic transformations. The compound is typically supplied as a clear liquid or solid, with strict quality control to meet industry standards.
3,4,5-Trifluoropyridine structure
3,4,5-Trifluoropyridine structure
Product Name:3,4,5-Trifluoropyridine
CAS No:67815-54-7
MF:C5H2F3N
MW:133.071291446686
MDL:MFCD09998883
CID:58641
PubChem ID:16181465
Update Time:2025-10-13

3,4,5-Trifluoropyridine Chemical and Physical Properties

Names and Identifiers

    • 3,4,5-Trifluoropyridine
    • C5H2F3N
    • 3,4,5-Trifluor-pyridin
    • Pyridine,3,4,5-trifluoro
    • QC-7000
    • Pyridine, 3,4,5-trifluoro-
    • AK154261
    • 3,4,5-Trifluoro-pyridine
    • 3, 4, 5-trifluoropyridine
    • Pyridine,3,4,5-trifluoro-
    • OCKWONYIDVFISR-UHFFFAOYSA-N
    • BCP20087
    • BBL102207
    • STL556006
    • FCH880105
    • 7976AE
    • RP20038
    • PC51194
    • LS20926
    • AX8158095
    • AB0096829
    • TL80073986
    • 815T547
    • SB38272
    • CS-0223807
    • FT-0649375
    • 67815-54-7
    • C76146
    • DTXSID70583254
    • AMY12478
    • AKOS005063487
    • EN300-1167077
    • J-511111
    • SCHEMBL1643631
    • MFCD09998883
    • DS-7962
    • MDL： MFCD09998883
    • Inchi： 1S/C5H2F3N/c6-3-1-9-2-4(7)5(3)8/h1-2H
    • InChI Key： OCKWONYIDVFISR-UHFFFAOYSA-N
    • SMILES： FC1C(=CN=CC=1F)F

Computed Properties

  • Exact Mass: 133.01400
  • Monoisotopic Mass: 133.01393355g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 0
  • Hydrogen Bond Acceptor Count: 4
  • Heavy Atom Count: 9
  • Rotatable Bond Count: 0
  • Complexity: 88.2
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • Topological Polar Surface Area: 12.9
  • XLogP3: 1.2

Experimental Properties

  • PSA: 12.89000
  • LogP: 1.49890

3,4,5-Trifluoropyridine Security Information

  • HazardClass：IRRITANT

3,4,5-Trifluoropyridine Pricemore >>

Related Categories No. Product Name Cas No. Purity Specification Price update time Inquiry
SHANG HAI MAI KE LIN SHENG HUA Technology Co., Ltd.
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JIE DA WEI （ SHANG HAI ） YI YAO KE JI FA ZHAN Co., Ltd.
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JIE DA WEI （ SHANG HAI ） YI YAO KE JI FA ZHAN Co., Ltd.
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3,4,5-Trifluoro-pyridine
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Matrix Scientific
208532-1g
3,4,5-Trifluoropyridine, 97%
 67815-54-7 97%
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 $335.00 2023-09-07
Matrix Scientific
208532-5g
3,4,5-Trifluoropyridine, 97%
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SHANG HAI JI ZHI SHENG HUA Technology Co., Ltd.
T83180-25g
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3,4,5-Trifluoropyridine Production Method

Production Method 1

Reaction Conditions
1.1 Reagents: Triethylsilane Catalysts: (OC-6-43)-[1,3-Bis[2,6-bis(1-methylethyl)phenyl]-1,3-dihydro-2H-imidazol-2-ylide… Solvents: Tetrahydrofuran ;  19.45 h, 343 K
Reference
Catalytic Hydrodefluorination of Aromatic Fluorocarbons by Ruthenium N-Heterocyclic Carbene Complexes
Reade, Steven P.; et al, Journal of the American Chemical Society, 2009, 131(5), 1847-1861

3,4,5-Trifluoropyridine Raw materials

3,4,5-Trifluoropyridine Preparation Products

3,4,5-Trifluoropyridine Related Literature

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