Cas no 20762-30-5 (ADP Ribose)

ADP Ribose structure
ADP Ribose structure
Product Name:ADP Ribose
CAS No:20762-30-5
MF:C15H23N5O14P2
MW:559.315745592117
CID:910484
PubChem ID:30243
Update Time:2025-04-19

ADP Ribose Chemical and Physical Properties

Names and Identifiers

    • [5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl [hydroxy-[(3,4,5-trihydroxyoxolan-2-yl)methoxy]phosphoryl] hydrogen phosphate
    • adenosine 5'-diphosphoribose
    • Adenosine diphosphate ribose
    • Adenosine pyrophosphate-ribose
    • ADPR
    • diphosphoric acid-1-adenosin-5'-yl ester-2-D-ribose-5-yl ester
    • Diphosphorsaeure-1-adenosin-5'-ylester-2-D-ribose-5-ylester
    • Ribose adenosinediphosphate
    • Ribose adenosinediphosphate
    • Adenosine pyrophosphate-ribose
    • Adenosine diphosphoribose
    • Adenosine diphosphate ribose
    • Adenosine 5'-diphosphoribose
    • Adenosine 5'-(trihydrogen diphosphate), P'→5-ester with D- ribofuranose
    • ADPR (nucleotide)
    • ADPR
    • ADP ribose
    • 5-(Adenosine 5'-pyrophosphoryl)-D-ribose
    • Ribofuranose, 5→5'-ester with adenosine 5'-(trihydrogen pyrophosphate), D- (8CI)
    • Adenosine 5'-pyrophosphate, 5'→5-ester with D-ribofuranose (7CI)
    • Adenosine 5'-diphosphate, D-ribose ester (6CI)
    • Adenosine 5'-(trihydrogen pyrophosphate), 5'→5-ester with D-ribofuranose (8CI)
    • Adenosine 5'-(trihydrogen diphosphate), P'→5-ester with D-ribose
    • UNII-XV3S4KV26E
    • Adenosine 5'-diphosphate, D-ribose ester (6CI)
    • Adenosine 5'-(trihydrogen diphosphate), P'-->5-ester with D-ribose
    • GTPL2444
    • Adenosine 5'-(trihydrogen diphosphate), P'-5-ester with D-ribose (9CI)
    • ADP Ribose
    • Ribofuranose, 5-5'-ester with adenosine 5'-(trihydrogen pyrophosphate), D-
    • ADPR (nucleotide)
    • D0E9LJ
    • Adenosine 5'-(trihydrogen pyrophosphate), 5'-5-ester with D-ribofuranose (8CI)
    • Q27074316
    • [32P]-ADP-ribose
    • Adenosine 5'-(trihydrogen pyrophosphate), 5'-5-ester with D-ribofuranose
    • Adenosine 5'-pyrophosphate, 5'-5-ester with D-ribofuranose (7CI)
    • 20762-30-5
    • [(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl [hydroxy-[(2R,3R,4R)-2,3,4-trihydroxy-5-oxopentoxy]phosphoryl] hydrogen phosphate
    • JNT
    • Ribofuranose, 5-5'-ester with adenosine 5'-(trihydrogen pyrophosphate), D- (8CI)
    • Adenosine diphosphoribose
    • Adenosine 5'-diphosphate, D-ribose ester
    • XV3S4KV26E
    • Adenosine 5'-pyrophosphate, 5'→5-ester with D-ribofuranose (7CI)
    • Ribofuranose, 5→5'-ester with adenosine 5'-(trihydrogen pyrophosphate), D- (8CI)
    • 5-(Adenosine 5'-pyrophosphoryl)-D-ribose
    • Adenosine 5'-(trihydrogen diphosphate), P'→5-ester with D-ribofuranose
    • Adenosine 5'-diphosphoric acid β-(5-deoxy-D-ribos-5-yl) ester
    • Adenosindiphosphoribose
    • (((2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl)methoxy-hydroxyphosphoryl) ((2R,3R,4R)-2,3,4-trihydroxy-5-oxopentyl) hydrogen phosphate
    • [[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] [(2R,3R,4R)-2,3,4-trihydroxy-5-oxopentyl] hydrogen phosphate
    • 1ST161970
    • ((2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl)methyl (hydroxy-((2R,3R,4R)-2,3,4-trihydroxy-5-oxopentoxy)phosphoryl) hydrogen phosphate
    • Inchi: 1S/C15H23N5O14P2/c16-13-9-14(18-4-17-13)20(5-19-9)15-12(26)11(25)8(33-15)3-32-36(29,30)34-35(27,28)31-2-7(23)10(24)6(22)1-21/h1,4-8,10-12,15,22-26H,2-3H2,(H,27,28)(H,29,30)(H2,16,17,18)/t6-,7+,8+,10-,11+,12+,15+/m0/s1
    • InChI Key: PWJFNRJRHXWEPT-AOOZFPJJSA-N
    • SMILES: P(=O)(O)(OP(=O)(O)OC[C@H]([C@H]([C@H](C=O)O)O)O)OC[C@@H]1[C@H]([C@H]([C@H](N2C=NC3C(N)=NC=NC2=3)O1)O)O

Computed Properties

  • Exact Mass: 591.06200
  • Monoisotopic Mass: 559.07167442g/mol
  • Isotope Atom Count: 0
  • Hydrogen Bond Donor Count: 8
  • Hydrogen Bond Acceptor Count: 18
  • Heavy Atom Count: 36
  • Rotatable Bond Count: 12
  • Complexity: 860
  • Covalently-Bonded Unit Count: 1
  • Defined Atom Stereocenter Count: 7
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • XLogP3: -6.4
  • Topological Polar Surface Area: 299?2

Experimental Properties

  • Density: 2.24±0.1 g/cm3(Predicted)
  • Boiling Point: 1007.5±75.0 °C(Predicted)
  • PSA: 340.60000
  • LogP: -3.45150
  • pka: 1.13±0.50(Predicted)

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ADP Ribose Production Method

Production Method 1

Reaction Conditions
1.1R:2-PySSPy-2, R:Et3N, R:PPh3, S:DMF, 6-8 h, rt
1.2R:NaClO4, S:Me2CO, rt
2.1R:MgCl2, S:DMF, 5 min, rt
2.2S:DMF, 8 h, rt
2.3R:H2O
Reference
Efficient and Rapid Synthesis of Nucleoside Diphosphate Sugars from Nucleoside Phosphorimidazolides
By Dabrowski-Tumanski, Pawel et al, European Journal of Organic Chemistry, 2013, 2013(11), 2147-2154

Production Method 2

Reaction Conditions
1.1
Reference
Putative chanzyme activity of TRPM2 cation channel is unrelated to pore gating
By Toth, Balazs et al, Proceedings of the National Academy of Sciences of the United States of America, 2014, 111(47), 16949-16954

Production Method 3

Reaction Conditions
1.1R:C5H5N, rt
1.220 min, 90°C
1.3S:MeOH, S:EtOH, S:Me2CHOH, 90°C → rt
Reference
One-Step, Non-Enzymatic Synthesis of O-Acetyl-ADP-ribose and Analogs from NAD and Carboxylates
By Szczepankiewicz, Bruce G. et al, Journal of Organic Chemistry, 2011, 76(16), 6465-6474

Production Method 4

Reaction Conditions
1.1S:H2O, 16 h, 50°C
2.1S:H2O, 16 h, 50°C
Reference
Factors influencing the operational stability of NADPH-dependent alcohol dehydrogenase and an NADH-dependent variant thereof in gas/solid reactors
By Kulishova, Liliya et al, Journal of Molecular Catalysis B: Enzymatic, 2010, 67(3-4), 271-283

ADP Ribose Raw materials

ADP Ribose Preparation Products

ADP Ribose Suppliers

NewCan Biotech Limited
Gold Member
Audited Supplier Audited Supplier
(CAS:20762-30-5)Adenosindiphosphoribose
Order Number:NC25560
Stock Status:
Quantity:10g
Purity:97%
Pricing Information Last Updated:Friday, 18 July 2025 16:09
Price ($):Price inquiry
Recommended suppliers
NewCan Biotech Limited
(CAS:20762-30-5)Adenosindiphosphoribose
NC25560
Purity:97%
Quantity:10g
Price ($):Inquiry
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