The [4+1] cyclization reaction of 2-hydroxylimides and trimethylsulfoxonium iodide for the synthesis of 3-amino-2,3-dihydrobenzofurans?
New Journal of Chemistry Pub Date: 2022-09-13 DOI: 10.1039/D2NJ03131K
Abstract
The [4+1] cyclization reaction of 2-hydroxylimides and trimethylsulfoxonium iodide was investigated. This cyclization reaction exhibits wide scope and compatibility with functional groups. The 3-amino-2,3-dihydrobenzofurans were obtained in reasonable to high yields under mild conditions. This methodology was utilized to synthesize highly substituted 3-amino-2,3-dihydrobenzofuran derivatives.
![Graphical abstract: The [4+1] cyclization reaction of 2-hydroxylimides and trimethylsulfoxonium iodide for the synthesis of 3-amino-2,3-dihydrobenzofurans](http://scimg.chem960.com/usr/1/D2NJ03131K.jpg)
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Journal Name：New Journal of Chemistry
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CAS no.: 89640-58-4
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