• 1. Fast-Track to Research Data Management in Experimental Material Science-Setting the Ground for Research Group Level Materials Digitalization.
  LarsBanko,AlfredLudwig
• 2. Establishment and implications of a characterization method for magnetic nanoparticle using cell tracking velocimetry and magnetic susceptibility modified solutions
  Huading Zhang,Lee R. Moore,Maciej Zborowski,P. Stephen Williams,Shlomo Margel,Jeffrey J. Chalmers Analyst, 2005,130, 514-527
• 3. Essential effect of the electrolyte on the mechanical and chemical degradation of LiNi0.8Co0.15Al0.05O2 cathodes upon long-term cycling??
  Xiaoming Liu,Zachary D. Hood,Wangda Li,Donovan N. Leonard,Arumugam Manthiram,Miaofang Chi J. Mater. Chem. A, 2021,9, 2111-2119
• 4. Esterase-responsive polymeric prodrug-based tumor targeting nanoparticles for improved anti-tumor performance against colon cancer?
  Gang Pan,Yi-jie Bao,Jie Xu,Tao Liu,Cheng Liu,Yan-yan Qiu,Xiao-jing Shi,Hui Yu,Ting-ting Jia,Xia Yuan,Ze-ting Yuan,Yi-jun Cao RSC Adv., 2016,6, 42109-42119
• 5. Fe3O4 nanoclusters highly dispersed on a porous graphene support as an additive for improving the hydrogen storage properties of LiBH4?
  Guang Xu,Wei Zhang,Ying Zhang,Xiaoxia Zhao,Ping Wen,Di Ma RSC Adv., 2018,8, 19353-19361

• Solvents and Organic Chemicals Organic Compounds Benzenoids Phenol ethers Aminophenyl ethers

Comprehensive Overview of 2-(Difluoromethoxy)-3-methoxyaniline hydrochloride (CAS No. 1431969-97-9)

2-(Difluoromethoxy)-3-methoxyaniline hydrochloride (CAS No. 1431969-97-9) is a specialized organic compound widely utilized in pharmaceutical and agrochemical research. This compound, characterized by its unique difluoromethoxy and methoxy functional groups, has garnered significant attention due to its potential applications in drug discovery and material science. Researchers are increasingly exploring its role as a key intermediate in synthesizing bioactive molecules, particularly those targeting central nervous system (CNS) disorders and inflammatory pathways.

The structural features of 2-(Difluoromethoxy)-3-methoxyaniline hydrochloride make it a valuable building block in medicinal chemistry. The presence of the difluoromethoxy group enhances metabolic stability and bioavailability, addressing a critical challenge in modern drug development. Recent studies highlight its utility in designing selective kinase inhibitors and GPCR modulators, aligning with the growing demand for precision therapeutics. As the pharmaceutical industry shifts toward personalized medicine, compounds like this are pivotal for creating targeted therapies with minimized side effects.

From a synthetic perspective, CAS No. 1431969-97-9 exemplifies the importance of halogenated aniline derivatives in organic synthesis. Its hydrochloride salt form improves solubility, facilitating reactions in aqueous environments—a trend driven by the push for green chemistry and sustainable practices. Laboratories worldwide are adopting this compound for high-throughput screening (HTS) due to its compatibility with automated synthesis platforms, reflecting the industry’s focus on AI-driven drug discovery and computational modeling.

Beyond pharmaceuticals, 2-(Difluoromethoxy)-3-methoxyaniline hydrochloride finds niche applications in advanced material science. Its fluorine-rich structure contributes to the development of liquid crystal displays (LCDs) and organic semiconductors, areas experiencing rapid growth due to the demand for flexible electronics. This dual applicability in life sciences and electronics positions the compound as a versatile tool for interdisciplinary research.

Quality control and analytical characterization of CAS No. 1431969-97-9 are critical for ensuring reproducibility in research. Techniques such as HPLC-MS and NMR spectroscopy are routinely employed to verify purity, a topic frequently searched by analytical chemists. The compound’s stability under various storage conditions (2-8°C, desiccated) is another common query, underscoring the need for detailed technical documentation.

In summary, 2-(Difluoromethoxy)-3-methoxyaniline hydrochloride represents a convergence of cutting-edge chemical innovation and practical utility. Its relevance to drug discovery, sustainable synthesis, and emerging technologies ensures its continued prominence in scientific literature and industrial applications. As research progresses, this compound is poised to play a pivotal role in addressing global health and technological challenges.

• 2098070-20-1(2-(3-(Pyridin-3-yl)-1H-pyrazol-1-yl)acetimidamide)
• 2680771-01-9(4-cyclopentyl-3-{(prop-2-en-1-yloxy)carbonylamino}butanoic acid)
• 1444113-98-7(N-(3-cyanothiolan-3-yl)-2-[(2,2,2-trifluoroethyl)sulfanyl]pyridine-4-carboxamide)
• 332062-08-5(Fmoc-S-3-amino-4,4-diphenyl-butyric acid)
• 1270529-38-8(1,2,3,4,5,6-Hexahydro-[2,3]bipyridinyl-6-ol)
• 941977-17-9(N'-(3-chloro-2-methylphenyl)-N-2-(dimethylamino)-2-(naphthalen-1-yl)ethylethanediamide)
• 2138166-62-6(2,2-Difluoro-3-[methyl(2-methylbutyl)amino]propanoic acid)
• 89640-58-4(2-Iodo-4-nitrophenylhydrazine)
• 1449132-38-0(3-Fluoro-5-(2-fluoro-5-methylbenzylcarbamoyl)benzeneboronic acid)
• 2034271-14-0(2-(1H-indol-3-yl)-N-{[6-(thiophen-2-yl)-[1,2,4]triazolo[4,3-b]pyridazin-3-yl]methyl}acetamide)