The ligation of aspirin to cisplatin demonstrates significant synergistic effects on tumor cells?
Chemical Communications Pub Date: 2014-02-28 DOI: 10.1039/C4CC00419A
Abstract
Asplatin, a fusion of aspirin and cisplatin, exhibits significant cytotoxicity in tumor cells and almost fully overcomes the drug resistance of cisplatin resistant cells. Asplatin is highly accumulated in cancer cells and is activated upon the reduction by ascorbic acid.
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Journal Name：Chemical Communications
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CAS no.: 89640-58-4
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