- Carry Over of Impurities: A Detailed Exemplification for Glycopyrrolate (NVA237)Allmendinger, Thomas; Bixel, Dominique; Clarke, Adrian; Di Geronimo, Laura; Fredy, Jean-Wilfried; et al, Organic Process Research & Development, 2012, 16(11), 1754-1769
Cas no 13220-33-2 (1-Methyl-3-pyrrolidinol)
1-Methyl-3-pyrrolidinol is a versatile heterocyclic compound with a pyrrolidine backbone substituted by a hydroxyl group and a methyl group. This secondary alcohol exhibits favorable solubility in polar solvents, making it useful as an intermediate in organic synthesis and pharmaceutical applications. Its structural features enable participation in reactions such as alkylation, acylation, and reductive amination, facilitating the production of fine chemicals and active pharmaceutical ingredients (APIs). The compound's stability and moderate reactivity contribute to its utility in controlled synthetic processes. Additionally, its chiral center allows for potential use in stereoselective synthesis, enhancing its value in asymmetric catalysis and chiral auxiliary applications.
1-Methyl-3-pyrrolidinol structure
Product Name:1-Methyl-3-pyrrolidinol
CAS No:13220-33-2
MF:C5H11NO
MW:101.146941423416
MDL:MFCD00003176
CID:49110
PubChem ID:93074
Update Time:2025-05-28
1-Methyl-3-pyrrolidinol Chemical and Physical Properties
Names and Identifiers
-
- N-Methyl-3-pyrrolidinol
- N-METHYL 3-PYRROLIDINOL
- N-Methyl-3-Pyrrolidionol
- 1-Methylpyrrolidin-3-ol
- 1-Methyl-3-pyrrolidinol
- 1-Methyl-3-pyrrolidi
- 3-Hydroxy-1-methylpyrrolidine
- 1-methyl-3-hydroxypyrrolidine
- 1-METHYL-PYRROLIDIN-3-OL
- 3-Hydroxy-1-methylpyrroli...
- 3-hydroxy-N-methylpyrrolidine
- l-methyl-3-pyrrolidinol
- N-Methyl-3-hydroxy
- N-methyl-3-hydroxypyrrolidine
- N-Methyl-pyrrolidin-3-ol
- S(+)-1-methyl-3-pyrrolidinol
- NSC 89279
- N-Methyl-3-hydroxy-
- 3-Pyrrolidinol, 1-methyl-
- 1-Methyl-3-pyrrolidinol,97%
- (R)-3-Hydroxy-1-methylpyrrolidine
- (S)-3-Hydroxy-1-methylpyrrolidine
- NSC89279
- PubChem14117
- 1-methyl-pyrrolidin-3ol
- 3-Hydroxy-1-methylpyrroldine
- 99445-21-3
- SB10212
- CGW2AL7PQ7
- AS-11358
- 1-Methyl-3-pyrrolidinol, 95%
- EINECS 236-189-3
- CHEMBL4752499
- SY003953
- DTXSID10864377
- NSC-89279
- PENTAERYTHRITOLTETRA(MERCAPTOACETATE)
- 13220-33-2
- SCHEMBL129605
- SB10211
- FT-0605240
- FT-0630175
- UNII-CGW2AL7PQ7
- BDBM50561631
- CS-M2838
- PB32059
- M2115
- AKOS009157110
- FT-0605035
- AC-6615
- MFCD00003176
- AM20080233
- HY-I0708
- Q-201484
- MFCD03788748
- Q27275454
- NS00051700
- SY031540
- PB17320
- EN300-204124
- SY005849
- 3-Hydroxy-1-methylpyrrolidine;N-Methyl-3-pyrrolidinol
- DB-361411
- DB-014286
- 3Hydroxy1methylpyrrolidine
- DTXCID40812902
- 1Methylpyrrolidin3ol
-
- MDL： MFCD00003176
- Inchi： 1S/C5H11NO/c1-6-3-2-5(7)4-6/h5,7H,2-4H2,1H3
- InChI Key： FLVFPAIGVBQGET-UHFFFAOYSA-N
- SMILES： OC1CN(C)CC1
Computed Properties
- Exact Mass: 101.08400
- Monoisotopic Mass: 101.084
- Isotope Atom Count: 0
- Hydrogen Bond Donor Count: 1
- Hydrogen Bond Acceptor Count: 2
- Heavy Atom Count: 7
- Rotatable Bond Count: 0
- Complexity: 65.099
- Covalently-Bonded Unit Count: 1
- Defined Atom Stereocenter Count: 0
- Undefined Atom Stereocenter Count : 1
- Defined Bond Stereocenter Count: 0
- Undefined Bond Stereocenter Count: 0
- Surface Charge: 0
- Tautomer Count: nothing
- XLogP3: -0.2
- Topological Polar Surface Area: 23.5
Experimental Properties
- Color/Form: Liquid
- Density: 0.921?g/mL?at 25?°C(lit.)
- Melting Point: No data available
- Boiling Point: 75°C/12mmHg(lit.)
- Flash Point: Fahrenheit: 159.8 ° f < br / > Celsius: 71 ° C < br / >
- Refractive Index: n20/D 1.464(lit.)
- PSA: 23.47000
- LogP: -0.37930
- Solubility: Soluble in water, alcohol, ether and benzene.
1-Methyl-3-pyrrolidinol Security Information
- Prompt：warning
- Signal Word：Warning
- Hazard Statement： H227
- Warning Statement： P210-P280-P370+P378-P403+P235-P501
- Hazardous Material transportation number：NONH for all modes of transport
- WGK Germany：3
- Hazard Category Code： 36/37/38
- Safety Instruction： S26-S36/37/39
-
Hazardous Material Identification：
- Risk Phrases：R36/37/38
- Storage Condition：Store at room temperature
1-Methyl-3-pyrrolidinol Customs Data
- HS CODE：2933990090
- Customs Data：
China Customs Code:
2933990090Overview:
2933990090. Other heterocyclic compounds containing only nitrogen heteroatoms. VAT:17.0%. Tax refund rate:13.0%. Regulatory conditions:nothing. MFN tariff:6.5%. general tariff:20.0%
Declaration elements:
Product Name, component content, use to, Please indicate the appearance of Urotropine, 6- caprolactam please indicate the appearance, Signing date
Summary:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%
1-Methyl-3-pyrrolidinol Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| SHANG HAI XIAN DING Biotechnology Co., Ltd. | M070R-1g |
1-Methyl-3-pyrrolidinol |
13220-33-2 | 80% | 1g |
￥78.0 | 2022-05-30 | |
| SHANG HAI XIAN DING Biotechnology Co., Ltd. | M070R-5g |
1-Methyl-3-pyrrolidinol |
13220-33-2 | 97% | 5g |
￥257.0 | 2022-05-30 | |
| SHANG HAI XIAN DING Biotechnology Co., Ltd. | M2115-5G |
1-Methyl-3-pyrrolidinol |
13220-33-2 | 97.0%(T) | 5G |
￥290.0 | 2022-05-30 | |
| SHANG HAI XIAN DING Biotechnology Co., Ltd. | M2115-25G |
1-Methyl-3-pyrrolidinol |
13220-33-2 | 97.0%(T) | 25G |
￥990.0 | 2022-05-30 | |
| Alichem | A109006226-100g |
N-Methyl-3-pyrrolidinol |
13220-33-2 | 97% | 100g |
$345.42 | 2022-04-03 | |
| YAN FENG KE JI （ BEI JING ） Co., Ltd. | H85544-1g |
1-Methyl-3-pyrrolidinol |
13220-33-2 | 97% | 1g |
￥80 | 2023-09-19 | |
| YAN FENG KE JI （ BEI JING ） Co., Ltd. | H85544-5g |
1-Methyl-3-pyrrolidinol |
13220-33-2 | 97% | 5g |
￥220 | 2023-09-19 | |
| YAN FENG KE JI （ BEI JING ） Co., Ltd. | H85544-25g |
1-Methyl-3-pyrrolidinol |
13220-33-2 | 97% | 25g |
￥760 | 2023-09-19 | |
| Fluorochem | 040009-25g |
3-Hydroxy-1-methylpyrrolidine |
13220-33-2 | 97% | 25g |
￡148.00 | 2022-03-01 | |
| Fluorochem | 040009-100g |
3-Hydroxy-1-methylpyrrolidine |
13220-33-2 | 97% | 100g |
￡451.00 | 2022-03-01 |
1-Methyl-3-pyrrolidinol Production Method
Production Method 1
Reaction Conditions
1.1 Solvents: Water ; 4 - 5 min, cooled; 16 h, 100 °C
Reference
1-Methyl-3-pyrrolidinol Raw materials
1-Methyl-3-pyrrolidinol Preparation Products
1-Methyl-3-pyrrolidinol Suppliers
Suzhou Senfeida Chemical Co., Ltd
Gold Member
Audited Supplier
(CAS:13220-33-2)1-Methyl-3-pyrrolidinol
Order Number:1659423
Stock Status:in Stock
Quantity:Company Customization
Purity:98%
Pricing Information Last Updated:Monday, 14 April 2025 21:49
Price ($):discuss personally
Email:[email protected]
Tiancheng Chemical (Jiangsu) Co., Ltd
Gold Member
Audited Supplier
(CAS:13220-33-2)1-甲基-3-吡咯烷醇
Order Number:LE1659423
Stock Status:in Stock
Quantity:25KG,200KG,1000KG
Purity:99%
Pricing Information Last Updated:Friday, 20 June 2025 12:31
Price ($):discuss personally
Email:[email protected]
1-Methyl-3-pyrrolidinol Related Literature
-
Thanphat Thaima,Arife Yazici,Chiramet Auranwiwat,Anthony C. Willis,Uta Wille,Thunwadee Limtharakul,Stephen. G. Pyne Org. Biomol. Chem. 2021 19 259
13220-33-2 (1-Methyl-3-pyrrolidinol) Related Products
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