p-Toluenesulfonic acid-catalyzed regioselective C4–H iodination of isoquinolin-1(2H)-ones?
New Journal of Chemistry Pub Date: 2022-05-23 DOI: 10.1039/D2NJ00159D
Abstract
A general and efficient procedure for p-toluenesulfonic acid-catalyzed iodination of isoquinolin-1(2H)-ones with N-iodosuccinimide at room temperature is described. This method provides an alternative way of constructing C–I bonds, affords various 4-iodoisoquinolin-1(2H)-ones in moderate to good yields, and shows a broad substrate scope and good functional group tolerance.
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Journal Name：New Journal of Chemistry
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CAS no.: 89640-58-4
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