Tosyl/pyrrolyl-capped 1,3-enynes via t-BuOK-assisted reaction of TosMIC with acylethynylpyrroles: a new feature of this popular reagent?
New Journal of Chemistry Pub Date: 2022-08-10 DOI: 10.1039/D2NJ02827A
Abstract
1-Tosyl-4-pyrrolyl-1,3-enynes have been synthesized in 37–68% yields by t-BuOK-assisted chemo selective reaction (reflux in THF, 1 h) of 2-(acylethynyl)pyrroles with tosylmethylisocyanide (TosMIC), a widespread reagent, which here manifests a new functionality.
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Journal Name：New Journal of Chemistry
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CAS no.: 89640-58-4
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