Cas no 63223-86-9 (Ginsenoside Rh1)

Ginsenoside Rh1 is a bioactive saponin compound primarily derived from Panax ginseng, known for its potential pharmacological properties. As a protopanaxatriol-type ginsenoside, it exhibits notable anti-inflammatory, antioxidant, and immunomodulatory effects. Research suggests its role in modulating cellular signaling pathways, including NF-κB and MAPK, which may contribute to its therapeutic applications. Ginsenoside Rh1 has also demonstrated potential in enhancing skin health by promoting collagen synthesis and reducing oxidative stress. Its high purity and standardized composition make it suitable for research in nutraceuticals, cosmetics, and pharmaceuticals. The compound's stability and well-documented mechanisms of action further underscore its utility in scientific and industrial applications.
Ginsenoside Rh1 structure
Ginsenoside Rh1 structure
Product Name:Ginsenoside Rh1
CAS No:63223-86-9
MF:C36H62O9
MW:638.872092723846
MDL:MFCD09951797
CID:58011
PubChem ID:329758240
Update Time:2025-06-08

Ginsenoside Rh1 Chemical and Physical Properties

Names and Identifiers

    • Ginsenoside Rh1
    • (3beta,6alpha,12beta)-3,12,20-Trihydroxydammar-24-en-6-yl beta-D-glucopyranoside
    • Sanchinoside Rh1
    • GINSENOSIDE Rh1(AS) PrintBack
    • 20(s)-Ginsenoside Rh1
    • Ginsenoside-Rh1
    • Prosapogenin A2
    • Sanchinoside B2
    • (3β,6α,12β)-3,12,20-Trihydroxydammar-24-en-6-yl-β-D-glucopyranoside
    • (3beta,6alpha,12beta)-3,12,20-Trihydroxydammar-24-en-6-yl?beta-D-glucopyranoside
    • (2R,3R,4S,5S,6R)-2-[[(3S,6S,8R,9R,10R,12R,13R,17S)-3,12-Dihydroxy-17-[(2S)-2-hydroxy-6-methylhept-5-
    • HMS3886D18
    • ginsenoside G-Rh(1)
    • A834283
    • CHEBI:142487
    • BIDD:ER0183
    • (3beta,6alpha,12beta)-3,12,20-Trihydroxydammar-24-en-6-yl-beta-D-glucopyranoside
    • 20(S)?-?Ginsenoside Rh1
    • UNII-XBR6F7G8FU
    • (2R,3R,4S,5S,6R)-2-[[(3S,5R,6S,8R,10R,12R,14R,17S)-3,12-dihydroxy-17-[(2R)-2-hydroxy-6-methylhept-5-en-2-yl]-4,4,8,10,14-pentamethyl-2,3,5,6,7,9,11,12,13,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-6-yl]oxy]-6-(hydroxymethyl)oxane-3,4,5-triol
    • Ginsenoside Rh1, analytical standard
    • CHEMBL466844
    • S-GINSENOSIDE RH1
    • XBR6F7G8FU
    • (2R,3R,4S,5S,6R)-2-[[(3S,5R,6S,8R,9R,10R,12R,13R,14R,17S)-3,12-dihydroxy-17-[(2S)-2-hydroxy-6-methylhept-5-en-2-yl]-4,4,8,10,14-pentamethyl-2,3,5,6,7,9,11,12,13,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-6-yl]oxy]-6-(hydroxymethyl)oxane-3,4,5-triol
    • (20S)-ginsenoside Rh1
    • beta-D-Glucopyranoside, (3beta,6alpha,12beta)-3,12,20-trihydroxydammar-24-en-6-yl
    • s9129
    • AKOS025311542
    • 63223-86-9
    • (2R,3S,4S,5R,6R)-2-(hydroxymethyl)-6-[[(3S,5R,6S,8R,9R,10R,12R,13R,14R,17S)-4,4,8,10,14-pentamethyl-17-[(2S)-6-methyl-2-oxidanyl-hept-5-en-2-yl]-3,12-bis(oxidanyl)-2,3,5,6,7,9,11,12,13,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-6-yl]oxy]oxane-3,4,5-
    • C22129
    • DTXSID80979245
    • Prosapogenin A2; Sanchinoside B2; Sanchinoside Rh1
    • CCG-270315
    • .BETA.-D-GLUCOPYRANOSIDE, (3.BETA.,6.ALPHA.,12.BETA.)-3,12,20-TRIHYDROXYDAMMAR-24-EN-6-YL
    • Q-100729
    • AS-75346
    • HY-N0604
    • ginsenoside Rh(1)
    • MFCD09951797
    • GINSENOSIDE RH1, (20S)-
    • CS-3834
    • (2R,3R,4S,5S,6R)-2-{[(1S,3aR,3bR,5S,5aR,7S,9aR,9bR,11R,11aR)-7,11-dihydroxy-1-[(2S)-2-hydroxy-6-methylhept-5-en-2-yl]-3a,3b,6,6,9a-pentamethyl-hexadecahydro-1H-cyclopenta[a]phenanthren-5-yl]oxy}-6-(hydroxymethyl)oxane-3,4,5-triol
    • BDBM50023447
    • SY068757
    • 80952-71-2
    • SCHEMBL21297616
    • LS-15386
    • 2-[[3,12-Dihydroxy-17-(2-hydroxy-6-methylhept-5-en-2-yl)-4,4,8,10,14-pentamethyl-2,3,5,6,7,9,11,12,13,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-6-yl]oxy]-6-(hydroxymethyl)oxane-3,4,5-triol
    • (2R,3R,4S,5S,6R)-2-[[(3S,5R,6S,8R,9R,10R,12R,13R,14R,17S)-3,12-dihydroxy-17-[(2R)-2-hydroxy-6-methylhept-5-en-2-yl]-4,4,8,10,14-pentamethyl-2,3,5,6,7,9,11,12,13,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-6-yl]oxy]-6-(hydroxymethyl)oxane-3,4,5-triol
    • (20R)-Ginsenoside RH1
    • (S)-GINSENOSIDE RH1
    • DA-73730
    • (2R,3R,4S,5S,6R)-2-{[(1S,3AR,3BR,5S,5AR,7S,9AR,9BR,11R,11AR)-7,11-DIHYDROXY-1-[(2S)-2-HYDROXY-6-METHYLHEPT-5-EN-2-YL]-3A,3B,6,6,9A-PENTAMETHYL-DODECAHYDRO-1H-CYCLOPENTA[A]PHENANTHREN-5-YL]OXY}-6-(HYDROXYMETHYL)OXANE-3,4,5-TRIOL
    • MDL： MFCD09951797
    • Inchi： 1S/C36H62O9/c1-19(2)10-9-13-36(8,43)20-11-15-34(6)26(20)21(38)16-24-33(5)14-12-25(39)32(3,4)30(33)22(17-35(24,34)7)44-31-29(42)28(41)27(40)23(18-37)45-31/h10,20-31,37-43H,9,11-18H2,1-8H3/t20-,21+,22-,23+,24+,25-,26-,27+,28-,29+,30-,31+,33+,34+,35+,36-/m0/s1
    • InChI Key： RAQNTCRNSXYLAH-RFCGZQMISA-N
    • SMILES： O([C@H]1[C@@H]([C@H]([C@@H]([C@@H](CO)O1)O)O)O)[C@H]1C[C@]2(C)[C@H](C[C@H]([C@@H]3[C@@H]([C@](C)(CC/C=C(\C)/C)O)CC[C@@]23C)O)[C@@]2(C)CC[C@@H](C(C)(C)[C@@H]21)O

Computed Properties

  • Exact Mass: 638.43900
  • Monoisotopic Mass: 638.43938355 g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 7
  • Hydrogen Bond Acceptor Count: 9
  • Heavy Atom Count: 45
  • Rotatable Bond Count: 7
  • Complexity: 1110
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 14
  • Undefined Atom Stereocenter Count : 2
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • Molecular Weight: 638.9
  • Surface Charge: 0
  • XLogP3: 4.3
  • Topological Polar Surface Area: 160

Experimental Properties

  • Color/Form: Powder
  • Density: 1.23
  • Melting Point: No data available
  • Boiling Point: 755.079℃/760mmHg
  • Flash Point: 410.5±32.9 °C
  • Refractive Index: 1.581
  • PSA: 160.07000
  • LogP: 3.29560
  • Vapor Pressure: 0.0±5.7 mmHg at 25°C

Ginsenoside Rh1 Security Information

Ginsenoside Rh1 Pricemore >>

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Ginsenoside Rh1 Production Method

Production Method 1

Reaction Conditions
1.1 Solvents: Ethanol ,  Water ;  4 d, 26 °C
Reference
Microbial Transformation of 20(S)-Protopanaxatriol-Type Saponins by Absidia coerulea
Chen, Guangtong; et al, Journal of Natural Products, 2007, 70(7), 1203-1206

Production Method 2

Reaction Conditions
1.1 Solvents: Ethanol ,  Water ;  4 d, 26 °C
Reference
Microbial Transformation of 20(S)-Protopanaxatriol-Type Saponins by Absidia coerulea
Chen, Guangtong; Yang, Min; Lu, Zhiqiang; Zhang, Jinqiang; Huang, Huilian; et al, Journal of Natural Products, 2007, 70(7), 1203-1206

Production Method 3

Reaction Conditions
1.1 Reagents: Sodium Solvents: 1-Butanol
Reference
Alkaline cleavage of ginsenosides
Chen, Yingjie; et al, Chemical & Pharmaceutical Bulletin, 1987, 35(4), 1653-5

Production Method 4

Reaction Conditions
1.1 Catalysts: 12-Tungstosilicic acid Solvents: Methanol ,  Water ;  5 h, pH 3, rt → 60 °C
Reference
A novel catalytic application of heteropoly acids: Chemical transformation of major ginsenosides into rare ginsenosides exemplified by Rg1
Cao, Jie; et al, Science China: Chemistry, 2017, 60(6), 748-753

Production Method 5

Reaction Conditions
1.1 Solvents: Ethanol ,  Water ;  4 d, 26 °C
Reference
Microbial Transformation of 20(S)-Protopanaxatriol-Type Saponins by Absidia coerulea
Chen, Guangtong; et al, Journal of Natural Products, 2007, 70(7), 1203-1206

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Hubei Cuiyuan Biotechnology Co.,Ltd
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(CAS:63223-86-9)GinsenosideRh1
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Amadis Chemical Company Limited
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(CAS:63223-86-9)Ginsenoside Rh1
Order Number:A834283
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Purity:99%
Pricing Information Last Updated:Monday, 2 September 2024 15:37
Price ($):217.0
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(CAS:63223-86-9)Ginsenoside Rh1
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Quantity:25KG,200KG,1000KG
Purity:99%
Pricing Information Last Updated:Friday, 20 June 2025 12:02
Price ($):discuss personally

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Hubei Cuiyuan Biotechnology Co.,Ltd
(CAS:63223-86-9)GinsenosideRh1
CRN0071
Purity:≥98%
Quantity:5mg/20mg/50mg
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Amadis Chemical Company Limited
(CAS:63223-86-9)Ginsenoside Rh1
A834283
Purity:99%
Quantity:250mg
Price ($):217.0
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