Cas no 252049-05-1 (Fmoc-menva-oh)

Fmoc-MenVA-OH is a protected amino acid derivative used in solid-phase peptide synthesis (SPPS). The Fmoc (9-fluorenylmethoxycarbonyl) group serves as a temporary protecting group for the amine functionality, enabling selective deprotection under mild basic conditions. The MenVA (methylnorvaline) side chain introduces structural modifications to peptides, enhancing stability or altering conformational properties. This compound is particularly valuable in designing peptide analogs with improved pharmacokinetic or binding characteristics. Its high purity and compatibility with standard SPPS protocols ensure reliable incorporation into peptide sequences. Fmoc-MenVA-OH is suitable for research applications requiring tailored peptide architectures, such as drug development or biochemical studies. Proper handling under anhydrous conditions is recommended to maintain integrity.
Fmoc-menva-oh structure
Fmoc-menva-oh structure
Product Name:Fmoc-menva-oh
CAS No:252049-05-1
MF:C21H23NO4
MW:353.41162610054
MDL:MFCD01861326
CID:246476
PubChem ID:354334626
Update Time:2025-06-08

Fmoc-menva-oh Chemical and Physical Properties

Names and Identifiers

    • L-Norvaline,N-[(9H-fluoren-9-ylmethoxy)carbonyl]-N-methyl-
    • N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-N-methyl-L-norvaline
    • (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)(methyl)amino)pentanoic acid
    • (2S)-2-[9H-fluoren-9-ylmethoxycarbonyl(methyl)amino]pentanoic acid
    • Fmoc-Nalpha-methyl-L-norvaline
    • Fmoc-N-Me-L-norvaline
    • Fmoc-N-Me-Nva-OH
    • FMOC-NΑ-METHYL-L-NORVALINE
    • (2S)-2-{[(9H-fluoren-9-ylmethoxy)carbonyl](methyl)amino}pentanoic acid
    • <i>N<
    • Fmoc-N-methyl-L-norvaline
    • L-Norvaline,N-[(9H-fluoren-9-ylmethoxy)carbonyl]-N-methyl
    • TMA050
    • N-Fmoc-N-methyl-L-norvaline
    • FMOC-MENVA-OH
    • F1166
    • A877665
    • 252049-05-1
    • (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)(methyl)amino)pentanoicacid
    • MFCD01861326
    • N-alpha-(9-Fluorenylmethyloxycarbonyl)-N-alpha-methyl-L-norvaline
    • DS-9027
    • CS-0089871
    • SCHEMBL120597
    • DTXSID20426586
    • Fmoc-Me-Nva-OH
    • (2S)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}(methyl)amino)pentanoic acid
    • AKOS015837160
    • EN300-321373
    • fmoc-menva-oh, AldrichCPR
    • Fmoc-N-Me-L-2-aminovaleric acid
    • L-Norvaline, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-N-methyl-
    • Fmoc-menva-oh
    • MDL: MFCD01861326
    • Inchi: 1S/C21H23NO4/c1-3-8-19(20(23)24)22(2)21(25)26-13-18-16-11-6-4-9-14(16)15-10-5-7-12-17(15)18/h4-7,9-12,18-19H,3,8,13H2,1-2H3,(H,23,24)/t19-/m0/s1
    • InChI Key: HKELUUGCKFRJQM-IBGZPJMESA-N
    • SMILES: O(C(N(C)[C@H](C(=O)O)CCC)=O)CC1C2C=CC=CC=2C2C=CC=CC1=2

Computed Properties

  • Exact Mass: 353.16300
  • Monoisotopic Mass: 353.16270821g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 1
  • Hydrogen Bond Acceptor Count: 5
  • Heavy Atom Count: 26
  • Rotatable Bond Count: 8
  • Complexity: 486
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 1
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • XLogP3: 4.1
  • Topological Polar Surface Area: 66.8?2

Experimental Properties

  • Density: 1.215±0.06 g/cm3 (20 oC 760 Torr),
  • Melting Point: 130.0 to 135.0 deg-C
  • Solubility: Almost insoluble (0.011 g/l) (25 o C),
  • PSA: 66.84000
  • LogP: 4.12060

Fmoc-menva-oh Security Information

  • HazardClass:IRRITANT
  • Storage Condition:Store in cold storage.

Fmoc-menva-oh Customs Data

  • HS CODE:2924299090
  • Customs Data:

    China Customs Code:

    2924299090

    Overview:

    2924299090. Other cyclic amides(Including cyclic carbamates)(Including their derivatives as well as their salts). VAT:17.0%. Tax refund rate:13.0%. Regulatory conditions:nothing. MFN tariff:6.5%. general tariff:30.0%

    Declaration elements:

    Product Name, component content, use to, packing

    Summary:

    2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

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Fmoc-menva-oh Suppliers

Suzhou Senfeida Chemical Co., Ltd
Gold Member
Audited Supplier Audited Supplier
(CAS:252049-05-1)FMOC-MENVA-OH
Order Number:sfd13514
Stock Status:in Stock
Quantity:200kg
Purity:99.9%
Pricing Information Last Updated:Friday, 19 July 2024 14:36
Price ($):discuss personally

Additional information on Fmoc-menva-oh

Comprehensive Overview of Fmoc-Menva-OH (CAS No. 252049-05-1): Properties, Applications, and Industry Trends

Fmoc-Menva-OH (CAS No. 252049-05-1) is a specialized Fmoc-protected amino acid derivative widely utilized in peptide synthesis and pharmaceutical research. This compound, featuring a 9-fluorenylmethoxycarbonyl (Fmoc) protecting group, is critical for solid-phase peptide synthesis (SPPS) due to its stability and selective deprotection properties. With the growing demand for peptide-based therapeutics and bioconjugation techniques, Fmoc-Menva-OH has garnered significant attention in both academic and industrial settings.

The molecular structure of Fmoc-Menva-OH includes a unique side chain that enhances its utility in designing peptide drugs and biomaterials. Researchers prioritize this compound for its compatibility with automated synthesizers and its role in producing high-purity peptides. Recent advancements in cancer research and targeted drug delivery systems have further highlighted the importance of Fmoc-protected building blocks like Fmoc-Menva-OH.

In the context of green chemistry and sustainable practices, Fmoc-Menva-OH aligns with the industry's shift toward eco-friendly solvents and reduced waste generation. Its applications extend to nanotechnology, where it serves as a linker for biofunctionalized surfaces. The compound's stability under mild conditions makes it ideal for click chemistry and other modern synthetic strategies.

From an SEO perspective, common queries such as "Fmoc-Menva-OH solubility", "CAS 252049-05-1 suppliers", and "Fmoc amino acid applications" reflect user interest in practical usage and sourcing. This article addresses these topics while emphasizing the compound's role in COVID-19-related peptide research and personalized medicine, two high-traffic areas in current scientific discourse.

Quality control of Fmoc-Menva-OH involves rigorous HPLC and MS analysis to ensure batch-to-batch consistency, a key concern for manufacturers. The compound's shelf life and storage conditions (typically 2–8°C under inert gas) are frequently searched, underscoring the need for precise handling protocols. Regulatory compliance, including REACH and FDA guidelines, further elevates its relevance in global markets.

Emerging trends like AI-driven peptide design and high-throughput screening have increased demand for reliable Fmoc reagents. As the pharmaceutical industry explores oral peptide delivery and multifunctional conjugates, Fmoc-Menva-OH remains a cornerstone for innovation. Its compatibility with microwave-assisted synthesis also positions it favorably for cutting-edge methodologies.

In summary, Fmoc-Menva-OH (CAS No. 252049-05-1) exemplifies the intersection of traditional peptide chemistry and modern therapeutic development. By addressing search intent around synthetic protocols, scaling challenges, and emerging applications, this overview bridges technical depth with real-world usability—optimizing both scientific value and online discoverability.

Recommended suppliers
Suzhou Senfeida Chemical Co., Ltd
(CAS:252049-05-1)FMOC-MENVA-OH
sfd13514
Purity:99.9%
Quantity:200kg
Price ($):Inquiry
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