Conversion of carbonyl compounds to alkynes: general overview and recent developments

Chemical Society Reviews Pub Date: 2010-03-24 DOI: 10.1039/B915418C

Abstract

The preparation of alkynes from carbonyl compounds via a one-carbon homologation has become a very useful pathway for the synthesis of acetylenic compounds, both internal and terminal. This tutorial review provides an overview of the different methods available for this transformation, including their scope and limitations, recent developments and applications in total syntheses.

Graphical abstract: Conversion of carbonyl compounds to alkynes: general overview and recent developments
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