Cas no 20515-38-2 (Acetic-d3 acid,ammonium salt (8CI))
Acetic-d3 acid,ammonium salt (8CI) Chemical and Physical Properties
Names and Identifiers
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- Acetic-d3 acid,ammonium salt (8CI)
- azanium,2,2,2-trideuterioacetate
- Ammonium acetate-D3
- DE705A
- 20515-38-2
- azanium;2,2,2-trideuterioacetate
- Ammonium (~2~H_3_)acetate
- DTXSID70679843
-
- Inchi: 1S/C2H4O2.H3N/c1-2(3)4;/h1H3,(H,3,4);1H3/i1D3;
- InChI Key: USFZMSVCRYTOJT-NIIDSAIPSA-N
- SMILES: [O-]C(C([2H])([2H])[2H])=O.[NH4+]
Computed Properties
- Exact Mass: 80.06650
- Monoisotopic Mass: 80.066508704g/mol
- Isotope Atom Count: 3
- Hydrogen Bond Donor Count: 1
- Hydrogen Bond Acceptor Count: 2
- Heavy Atom Count: 5
- Rotatable Bond Count: 0
- Complexity: 25.5
- Covalently-Bonded Unit Count: 2
- Defined Atom Stereocenter Count: 0
- Undefined Atom Stereocenter Count : 0
- Defined Bond Stereocenter Count: 0
- Undefined Bond Stereocenter Count: 0
- Topological Polar Surface Area: 41.1?2
Experimental Properties
- Melting Point: 110-112?°C (dec.)(lit.)
- PSA: 40.13000
- LogP: -0.86760
Acetic-d3 acid,ammonium salt (8CI) Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| Apollo Scientific | DE705-1g |
Ammonium acetate-D3 >98 Atom % D |
20515-38-2 | >98 Atom % D | 1g |
£40.00 | 2022-04-28 | |
| Apollo Scientific | DE705A-5g |
Ammonium acetate-D3 >98 Atom % D |
20515-38-2 | >98 Atom % D | 5g |
£128.00 | 2022-04-28 | |
| Apollo Scientific | DE705A-5g |
Ammonium acetate-D3 5g bottle |
20515-38-2 | >98 Atom % D | 5g |
£128.00 | 2023-09-01 | |
| Apollo Scientific | DE705-1g |
Ammonium acetate-D3 1g bottle |
20515-38-2 | >98 Atom % D | 1g |
£40.00 | 2023-09-01 |
Acetic-d3 acid,ammonium salt (8CI) Related Literature
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1. An integrated microfluidic 3D tumor system for parallel and high-throughput chemotherapy evaluation?Dan Liu,Rui Hu,Zhongchao Huang,Meilin Sun,Kai Han Analyst, 2020,145, 6447-6455
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José M. Rivera,Mariana Martín-Hidalgo,Jean C. Rivera-Ríos Org. Biomol. Chem., 2012,10, 7562-7565
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Wenjie Zhao,Hua Hou,Yuchun Jin,Zhixiang Zeng,Xuedong Wu,Qunji Xue RSC Adv., 2014,4, 60307-60315
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Robert P. Davies,Maria A. Giménez,Laura Patel,Andrew J. P. White Dalton Trans., 2008, 5705-5707
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Michael Kappl,Paul M. Young,Daniela Traini,Sanyog Jain RSC Adv., 2016,6, 25789-25798
Additional information on Acetic-d3 acid,ammonium salt (8CI)
Professional Introduction to Acetic-d3 acid, ammonium salt (8CI) and CAS No. 20515-38-2
The compound CAS No. 20515-38-2, identified as Acetic-d3 acid, ammonium salt (8CI), represents a specialized derivative of acetic acid with deuterium-labeled carbon atoms. This compound has garnered significant attention in the field of chemical biology and pharmaceutical research due to its unique isotopic properties and potential applications in metabolic studies and drug development.
Acetic-d3 acid, ammonium salt (8CI) is a deuterated analog of acetic acid, where the hydrogen atoms at the carboxyl group are replaced by deuterium atoms. This modification enhances the compound's stability under various analytical conditions, making it an invaluable tool for NMR spectroscopy and mass spectrometry. The ammonium salt form improves solubility in polar solvents, facilitating its use in a wide range of biochemical assays.
In recent years, the demand for isotopically labeled compounds has surged, driven by advancements in analytical techniques and the need for precise metabolic studies. CAS No. 20515-38-2 fits into this trend by providing researchers with a reliable and high-purity source of deuterated acetic acid. This compound is particularly useful in tracing metabolic pathways and studying enzyme kinetics, where the incorporation of deuterium-labeled substrates can offer insights into reaction mechanisms and metabolic fluxes.
One of the most compelling applications of Acetic-d3 acid, ammonium salt (8CI) is in the field of drug discovery and development. Deuterated compounds have been shown to exhibit improved pharmacokinetic properties, including longer half-lives and reduced metabolism by certain enzymes. This has led to the exploration of deuterated analogs as prodrugs or as tools to study drug-drug interactions. For instance, studies have demonstrated that deuterated versions of small molecule drugs can exhibit altered metabolic clearance rates, providing valuable data for optimizing therapeutic regimens.
The use of CAS No. 20515-38-2 in clinical research has also been explored for its potential role in diagnostic imaging. Deuterated compounds can be incorporated into tracers used in positron emission tomography (PET) scans, allowing researchers to visualize metabolic processes in vivo with high precision. This has opened up new avenues for studying diseases such as cancer, neurodegenerative disorders, and metabolic syndromes.
Furthermore, the chemical synthesis of Acetic-d3 acid, ammonium salt (8CI) has been refined over recent years to achieve higher yields and purities. Modern synthetic techniques, including catalytic hydrogenation and isotopic exchange reactions, have enabled the production of large quantities of this compound for industrial and research applications. These advancements have made it more accessible to scientists worldwide, fostering further innovation in chemical biology and pharmaceutical sciences.
The versatility of CAS No. 20515-38-2 extends beyond its use as a research tool; it also finds applications in quality control and method development within the pharmaceutical industry. Its distinct isotopic signature allows for easy detection and quantification using various analytical methods, ensuring compliance with regulatory standards and improving the accuracy of drug formulations.
In conclusion, Acetic-d3 acid, ammonium salt (8CI) represents a significant advancement in isotopically labeled compounds for scientific research. Its unique properties make it an indispensable tool for metabolic studies, drug development, and diagnostic imaging. As research continues to uncover new applications for deuterated compounds like CAS No. 20515-38-2, its importance in advancing our understanding of biological processes and developing novel therapeutics is set to grow even further.
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