Cas no 106876-54-4 (2,2-difluoro-2H-1,3-benzodioxol-4-amine)
2,2-Difluoro-2H-1,3-benzodioxol-4-amine is a fluorinated benzodioxole derivative characterized by its unique structural features, including a difluoromethylene bridge and an amine functional group. This compound is of interest in pharmaceutical and agrochemical research due to its potential as a versatile intermediate. The presence of fluorine atoms enhances its metabolic stability and lipophilicity, making it valuable for the development of bioactive molecules. Its benzodioxole core contributes to electron-rich properties, facilitating further functionalization. The amine group allows for selective derivatization, enabling the synthesis of targeted compounds. This product is suitable for applications requiring precise molecular modifications in drug discovery and material science.
106876-54-4 structure
Product Name:2,2-difluoro-2H-1,3-benzodioxol-4-amine
CAS No:106876-54-4
MF:C7H5F2NO2
MW:173.116908788681
MDL:MFCD00792416
CID:62647
PubChem ID:2736891
Update Time:2025-06-08
2,2-difluoro-2H-1,3-benzodioxol-4-amine Chemical and Physical Properties
Names and Identifiers
-
- 4-Amino-2,2-difluoro-1,3-benzodioxole
- 2,2-DIFLUORO-4-AMINO-1,3-BENZODIOXOLE
- 2,2-DIFLUORO-4-AMINOBENZODIOXOLE
- 4-AMINO-2,2-DIFLUOROBENZODIOXOLE
- 2,2-difluoro-1,3-benzodioxol-4-amine
- 1,3-Benzodioxol-4-aMine, 2,2-difluoro-
- 2,2-difluorobenzo[d][1,3]dioxol-4-amine
- 2,2-difluoro-2H-1,3-benzodioxol-4-aMine
- 4-Amino-2,2-difluoro-1,3-benzodioxole98%
- 4-Amino-2,2-difluoro-1,3-benzodioxole 98%
- 4-Amino-2,2-difluoro-1,3-benzodioxole, 97+%
- C71267
- AKOS006229603
- 2,2-DIFLUORO-BENZO[1,3]DIOXOL-4-YLAMINE
- DS-12045
- EN300-3044071
- 4-amino-2,2-difluorobenzo-1,3-dioxole
- 4-Amino-2,2-difluoro-benzo(1.3)dioxole
- 4-Amino-2,2-difluorobenzo[d][1,3]dioxole
- CS-W017560
- SCHEMBL334653
- SY283191
- 2,3-(Difluoromethylenedioxy)aniline
- MFCD00792416
- DTXSID60371682
- AMY37101
- 4-amino-2,2-diflouro-1,3-benzodioxole
- 106876-54-4
- 4-Amino-2,2-difluoro-1,3-benzodioxole, AldrichCPR
- 2,2-difluoro-1,3-dioxaindan-4-amine
- A2047
- FT-0609232
- J-514312
- 2,2-Difluoro-1,3-benzodioxol-4-amine, 2,3-(Difluoromethylenedioxy)aniline
- 2,2-difluoro-2H-1,3-benzodioxol-4-amine
-
- MDL： MFCD00792416
- Inchi： 1S/C7H5F2NO2/c8-7(9)11-5-3-1-2-4(10)6(5)12-7/h1-3H,10H2
- InChI Key： RXIKYXZKSIARLN-UHFFFAOYSA-N
- SMILES： FC1(OC2C=CC=C(C=2O1)N)F
Computed Properties
- Exact Mass: 173.02900
- Monoisotopic Mass: 173.029
- Isotope Atom Count: 0
- Hydrogen Bond Donor Count: 1
- Hydrogen Bond Acceptor Count: 3
- Heavy Atom Count: 12
- Rotatable Bond Count: 0
- Complexity: 188
- Covalently-Bonded Unit Count: 1
- Defined Atom Stereocenter Count: 0
- Undefined Atom Stereocenter Count : 0
- Defined Bond Stereocenter Count: 0
- Undefined Bond Stereocenter Count: 0
- Topological Polar Surface Area: 44.5A^2
- Surface Charge: 0
- Tautomer Count: nothing
- XLogP3: 1.8
Experimental Properties
- Density: 1.51
- Boiling Point: 201 °C at 760 mmHg
- Flash Point: 75.4 °C
- Refractive Index: 1.556
- Water Partition Coefficient: Not miscible or difficult to mix in water.
- PSA: 44.48000
- LogP: 2.17150
- Solubility: Insoluble in water
2,2-difluoro-2H-1,3-benzodioxol-4-amine Security Information
- Hazard Statement： Toxic
- Hazardous Material transportation number：2810
- Hazard Category Code： R20/21/22: harmful by inhalation, skin contact and accidental swallowing. R36/37/38: irritating to eyes, respiratory tract and skin.
- Safety Instruction： S26-S36/37/39
-
Hazardous Material Identification：
- HazardClass：6.1
- PackingGroup：III
- Risk Phrases：R20/21/22
- Packing Group：III
- Safety Term：6.1
2,2-difluoro-2H-1,3-benzodioxol-4-amine Customs Data
- HS CODE：2932999099
- Customs Data：
China Customs Code:
2932999099Overview:
2932999099. Other heterocyclic compounds containing only oxygen heteroatoms. VAT:17.0%. Tax refund rate:13.0%. Regulatory conditions:nothing. MFN tariff:6.5%. general tariff:20.0%
Declaration elements:
Product Name, component content, use to
Summary:
2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%
2,2-difluoro-2H-1,3-benzodioxol-4-amine Pricemore >>
| Related Categories | No. | Product Name | Cas No. | Purity | Specification | Price | update time | Inquiry |
|---|---|---|---|---|---|---|---|---|
| TRC | A597208-50mg |
4-Amino-2,2-difluoro-1,3-benzodioxole |
106876-54-4 | 50mg |
$ 50.00 | 2022-06-08 | ||
| TRC | A597208-100mg |
4-Amino-2,2-difluoro-1,3-benzodioxole |
106876-54-4 | 100mg |
$ 65.00 | 2022-06-08 | ||
| TRC | A597208-500mg |
4-Amino-2,2-difluoro-1,3-benzodioxole |
106876-54-4 | 500mg |
$ 135.00 | 2022-06-08 | ||
| SHANG HAI MAI KE LIN SHENG HUA Technology Co., Ltd. | A895826-250mg |
4-Amino-2,2-difluoro-1,3-benzodioxole |
106876-54-4 | 96% | 250mg |
￥423.00 | 2022-09-02 | |
| SHANG HAI MAI KE LIN SHENG HUA Technology Co., Ltd. | A895826-1g |
4-Amino-2,2-difluoro-1,3-benzodioxole |
106876-54-4 | 96% | 1g |
￥1,066.50 | 2022-09-02 | |
| Apollo Scientific | PC3768-1g |
4-Amino-2,2-difluoro-1,3-benzodioxole |
106876-54-4 | 0.98 | 1g |
￡67.00 | 2025-02-21 | |
| Apollo Scientific | PC3768-5g |
4-Amino-2,2-difluoro-1,3-benzodioxole |
106876-54-4 | 0.98 | 5g |
￡280.00 | 2025-02-21 | |
| abcr | AB129167-250 mg |
2,2-Difluoro-4-amino-1,3-benzodioxole, 98%; . |
106876-54-4 | 98% | 250MG |
€113.50 | 2022-09-01 | |
| abcr | AB129167-1 g |
2,2-Difluoro-4-amino-1,3-benzodioxole, 98%; . |
106876-54-4 | 98% | 1g |
€153.30 | 2022-09-01 | |
| A FA AI SHA ， SAI MO FEI SHI ER KE JI QI XIA GONG SI | B22797-1g |
4-Amino-2,2-difluoro-1,3-benzodioxole, 97+% |
106876-54-4 | 97+% | 1g |
￥2528.00 | 2023-06-12 |
2,2-difluoro-2H-1,3-benzodioxol-4-amine Related Literature
-
Yang Chen,Di Zhou,Zheyi Meng,Jin Zhai Chem. Commun., 2016,52, 10020-10023
-
Yang Xu,Min Wang,Donghui Wei,Rongqiang Tian,Zheng Duan,Fran?ois Mathey Dalton Trans., 2019,48, 5523-5526
-
Alvin Tanudjaja,Shinsuke Inagi,Fusao Kitamura,Toshikazu Takata,Ikuyoshi Tomita Dalton Trans., 2021,50, 3037-3043
-
Luke L. Lairson,Warren W. Wakarchuk Chem. Commun., 2007, 365-367
-
Juan J. Sánchez,Miguel López-Haro,Juan C. Hernández-Garrido,Ginesa Blanco,Miguel A. Cauqui,José M. Rodríguez-Izquierdo,José A. Pérez-Omil,José J. Calvino,María P. Yeste J. Mater. Chem. A, 2019,7, 8993-9003
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