Catalyst-free domino reaction in water/ethanol: an efficient, regio- and chemoselective one-pot multi-component synthesis of pyranopyrazole derivatives?
RSC Advances Pub Date: 2014-02-03 DOI: 10.1039/C3RA47639A
Abstract
The synthesis of pyrano[2,3-c]pyrazole derivatives has been described by regio- and chemoselective four-component reaction of a dialkyl 3-oxopentanedioate, an active carbonyl compound, hydrazine and malononitrile in water/ethanol as a green medium under catalyst-free condition.
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Journal Name：RSC Advances
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CAS no.: 89640-58-4
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