Production Method 1

22427-39-0

364779-15-7

63223-86-9

53963-43-2

80952-73-4

2319608-29-0

340270-88-4

80952-71-2

Reaction Conditions

1.1 Catalysts: 12-Tungstosilicic acid Solvents: Methanol ,  Water ;  5 h, pH 3, rt → 60 °C

Reference

A novel catalytic application of heteropoly acids: Chemical transformation of major ginsenosides into rare ginsenosides exemplified by Rg1

Cao, Jie; et al, Science China: Chemistry, 2017, 60(6), 748-753

Ginsenoside Rk3 Raw materials

• Ginsenoside RG1

Ginsenoside Rk3 Preparation Products

• Ginsenoside Rh1 (63223-86-9)
• Ginsenoside Rk3 (364779-15-7)
• Ginsenoside F1 (53963-43-2)
• beta-D-Glucopyranoside, (3beta,6alpha,12beta,20R)-3,12,20,25-tetrahydroxydammaran-6-yl (80952-73-4)
• Dammar-24-ene-3,6,12,20-tetrol; (3β,6α,12β,20R)-form, 20-Me ether, 6-O-β-D-glucopyranoside (2319608-29-0)
• ginsenoside Rh5 (340270-88-4)
• (20R)-Ginsenoside Rh1 (80952-71-2)

• 1. An autoreduction method to prepare plasmonic gold-embedded polypeptide micelles for synergistic chemo-photothermal therapy?
  Xingjie Wu,Linzhu Zhou,Yue Su,Chang-Ming Dong J. Mater. Chem. B, 2016,4, 2142-2152
• 2. Acenaphthenic hopanoids, a novel series of aromatised
  Teresita Carrillo-Hernández,Philippe Schaeffer,Pierre Albrecht Chem. Commun., 2001, 1976-1977
• 3. An aptasensor for detection of potassium ions based on RecJf exonuclease mediated signal amplification
  Bidou Wang,Xifeng Chen Analyst, 2014,139, 5695-5699
• 4. An approach to asymmetric synthesis of β-aryl alanines by Pd(0)-catalyzed cross-coupling and cyanate-to-isocyanate rearrangement?
  Piotr Szcze?niak,Sebastian Stecko RSC Adv., 2015,5, 30882-30888
• 5. Acetylcholinesterase amperometric detection system based on a cobalt(II) tetraphenylporphyrin-modified electrode
  Analyst, 1996,121, 1123-1126

• Solvents and Organic Chemicals Organic Compounds Lipids and lipid-like molecules Prenol lipids Triterpenoids
• Triterpenoids

Ginsenoside Rk3 (CAS No. 364779-15-7): A Comprehensive Guide to Its Properties and Applications

Ginsenoside Rk3, with CAS number 364779-15-7, is a rare and highly bioactive compound derived from Panax ginseng. As one of the ginsenosides, it has gained significant attention in recent years due to its potential health benefits and therapeutic properties. This article delves into the chemical characteristics, pharmacological effects, and modern applications of Ginsenoside Rk3, while addressing common questions and trending topics in the field.

The molecular structure of Ginsenoside Rk3 belongs to the protopanaxadiol-type ginsenosides, characterized by its unique sugar moieties arrangement. With increasing interest in natural bioactive compounds and herbal medicine research, scientists have been exploring the mechanisms behind Ginsenoside Rk3's neuroprotective effects and anti-inflammatory properties. Recent studies published in journals like Phytomedicine and Journal of Ginseng Research highlight its potential in addressing modern health concerns.

One of the most searched topics regarding Ginsenoside Rk3 supplements relates to their potential role in cognitive health support. Current research suggests that this compound may help maintain brain function and protect against age-related cognitive decline, making it particularly relevant for aging populations. Another trending discussion point is its possible application in metabolic syndrome management, with preliminary studies indicating effects on glucose metabolism and lipid regulation.

The extraction and purification of Ginsenoside Rk3 (CAS 364779-15-7) typically involve advanced techniques such as high-performance liquid chromatography (HPLC) and preparative chromatography. These methods ensure high purity levels required for pharmaceutical research and nutraceutical applications. The compound's stability under various conditions has been extensively studied to optimize its formulation in dietary supplements and functional foods.

In the cosmetic industry, Ginsenoside Rk3 has emerged as a promising ingredient for anti-aging skincare products. Its potential to promote collagen synthesis and protect against oxidative stress aligns with the growing demand for natural anti-aging solutions. Formulators are particularly interested in its compatibility with other botanical extracts and its performance in various cosmetic delivery systems.

Quality control of Ginsenoside Rk3 raw material involves rigorous testing for identity, purity, and potency. Analytical methods such as LC-MS (Liquid Chromatography-Mass Spectrometry) are commonly employed to verify the compound's authenticity and quantify its concentration in finished products. These quality assurance measures are crucial for manufacturers developing standardized ginseng extracts and evidence-based herbal formulations.

The market for Ginsenoside Rk3 products has been expanding rapidly, driven by increasing consumer awareness of traditional medicine modernization and preventive healthcare approaches. Industry reports indicate growing demand in both North American markets and Asian markets, particularly among health-conscious consumers seeking natural alternatives to conventional therapies.

Recent advancements in biotechnological production of Ginsenoside Rk3 through plant cell culture and enzymatic biotransformation have addressed supply challenges associated with this rare compound. These innovative approaches not only improve yield but also enhance sustainability in the production of high-value ginsenosides, responding to environmental concerns in the botanical ingredient industry.

Safety evaluation studies have demonstrated favorable profiles for Ginsenoside Rk3 consumption within established dosage ranges. However, researchers emphasize the importance of clinical dose optimization and long-term safety assessment, especially for specific population groups. These considerations are particularly relevant for formulators developing targeted health products containing this bioactive compound.

Future research directions for Ginsenoside Rk3 (364779-15-7) include exploring its potential in personalized medicine applications and investigating synergistic effects with other phytochemical compounds. The scientific community is particularly interested in elucidating its molecular targets and signaling pathways, which could lead to novel therapeutic strategies for various health conditions.

For researchers and product developers seeking high-purity Ginsenoside Rk3, it's essential to source materials from reputable suppliers with comprehensive certificates of analysis and transparent manufacturing processes. Proper storage conditions, typically at controlled room temperature in protected from light containers, are crucial for maintaining the compound's stability and bioactivity over time.

The growing body of evidence supporting Ginsenoside Rk3 benefits continues to attract interest from both the scientific community and health-conscious consumers. As research progresses, this compound is poised to play an increasingly important role in integrative medicine approaches and preventive healthcare strategies, bridging traditional knowledge with modern scientific validation.

• 142735-55-5(b-D-Galactopyranoside, (1b,3b,16b,22S)-1-(b-D-glucopyranosyloxy)-3,22-dihydroxycholest-5-en-16-yl(9CI))
• 147419-93-0(Ginsenoside Rg6)
• 139975-46-5(b-D-Galactopyranoside, (1b,3b,16b,22S)-1-[(6-deoxy-a-L-mannopyranosyl)oxy]-3,22-dihydroxycholest-5-en-16-yl 3-O-(6-deoxy-a-L-mannopyranosyl)- (9CI))
• 100187-68-6(b-D-Glucopyranoside, (3b,6b)-5,6,16-trihydroxygrayanotox-9-en-3-yl (9CI))
• 142735-53-3(b-D-Galactopyranoside, (1b,3b,16b,22S)-1,3,22-trihydroxycholest-5-en-16-yl (9CI))
• 105558-26-7(Ginsenoside Rh3)
• 139953-18-7(b-D-Galactopyranoside, (3b,16b,22S)-3,22-dihydroxycholest-5-en-16-yl 3-O-(6-deoxy-a-L-mannopyranosyl)-)
• 139953-19-8(Cholest-5-ene-3,16,22-triol; (3β,16β,22S)-form, 3-O-β-D-Glucopyranoside, 16-O-[α-L-rhamnopyranosyl-(1→3)-β-D-galactopyranoside])
• 126223-28-7(Ginsenoside Rg4)
• 186763-78-0(Ginsenoside Rg5)