Cas no 88050-17-3 ((2S,4R)-1-{[(9H-fluoren-9-yl)methoxy]carbonyl}-4-hydroxypyrrolidine-2-carboxylic acid)

(2S,4R)-1-{[(9H-fluoren-9-yl)methoxy]carbonyl}-4-hydroxypyrrolidine-2-carboxylic acid structure
88050-17-3 structure
Product Name:(2S,4R)-1-{[(9H-fluoren-9-yl)methoxy]carbonyl}-4-hydroxypyrrolidine-2-carboxylic acid
CAS No:88050-17-3
MF:C20H19NO5
MW:353.368565797806
MDL:MFCD00151929
CID:61137
PubChem ID:2756109
Update Time:2024-10-26

(2S,4R)-1-{[(9H-fluoren-9-yl)methoxy]carbonyl}-4-hydroxypyrrolidine-2-carboxylic acid Chemical and Physical Properties

Names and Identifiers

    • N-Fmoc-trans-4-hydroxy-L-proline
    • Fmoc-Hyp-OH
    • Fmoc-L-4-hydroxyproline
    • trans-N-Fmoc-4-hydroxy-L-proline
    • (2S,4R)-1-(((9H-Fluoren-9-yl)methoxy)carbonyl)-4-hydroxypyrrolidine-2-carboxylic acid
    • (2S,4R)-1-(9H-fluoren-9-ylmethoxycarbonyl)-4-hydroxypyrrolidine-2-carboxylic acid
    • Fmoc-(2S,4R)-(-)-4-hydroxypyrrolidine-2-carboxylic acid
    • Fmoc-L-Hydroxyproline
    • Fmoc-L-Hyp-OH
    • Fmoc-O-Hyp-OH
    • trans-1-(((9H-Fluoren-9-yl)methoxy)carbonyl)-4-hydroxypyrrolidine-2-carboxylic acid
    • FMoc-trans-4-hydroxy-L-proline
    • Fmoc-Hyp
    • Fmoc-trans-Hyp-OH
    • PubChem10495
    • KSC496S2P
    • N-alpha-(9-Fluorenylmethyloxycarbonyl)-trans-L-hydroxyproline
    • GOUUPUICWUFXPM-XIKOKIGWSA-N
    • Fmoc-trans-4-hydroxy-(L)-proline
    • RARECHEM EM WB 0137
    • N-FMOC-L-TRANS-4-HYDROXYPROLINE
    • N-ALPHA-FMOC-L-TRANS-4-HYDROXYPROLINE
    • trans-N-Fmoc-L-4-hydroxyproline
    • (2S,4R)-1-{[(9H-fluoren-9-yl)methoxy]carbonyl}-4-hydroxypyrrolidine-2-carboxylic acid
    • 1,2-Pyrrolidinedicarboxylic acid, 4-hydroxy-, 1-(9H-fluoren-9-ylmethyl) ester, (2S-trans)- (ZCI)
    • 231: PN: US20070042401 PAGE: 33 claimed protein
    • N-(9-Fluorenylmethyloxycarbonyl)-trans-4-hydroxy-L-proline
    • AC-24038
    • SCHEMBL119261
    • Fmoc-Hyp-OH, >=98.0% (sum of enantiomers, HPLC)
    • J-300153
    • Z1160837640
    • 98%(sum of enantiomers)
    • DTXSID60373242
    • FD21755
    • M03165
    • EN300-20812961
    • DS-13399
    • AKOS015922830
    • (2S, 4R)-1-[(9H-fluoren-9-ylmethoxy) carbonyl]-4-hydroxypyrrolidine-2-carboxylic acid
    • MFCD00151929
    • 88050-17-3
    • (2S,4R)-1-[(9H-fluoren-9-ylmethoxy)carbonyl]-4-hydroxypyrrolidine-2-carboxylic acid
    • HY-W008205
    • rac-(2R,4S)-1-{[(9H-fluoren-9-yl)methoxy]carbonyl}-4-hydroxypyrrolidine-2-carboxylic acid
    • (4R)-1-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-4-hydroxy-L-proline
    • CS-W008205
    • AKOS013155408
    • EN300-81273
    • MDL： MFCD00151929
    • Inchi： 1S/C20H19NO5/c22-12-9-18(19(23)24)21(10-12)20(25)26-11-17-15-7-3-1-5-13(15)14-6-2-4-8-16(14)17/h1-8,12,17-18,22H,9-11H2,(H,23,24)/t12-,18+/m1/s1
    • InChI Key： GOUUPUICWUFXPM-XIKOKIGWSA-N
    • SMILES： C(C1C2=CC=CC=C2C2C=CC=CC1=2)OC(N1C[C@H](O)C[C@H]1C(=O)O)=O

Computed Properties

  • Exact Mass: 353.12600
  • Monoisotopic Mass: 353.126
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 2
  • Hydrogen Bond Acceptor Count: 5
  • Heavy Atom Count: 26
  • Rotatable Bond Count: 4
  • Complexity: 530
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 2
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • Topological Polar Surface Area: 87.1
  • Surface Charge: 0
  • Tautomer Count: nothing
  • XLogP3: 2.4

Experimental Properties

  • Color/Form: White to off white crystalline powder
  • Density: 1.407
  • Melting Point: 189-193?°C
  • Boiling Point: 595.5℃ at 760 mmHg
  • Flash Point: 314°C
  • Refractive Index: 1.658
  • PSA: 87.07000
  • LogP: 2.39320
  • Optical Activity: [α]20/D ?60±2°, c =?1% in methanol

(2S,4R)-1-{[(9H-fluoren-9-yl)methoxy]carbonyl}-4-hydroxypyrrolidine-2-carboxylic acid Security Information

  • Signal Word：Warning
  • Hazard Statement： H315-H319-H335
  • Warning Statement： P261-P305+P351+P338
  • Hazardous Material transportation number：NONH for all modes of transport
  • WGK Germany：3
  • Safety Instruction： S22; S24/25
  • HazardClass：IRRITANT
  • Storage Condition：2-8°C

(2S,4R)-1-{[(9H-fluoren-9-yl)methoxy]carbonyl}-4-hydroxypyrrolidine-2-carboxylic acid Customs Data

  • HS CODE：2933990090
  • Customs Data：

    China Customs Code:

    2933990090

    Overview:

    2933990090. Other heterocyclic compounds containing only nitrogen heteroatoms. VAT:17.0%. Tax refund rate:13.0%. Regulatory conditions:nothing. MFN tariff:6.5%. general tariff:20.0%

    Declaration elements:

    Product Name, component content, use to, Please indicate the appearance of Urotropine, 6- caprolactam please indicate the appearance, Signing date

    Summary:

    2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

(2S,4R)-1-{[(9H-fluoren-9-yl)methoxy]carbonyl}-4-hydroxypyrrolidine-2-carboxylic acid Pricemore >>

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TRC
F633205-100mg
Fmoc-Hyp-OH
 88050-17-3
100mg
 $64.00 2023-05-18
TRC
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 88050-17-3
250mg
 $75.00 2023-05-18
TRC
F633205-500mg
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 $87.00 2023-05-18
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 $ 80.00 2022-06-04
SHANG HAI YI EN HUA XUE JI SHU Co., Ltd.
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(2S,4R)-1-{[(9H-fluoren-9-yl)methoxy]carbonyl}-4-hydroxypyrrolidine-2-carboxylic acid
 88050-17-3 97%
100g
 ￥418 2024-05-21
SHANG HAI YI EN HUA XUE JI SHU Co., Ltd.
R003951-25g
(2S,4R)-1-{[(9H-fluoren-9-yl)methoxy]carbonyl}-4-hydroxypyrrolidine-2-carboxylic acid
 88050-17-3 97%
25g
 ￥123 2024-05-21

(2S,4R)-1-{[(9H-fluoren-9-yl)methoxy]carbonyl}-4-hydroxypyrrolidine-2-carboxylic acid Production Method

Production Method 1

Reaction Conditions
1.1 Reagents: N-Methyl-N-(trimethylsilyl)trifluoroacetamide Solvents: Dichloromethane
1.2 Solvents: Dichloromethane
1.3 Reagents: Methanol
Reference
An efficient procedure for the preparation of Fmoc-amino acids
Raillard, Stephen P.; et al, Organic Preparations and Procedures International, 1998, 30(2), 183-186

(2S,4R)-1-{[(9H-fluoren-9-yl)methoxy]carbonyl}-4-hydroxypyrrolidine-2-carboxylic acid Raw materials

(2S,4R)-1-{[(9H-fluoren-9-yl)methoxy]carbonyl}-4-hydroxypyrrolidine-2-carboxylic acid Preparation Products

(2S,4R)-1-{[(9H-fluoren-9-yl)methoxy]carbonyl}-4-hydroxypyrrolidine-2-carboxylic acid Suppliers

Amadis Chemical Company Limited
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(CAS:88050-17-3)(2S,4R)-1-{[(9H-fluoren-9-yl)methoxy]carbonyl}-4-hydroxypyrrolidine-2-carboxylic acid
Order Number:A10478
Stock Status:in Stock
Quantity:500g
Purity:99%
Pricing Information Last Updated:Thursday, 29 August 2024 17:25
Price ($):269.0
Suzhou Senfeida Chemical Co., Ltd
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(CAS:88050-17-3)Fmoc-L-hydroxyproline
Order Number:sfd11533
Stock Status:in Stock
Quantity:200kg
Purity:99.9%
Pricing Information Last Updated:Friday, 19 July 2024 14:35
Price ($):discuss personally
Tiancheng Chemical (Jiangsu) Co., Ltd
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(CAS:88050-17-3)Fmoc-L-羥脯氨酸
Order Number:LE25956586
Stock Status:in Stock
Quantity:25KG,200KG,1000KG
Purity:99%
Pricing Information Last Updated:Friday, 20 June 2025 12:54
Price ($):discuss personally

(2S,4R)-1-{[(9H-fluoren-9-yl)methoxy]carbonyl}-4-hydroxypyrrolidine-2-carboxylic acid Related Literature

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88050-17-3 ((2S,4R)-1-{[(9H-fluoren-9-yl)methoxy]carbonyl}-4-hydroxypyrrolidine-2-carboxylic acid) Related Products

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Amadis Chemical Company Limited
(CAS:88050-17-3)(2S,4R)-1-{[(9H-fluoren-9-yl)methoxy]carbonyl}-4-hydroxypyrrolidine-2-carboxylic acid
A10478
Purity:99%
Quantity:500g
Price ($):269.0
Email
Suzhou Senfeida Chemical Co., Ltd
(CAS:88050-17-3)Fmoc-L-hydroxyproline
sfd11533
Purity:99.9%
Quantity:200kg
Price ($):Inquiry
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