Synthesis of rutaecarpine alkaloids via an electrochemical cross dehydrogenation coupling reaction?

Green Chemistry Pub Date: 2019-09-17 DOI: 10.1039/C9GC03028J

Abstract

Substrates are directly oxidized at the anode without using any metal catalyst and oxidant to obtain a series of nitrogen heterocyclic compounds, including benzimidazoles and quinolinones. These compounds are highly tolerant to various functional groups and heterocycle-containing substrates. In addition, natural alkaloids, such as rutaecarpine and deoxyvasicinone, can be synthesized by this method.

Graphical abstract: Synthesis of rutaecarpine alkaloids via an electrochemical cross dehydrogenation coupling reaction
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