Cas no 10287-53-3 (Ethyl 4-dimethylaminobenzoate)

Ethyl 4-dimethylaminobenzoate, a derivative of benzoic acid, offers unique chemical properties. Its amine group enhances solubility in organic solvents, making it suitable for various applications. Its aromatic structure contributes to its stability and resistance to degradation, making it a valuable compound in pharmaceuticals and fragrances.

Ethyl 4-dimethylaminobenzoate structure

Product Name:Ethyl 4-dimethylaminobenzoate

CAS No:10287-53-3

MF:C₁₁H₁₅NO₂

MW:193.242303133011

MDL:MFCD00009115

CID:48494

Update Time:2026-05-14

Ethyl 4-dimethylaminobenzoate Chemical and Physical Properties

Names and Identifiers

- Ethyl 4-dimethylaminobenzoate
- 4-Dimethylaminobenzoic acid ethyl ester
- EDB
- Ethyl-4-(dimethylamino)benzoate
- Ethyl-4-dimethylamino benzoate
- Photoinitiator-EPD
- Ethyl 4-(Dimethylamino)benzoate
- Ethyl p-Dimethylaminobenzoate
- Ethyl-P-Dimethylaminobenzoate
- 4-(Dimethylamino)benzoic Acid Ethyl Ester
- Parbenate
- Ethyl p-N,N-dimethylaminobenzoate
- YF-PI EDB
- IHT-PI EDB
- HRcure-EDB
- SYNCURE EPD
- Darocur EDB
- OMNIRAD EDB
- Darocure EDB
- SPEEDCURE EDB
- 4-dimethylamino-benzoic acid ethyl ester
- Benzoic acid, 4-(dimethylamino)-, ethyl ester
- Kayacure EPA
- Ethyl-4-dimethylaminobenzoate
- N,N-Dimethylbenzocaine
- 829S8D3Y0X
- Genocure EPD
- Darocur EBD
- Quantacure epd
- PubChem20906
- Maybridge3_003189
- Benzoic
- MDL： MFCD00009115
- Inchi： 1S/C11H15NO2/c1-4-14-11(13)9-5-7-10(8-6-9)12(2)3/h5-8H,4H2,1-3H3
- InChI Key： FZUGPQWGEGAKET-UHFFFAOYSA-N
- SMILES： O(C([H])([H])C([H])([H])[H])C(C1C([H])=C([H])C(=C([H])C=1[H])N(C([H])([H])[H])C([H])([H])[H])=O
- BRN： 2210233

Computed Properties

Exact Mass: 193.11000
Monoisotopic Mass: 193.11
Isotope Atom Count: 0
Hydrogen Bond Donor Count: 0
Hydrogen Bond Acceptor Count: 3
Heavy Atom Count: 14
Rotatable Bond Count: 4
Complexity: 184
Covalently-Bonded Unit Count: 1
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count : 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Surface Charge: 0
Tautomer Count: nothing
XLogP3: 2.9
Topological Polar Surface Area: 29.5

Experimental Properties

Color/Form: White crystalline powder
Density: 1.061
Melting Point: 63-66?°C (lit.)
Boiling Point: 190-191°C 14mm
Flash Point: 190-191°C/14mm
Refractive Index: 1.5080 (estimate)
Water Partition Coefficient: Insoluble
Stability/Shelf Life: Stable. Incompatible with reducing agents, oxidizing agents, bases, acids.
PSA: 29.54000
LogP: 1.92930
Solubility: Insoluble in water.

Ethyl 4-dimethylaminobenzoate Security Information

Signal Word：Warning
Hazard Statement： H303,H313
Warning Statement： P312
Hazardous Material transportation number：NONH for all modes of transport
WGK Germany：3
Hazard Category Code： R36/37/38
Safety Instruction： S37/39-S26
Hazardous Material Identification：
TSCA：Yes
Storage Condition：Store at room temperature
Risk Phrases：R36/37/38
Safety Term：S26;S37/39

Ethyl 4-dimethylaminobenzoate Customs Data

HS CODE：29224995
Customs Data：

China Customs Code:
2922499990

Overview:

2922499990 Other amino acids and their esters and their salts(Except those containing more than one oxygen-containing group). VAT:17.0% Tax refund rate:9.0% Regulatory conditions:AB(Customs clearance form for Inbound Goods,Customs clearance form for outbound goods) MFN tariff:6.5% general tariff:30.0%

Declaration elements:

Product Name, component content, use to, The color of ethanolamine and its salt should be reported, The package of ethanolamine and its salt shall be declared

Regulatory conditions:

A.Customs clearance form for Inbound Goods
B.Customs clearance form for outbound goods

Inspection and quarantine category:

P.Imported animals and plants\Quarantine of animal and plant products
Q.Outbound animals and plants\Quarantine of animal and plant products
R.Sanitary supervision and inspection of imported food
S.Sanitary supervision and inspection of exported food
M.Import commodity inspection
N.Export commodity inspection

Summary:

HS:2922499990 other amino-acids, other than those containing more than one kind of oxygen function, and their esters; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:6.5% General tariff:30.0%

Ethyl 4-dimethylaminobenzoate Pricemore >>

Related Categories	No.	Product Name	Cas No.	Purity	Specification	Price	update time
SHANG HAI XIAN DING Biotechnology Co., Ltd.	D1744-25g	Ethyl 4-dimethylaminobenzoate	10287-53-3	98.0%(GC)	25g	￥130.0	2022-05-30
SHANG HAI XIAN DING Biotechnology Co., Ltd.	D1744-100g	Ethyl 4-dimethylaminobenzoate	10287-53-3	98.0%(GC)	100g	￥370.0	2022-05-30
SHANG HAI XIAN DING Biotechnology Co., Ltd.	D1744-500g	Ethyl 4-dimethylaminobenzoate	10287-53-3	98.0%(GC)	500g	￥965.0	2022-05-30
SHANG HAI XIAN DING Biotechnology Co., Ltd.	E184A-100g	Ethyl 4-dimethylaminobenzoate	10287-53-3	99%	100g	￥112.0	2022-05-30
SHANG HAI XIAN DING Biotechnology Co., Ltd.	E184A-25g	Ethyl 4-dimethylaminobenzoate	10287-53-3	99%	25g	￥51.0	2022-05-30
SHANG HAI XIAN DING Biotechnology Co., Ltd.	E184A-500g	Ethyl 4-dimethylaminobenzoate	10287-53-3	99%	500g	￥288.0	2022-05-30
XI GE MA AO DE LI QI （ SHANG HAI ） MAO YI Co., Ltd.	E24905-5G	Ethyl 4-dimethylaminobenzoate	10287-53-3		5g	￥522.23	2023-11-09
XI GE MA AO DE LI QI （ SHANG HAI ） MAO YI Co., Ltd.	E24905-100G	Ethyl 4-dimethylaminobenzoate	10287-53-3		100g	￥694.72	2023-11-09
XI GE MA AO DE LI QI （ SHANG HAI ） MAO YI Co., Ltd.	E24905-500G	Ethyl 4-dimethylaminobenzoate	10287-53-3		500g	￥2260.77	2023-11-09
Alichem	A019097515-100g	Ethyl 4-dimethylaminobenzoate	10287-53-3	97%	100g	$362.25	2023-09-04

Ethyl 4-dimethylaminobenzoate Production Method

Production Method 1

10287-53-3

Reaction Conditions

1.1R:NaBH3CN, S:AcOH, overnight, rt
1.2R:NaOH, S:H2O, 30 min, 0°C

Reference

: Synthesis of Phenols from Aryl Ammonium Salts under Mild Conditions

By Ni, Pufan et al, Journal of Organic Chemistry, 2022, 87(19), 12677-12687

Production Method 2

10541-82-9

10287-53-3

Reaction Conditions

1.1R:t-BuOK, C:RuCl3, S:MeOH, 36 h, 150°C

Reference

: Simple RuCl3-catalyzed N-Methylation of Amines and Transfer Hydrogenation of Nitroarenes using Methanol

By Sarki, Naina et al, ChemCatChem, 2021, 13(7), 1722-1729

Production Method 3

10287-53-3

Reaction Conditions

1.1R:HCO2Me, R:AcONa, S:MeOH, S:H2O, 24 h, 160°C

Reference

: Alkyl formates as reagents for reductive amination of carbonyl compounds

By Afanasyev, Oleg I. et al, Mendeleev Communications, 2020, 30(1), 112-113

Production Method 4

10287-53-3

Reaction Conditions

1.1R:Et3N, S:DMSO, 12-48 h, 150°C; 150°C → rt
1.2R:NaOH, S:H2O, rt, basify

Reference

: Highly Efficient Binuclear Copper-catalyzed Oxidation of N,N-Dimethylanilines with O2

By Liu, Yuxia et al, ChemCatChem, 2020, 12(8), 2221-2225

Production Method 5

1202-25-1

10287-53-3

Reaction Conditions

1.1R:H2, C:PtO2, rt → 60°C; 40 h, 60°C, 0.1-0.2 MPa

Reference

: Facile, highly efficient and environmentally friendly transesterification mediated by platinum dioxide and nickel oxide under essentially neutral conditions

By Teng, Binhao et al, Green Chemistry, 2018, 20(11), 2465-2471

Production Method 6

1942884-35-6

10287-53-3

Reaction Conditions

1.1R:Mn, C:CoBr2, C:Me3SiCl, C:2,2'-(C5H4N)2, S:DMF, S:C5H5N, 20 h, 60°C

Reference

: Cobalt-Catalyzed Esterification of Amides

By Bourne-Branchu, Yann et al, Chemistry - A European Journal, 2017, 23(42), 10043-10047

Production Method 7

586-77-6

10287-53-3

Reaction Conditions

1.1R:4-DMAP, C:PdCl2(PPh3)2, S:EtOH, 20 min, 140°C, 5-7 bar

Reference

: Diethyl oxalate as "CO" source for palladium-catalyzed ethoxycarbonylation of bromo- and chloroarene derivatives

By Monrose, Amandine et al, Advanced Synthesis & Catalysis, 2017, 359(15), 2699-2704

Production Method 8

84600-70-4

10287-53-3

Reaction Conditions

1.1R:(Me2N)3P=O, C:22784-59-4, S:PhMe, 100°C

Reference

: Ethyl chloroformate

By Payne, Andrew N. and Kobayashi, Yuichi, e-EROS Encyclopedia of Reagents for Organic Synthesis, 2005, From e-EROS Encyclopedia of Reagents for Organic Synthesis, 1-6

Production Method 9

10541-82-9

10287-53-3

Reaction Conditions

1.1R:Ph2SiH2, C:107-43-7, S:MeCN, rt; 12 h, 70°C, 1 bar

Reference

: Betaine Catalysis for Hierarchical Reduction of CO2 with Amines and Hydrosilane To Form Formamides, Aminals, and Methylamines

By Liu, Xiao-Fang et al, Angewandte Chemie, 2017, 56(26), 7425-7429

Production Method 10

10287-53-3

Reaction Conditions

1.1R:H2, C:Co(OAc)2, C:23582-02-7, C:Sn(O3SCF3)2, S:EtOH, 24 h, 125°C, 9 MPa

Reference

: Alcohol promoted N-methylation of anilines with CO2/H2 over a cobalt catalyst under mild conditions

By Ke, Zhengang et al, Green Chemistry, 2021, 23(22), 9147-9153

Production Method 11

619-84-1

10287-53-3

Reaction Conditions

1.1R:H2SO4, 2 h, 72°C

Reference

: Design, synthesis, in vitro and in vivo evaluation against MRSA and molecular docking studies of novel pleuromutilin derivatives bearing 1, 3, 4-oxadiazole linker

By Liu, Jie et al, Bioorganic Chemistry, 2021, 112, 104956

Production Method 12

133157-20-7

10287-53-3

Reaction Conditions

1.1R:PhSiH3, S:MeCN, 10 min, rt

Reference

: Metal-Free Deoxygenation of Amine N-Oxides: Synthetic and Mechanistic Studies

By Lecroq, William et al, ChemPhysChem, 2021, 22(12), 1237-1242

Production Method 13

619-84-1

72-40-2

10287-53-3

Reaction Conditions

1.1R:Et3N, S:MeCN, 5 min, rt
1.2rt; overnight, rt
2.1R:LiCl, S:H2O, rt
2.2R:AcOH, 30 min, rt
2.330 min, rt; rt → 0°C
2.4R:NaNO2, S:H2O, 0°C; 1 h, 0°C; 0°C → rt; 5 h, rt
3.1R:Disodium carbonate, S:H2O, S:Dioxane, 2 h, 60°C
3.24 h, 60°C

Reference

: Imidazotetrazines as Weighable Diazomethane Surrogates for Esterifications and Cyclopropanations

By Svec, Riley L. and Hergenrother, Paul J., Angewandte Chemie, 2020, 59(5), 1857-1862

Production Method 14

10287-53-3

Reaction Conditions

1.1R:H2SO4, R:NaBH4, S:H2O, S:THF, 0°C
1.2R:H2SO4, S:H2O, 0°C, acidify
1.3R:H2SO4, S:H2O, S:THF, 0°C
1.4S:H2O, 0°C
1.5R:KOH, 0°C, pH 10

Reference

: Reductive Coupling between C-N and C-O Electrophiles

By He, Rong-De et al, Journal of the American Chemical Society, 2019, 141(32), 12481-12486

Production Method 15

10541-82-9

10287-53-3

Reaction Conditions

1.1R:PhSiH3, S:DMF, 4 h, 80°C, 1 bar

Reference

: DMF-promoted reductive functionalization of CO2 with secondary amines and phenylsilane to methylamines

By Liu, Xiao-Fang et al, Pure and Applied Chemistry, 2018, 90(7), 1099-1107

Production Method 16

10287-53-3

Reaction Conditions

1.1R:Ph2SiH2, C:2254080-71-0, S:MeCN, 24 h, 120°C, 2.7 atm

Reference

: Diverse catalytic reactivity of a dearomatized PN3P*-nickel hydride pincer complex towards CO2 reduction

By Li, Huaifeng et al, Chemical Communications (Cambridge, 2018, 54(81), 11395-11398

Production Method 17

4755-50-4

497-25-6

10287-53-3

Reaction Conditions

1.1R:NaH, S:THF, 0°C; 10 min, 0°C; 45 min, rt
1.2overnight, rt
1.3R:H2O, 0°C
2.1C:54761-04-5, S:MeCN, 48 h, 90°C

Reference

: Broadly Applicable Ytterbium-Catalyzed Esterification, Hydrolysis, and Amidation of Imides

By Guissart, Celine et al, Organic Letters, 2018, 20(17), 5098-5102

Production Method 18

100-10-7

10287-53-3

Reaction Conditions

1.1R:O2, C:752-13-6, C:HCl, S:EtOH, S:MeCN, 12 h, cooled

Reference

: Visible-Light-Driven Aerobic Photooxidation of Aldehydes to Methyl Esters Catalyzed by Riboflavin Tetraacetate

By Muehldorf, Bernd and Wolf, Robert, ChemCatChem, 2017, 9(6), 920-923

Production Method 19

10541-82-9

10287-53-3

Reaction Conditions

1.1R:PhSiH3, S:DMF, 24 h, 90°C, 1 atm; 90°C → rt
1.2R:H2O, rt

Reference

: Catalyst-free N-methylation of amines using CO2

By Niu, Huiying et al, Chemical Communications (Cambridge, 2017, 53(6), 1148-1151

Production Method 20

10287-53-3

Reaction Conditions

1.1R:CaH2, C:Pd, S:5614-37-9, 16 h, 80°C

Reference

: Reductive N-methylation of amines with calcium hydride and Pd/C catalyst

By Guyon, Carole et al, Tetrahedron Letters, 2016, 57(27-28), 3002-3005

Ethyl 4-dimethylaminobenzoate Raw materials

Ethyl 4-dimethylaminobenzoate Preparation Products

Ethyl 4-dimethylaminobenzoate (10287-53-3)

Ethyl 4-dimethylaminobenzoate Suppliers

Tiancheng Chemical (Jiangsu) Co., Ltd

Gold Member

Audited Supplier

(CAS:10287-53-3)Ethyl 4-dimethylaminobenzoate

Order Number:LE7174;LE8665887;LE10616

Stock Status:in Stock

Quantity:25KG,200KG,1000KG

Purity:99%

Pricing Information Last Updated:Friday, 20 June 2025 11:50

Price ($):discuss personally

Email:[email protected]

Suzhou Senfeida Chemical Co., Ltd

Gold Member

Audited Supplier

(CAS:10287-53-3)Ethyl 4-dimethylaminobenzoate

Order Number:sfd16519

Stock Status:in Stock

Quantity:200kg

Purity:99.9%

Pricing Information Last Updated:Friday, 19 July 2024 14:37

Price ($):discuss personally

Email:[email protected]

Product Official Link

Jiangsu Xinsu New Materials Co., Ltd

Gold Member

Audited Supplier

(CAS:10287-53-3)

Order Number:SFD1128

Stock Status:in Stock

Quantity:25KG,200KG,1000KG

Purity:99%

Pricing Information Last Updated:Wednesday, 11 December 2024 17:02

Price ($):

Email:[email protected]

Ethyl 4-dimethylaminobenzoate Related Literature

1. Low volume shrinkage of polymers by photopolymerization of 1,1-bis(ethoxycarbonyl)-2-vinylcyclopropanes

Paul Pineda Contreras,Payal Tyagi,Seema Agarwal Polym. Chem. 2015 6 2297
2. Design of new phenothiazine derivatives as visible light photoinitiators

Mahmoud Rahal,Mira Abdallah,Thanh-Tuan Bui,Fabrice Goubard,Bernadette Graff,Frédéric Dumur,Joumana Toufaily,Tayssir Hamieh,Jacques Lalevée Polym. Chem. 2020 11 3349
3. Understanding the polarity of ionic liquids

M. A. Ab Rani,A. Brant,L. Crowhurst,A. Dolan,M. Lui,N. H. Hassan,J. P. Hallett,P. A. Hunt,H. Niedermeyer,J. M. Perez-Arlandis,M. Schrems,T. Welton,R. Wilding Phys. Chem. Chem. Phys. 2011 13 16831
4. Photoprotection or photodamage: a direct observation of nonradiative dynamics from 2-ethylhexyl 4-dimethylaminobenzoate sunscreen agent

Chensheng Ma,Chris Tsz-Leung Chan,Ruth Chau-Ting Chan,Allen Ka-Wa Wong,Bowie Po-Yee Chung,Wai-Ming Kwok Phys. Chem. Chem. Phys. 2018 20 24796
5. Probing stress relaxation behavior in glassy methacrylate networks containing thio-carbamate additives

A. P. P. Fugolin,A. R. Costa,S. H. Lewis,M. Goulart,M. C. Erhardt,C. S. Pfeifer J. Mater. Chem. B 2021 9 3015

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Recommended suppliers

Tiancheng Chemical (Jiangsu) Co., Ltd

(CAS:10287-53-3)Ethyl 4-dimethylaminobenzoate

Purity:99%/99%/99%

Quantity:25KG,200KG,1000KG/25KG,200KG,1000KG/25KG,200KG,1000KG

Price ($):Inquiry/Inquiry/Inquiry

Suzhou Senfeida Chemical Co., Ltd

(CAS:10287-53-3)Ethyl 4-dimethylaminobenzoate

Purity:99.9%

Quantity:200kg

Price ($):Inquiry

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Cas no 10287-53-3 (Ethyl 4-dimethylaminobenzoate)

Ethyl 4-dimethylaminobenzoate Chemical and Physical Properties

Names and Identifiers

Computed Properties

Experimental Properties

Ethyl 4-dimethylaminobenzoate Security Information

Ethyl 4-dimethylaminobenzoate Customs Data

China Customs Code:

Overview:

Declaration elements:

Regulatory conditions:

Inspection and quarantine category:

Summary:

Ethyl 4-dimethylaminobenzoate Pricemore >>

Ethyl 4-dimethylaminobenzoate Production Method

Production Method 1

Production Method 2

Production Method 3

Production Method 4

Production Method 5

Production Method 6

Production Method 7

Production Method 8

Production Method 9

Production Method 10

Production Method 11

Production Method 12

Production Method 13

Production Method 14

Production Method 15

Production Method 16

Production Method 17

Production Method 18

Production Method 19

Production Method 20

Ethyl 4-dimethylaminobenzoate Raw materials

Ethyl 4-dimethylaminobenzoate Preparation Products

Ethyl 4-dimethylaminobenzoate Suppliers

Ethyl 4-dimethylaminobenzoate Related Literature

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10287-53-3 (Ethyl 4-dimethylaminobenzoate) Related Products