Purine ribonucleoside diphosphates
Purine ribonucleoside diphosphates are essential intermediates in the biosynthesis of RNA and DNA. These compounds, composed of purine bases (adenosine or guanosine) linked to two phosphate groups, play a critical role in cellular metabolism by providing the necessary building blocks for nucleic acid synthesis. They serve as substrates for various enzymes involved in nucleotide metabolism, including kinases and nucleotidyltransferases. The stability and purity of purine ribonucleoside diphosphates are crucial for maintaining accurate biochemical reactions and ensuring reliable research outcomes. These compounds are commonly used in molecular biology laboratories for the study of RNA synthesis, gene expression analysis, and enzyme kinetics assays.
| Structure | Chemical Name | CAS | MF |
|---|---|---|---|
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Adenosine 5'-(trihydrogen diphosphate), 2-(methylthio)- | 34983-48-7 | C11H17N5O10P2S |
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Adenosine 5'-(trihydrogen diphosphate), P'-anhydride with phosphorothioic acid | 35094-46-3 | C10H16N5O12P3S |
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Coenzyme A, 3'-O-dephosphono- | 3633-59-8 | C21H35N7O13P2S |
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Inosine 5'-(Trihydrogen Diphosphate) Monohydrate Trisodium Salt | 81012-88-6 | C10H16N4NaO12P2 |
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(IDP) Inosine 5'-diphosphate disodium salt | 86-04-4 | C10H14N4O11P2 |
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Guanosine 5'-Diphosphate Disodium Salt (>85%) | 7415-69-2 | C10H13N5Na2O11P2 |
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Adenosine 5'-Diphosphate Sodium Salt | 20398-34-9 | C10H12N5Na3O10P2 |
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Adenosine 5′-Diphosphate bis(Cyclohexylammonium) Salt | 102029-87-8 | C22H41N7O10P2 |
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Guanosine 5'-diphosphate tris salt | 103192-39-8 | C14H26N6O14P2 |
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Adenosine 5'-(trihydrogen diphosphate), P'→5'-ester with 3-iodo-1-β-D-ribofuranosylpyridinium, inner salt (9CI) | 56541-70-9 | C20H25IN6O13P2 |
Related Literature
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Matthew J. Gaunt,Jinquan Yu,Jonathan B. Spencer Chem. Commun., 2001, 1844-1845
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Christopher B. Rodell,Christopher B. Highley,Minna H. Chen,Neville N. Dusaj,Chao Wang,Lin Han,Jason A. Burdick Soft Matter, 2016,12, 7839-7847
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Domenico Lombardo,Gianmarco Munaò,Pietro Calandra,Luigi Pasqua,Maria Teresa Caccamo Phys. Chem. Chem. Phys., 2019,21, 11983-11991
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Gloria Belén Ramírez-Rodríguez,José Manuel Delgado-López,Jaime Gómez-Morales CrystEngComm, 2013,15, 2206-2212
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Olga Guselnikova,Gérard Audran,Jean-Patrick Joly,Andrii Trelin,Evgeny V. Tretyakov,Vaclav Svorcik,Oleksiy Lyutakov,Sylvain R. A. Marque Chem. Sci., 2021,12, 4154-4161
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